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• W4220888944 abstract "Both sensory and metabolic processes guide food intake. Olfactory inputs help coordinate food appreciation and selection, but their role in food consumption and post-feeding physiology remains poorly understood. In this study, using Drosophila melanogaster as a model system, we investigated the effects of olfactory sensory neurons (OSNs) on food consumption, metabolism, and stress responses. We found that dysfunction of OSNs affects diverse processes, including decreased food consumption, increased triacylglycerol level, enhanced stress resistance to starvation or desiccation, and decreased cold resistance. Decreased neuropeptide F receptor (NPFR) level or increased insulin activity in OSNs inhibited food consumption, while impaired NPF signaling or insulin signaling in OSNs increased resistance to starvation and desiccation. These studies provide insights into the function of the olfactory system in control of feeding behaviors and physiology." @default.
• W4220888944 created "2022-04-03" @default.
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• W4220888944 date "2022-04-01" @default.
• W4220888944 modified "2023-10-16" @default.
• W4220888944 title "Olfactory Senses Modulate Food Consumption and Physiology in Drosophila melanogaster" @default.
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• W4220888944 doi "https://doi.org/10.3389/fnbeh.2022.788633" @default.
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