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- W4220883032 abstract "Abstract Purpose: Accumulating researches have observed the potential association between osteoporosis and hypertension, however, the evidence regarding gender-difference association between divergent proxies of blood pressure and osteoporosis was limited in rural areas. Methods: A total of 7689 participants enrolled from Henan Rural Cohort study were included in this research. Four proxies (systolic blood pressure (SBP); diastolic blood pressure (DBP); mean arterial pressure (MAP); pulse pressure (PP)) of blood pressure were measured. The association between blood pressure and osteoporosis was assessed by binary logistic regression with adjustment of potential influencing factors. All analyses were stratified by gender. To test the robust of results, similar analyses were also conducted in non-hypertension participants and postmenopausal women. Results: The significantly positive association between hypertension and osteoporosis was observed among women but not in men. Increasing blood pressure corresponded with prevalent osteoporosis among women, in which each 10 mmHg increase in SBP, MAP, and PP corresponded with 1.07-fold (1.03, 1.12), 1.14-fold (1.07, 1.21), and 1.08-fold (1.02, 1.15) prevalence of osteoporosis, respectively. This positive association was still significant among non-hypertension women and postmenopausal women, but not in pre-menopausal women. Conclusion: In rural areas, there was a positive association between blood pressure and prevalent osteoporosis in women, but not in men. Menopausal status may be responsible for this gender-difference." @default.
- W4220883032 created "2022-04-03" @default.
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- W4220883032 date "2022-03-08" @default.
- W4220883032 modified "2023-10-17" @default.
- W4220883032 title "Gender-Difference Association Between Blood Pressure And Osteoporosis: Results From Henan Rural Cohort Study" @default.
- W4220883032 doi "https://doi.org/10.21203/rs.3.rs-1398784/v1" @default.
- W4220883032 hasPublicationYear "2022" @default.
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