Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220869834> ?p ?o ?g. }
- W4220869834 abstract "Head and neck squamous cell carcinoma (HNSCC) is the most common cancer involving the mucosal surfaces of the head and neck and is associated with a number of etiological factors, including cigarette smoking, alcohol and betel nut consumption and exposure to high-risk human papillomavirus. The risk of HNSCC increases with age, peaking in the seventh and eighth decade, but this varies by anatomical and histological subtype. While several advancements have been made in the treatment of head and neck cancer (HNC) in recent decades, undertaking curative treatment still subjects the majority of HNSCC patients to substantial treatment-related toxicity requiring patients to tolerate a gamut of physical, psychological, and emotional demands on their reserves. In conjunction with other patient-related factors, clinicians involved in treating patients with HNSCC may incorporate advancing chronological age into their decision-making process when determining treatment recommendations. While advancing chronological age may be associated with increased concerns regarding physical treatment tolerability, clinicians may also be concerned about heightened vulnerability in various health and wellbeing outcomes. The available literature, however, does not provide evidence of this vulnerability in patients with advancing age, and, in many instances, older patients self-report greater resilience compared to their younger counterparts. While this data is reassuring it is limited by selection bias and heterogeneity in trial and study design and the absence of a consistent definition of the elderly patient with HNSCC. This narrative review article also includes a review of the measures used to assess HRQL, psychosocial outcomes and unmet needs in elderly or older patients with HNSCC." @default.
- W4220869834 created "2022-04-03" @default.
- W4220869834 creator A5002541701 @default.
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- W4220869834 date "2022-02-15" @default.
- W4220869834 modified "2023-09-30" @default.
- W4220869834 title "Health-Related Quality of Life, Psychosocial Distress and Unmet Needs in Older Patients With Head and Neck Cancer" @default.
- W4220869834 cites W1487151488 @default.
- W4220869834 cites W1488865780 @default.
- W4220869834 cites W1518892660 @default.
- W4220869834 cites W1577268719 @default.
- W4220869834 cites W1606077938 @default.
- W4220869834 cites W1622845597 @default.
- W4220869834 cites W1722782033 @default.
- W4220869834 cites W1794310828 @default.
- W4220869834 cites W1819487784 @default.
- W4220869834 cites W1845447069 @default.
- W4220869834 cites W1854220427 @default.
- W4220869834 cites W1884363989 @default.
- W4220869834 cites W1918688730 @default.
- W4220869834 cites W1946263009 @default.
- W4220869834 cites W1947168884 @default.
- W4220869834 cites W1954726586 @default.
- W4220869834 cites W1968165262 @default.
- W4220869834 cites W1971194649 @default.
- W4220869834 cites W1971351343 @default.
- W4220869834 cites W1973812902 @default.
- W4220869834 cites W1974833358 @default.
- W4220869834 cites W1974839912 @default.
- W4220869834 cites W1975527653 @default.
- W4220869834 cites W1979603340 @default.
- W4220869834 cites W1981039202 @default.
- W4220869834 cites W1981488326 @default.
- W4220869834 cites W1982279098 @default.
- W4220869834 cites W1989429935 @default.
- W4220869834 cites W1991276220 @default.
- W4220869834 cites W1991276386 @default.
- W4220869834 cites W1996121545 @default.
- W4220869834 cites W1996704440 @default.
- W4220869834 cites W1997646508 @default.
- W4220869834 cites W1997927948 @default.
- W4220869834 cites W2001197156 @default.
- W4220869834 cites W2001287639 @default.
- W4220869834 cites W200201273 @default.
- W4220869834 cites W2005317392 @default.
- W4220869834 cites W2005636762 @default.
- W4220869834 cites W2006053083 @default.
- W4220869834 cites W2010479301 @default.
- W4220869834 cites W2012171271 @default.
- W4220869834 cites W2013886100 @default.
- W4220869834 cites W2015799750 @default.
- W4220869834 cites W2018782184 @default.
- W4220869834 cites W2019579922 @default.
- W4220869834 cites W2019713621 @default.
- W4220869834 cites W2021808126 @default.
- W4220869834 cites W2022634589 @default.
- W4220869834 cites W2022638253 @default.
- W4220869834 cites W2024958998 @default.
- W4220869834 cites W2025824972 @default.
- W4220869834 cites W2027488421 @default.
- W4220869834 cites W2030894553 @default.
- W4220869834 cites W2031515926 @default.
- W4220869834 cites W2032493463 @default.
- W4220869834 cites W2032529337 @default.
- W4220869834 cites W2034917949 @default.
- W4220869834 cites W2042554097 @default.
- W4220869834 cites W2044807433 @default.
- W4220869834 cites W2051922727 @default.
- W4220869834 cites W2054527785 @default.
- W4220869834 cites W2056520478 @default.
- W4220869834 cites W2057844740 @default.
- W4220869834 cites W2059715658 @default.
- W4220869834 cites W2059859004 @default.
- W4220869834 cites W2060906857 @default.
- W4220869834 cites W2061378977 @default.
- W4220869834 cites W2061992835 @default.
- W4220869834 cites W2063547370 @default.
- W4220869834 cites W2064480128 @default.
- W4220869834 cites W2066264200 @default.
- W4220869834 cites W2066310418 @default.
- W4220869834 cites W2067679202 @default.
- W4220869834 cites W2068511425 @default.
- W4220869834 cites W2071396284 @default.
- W4220869834 cites W2074704325 @default.
- W4220869834 cites W2074710703 @default.
- W4220869834 cites W2077257970 @default.
- W4220869834 cites W2086628683 @default.
- W4220869834 cites W2087057250 @default.
- W4220869834 cites W2089257078 @default.
- W4220869834 cites W2090645934 @default.
- W4220869834 cites W2091489114 @default.
- W4220869834 cites W2094815648 @default.
- W4220869834 cites W2096286179 @default.
- W4220869834 cites W2101591333 @default.
- W4220869834 cites W2103607521 @default.
- W4220869834 cites W2103995559 @default.
- W4220869834 cites W2105258029 @default.
- W4220869834 cites W2105931591 @default.