FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220897798> ?p ?o ?g. }

• W4220897798 endingPage "132838" @default.
• W4220897798 startingPage "132838" @default.
• W4220897798 abstract "G-Quadruplexes exist in cells and are involved in several cancer-related processes. Thus, G-quadruplex binding is an effective way of aiming at cancer cells. In this paper, the binding of a new β-cyclodextrin conjugate, eosin yellow-CD, with quadruplex DNAs viz., kit22, myc22, telo24 and duplex calf-thymus DNA, is studied by UV–vis and fluorescence spectroscopic methods. Berberine, a known G-quadruplex binder, is loaded in the modified cyclodextrin. The binding constant of the host: guest complex is 1.9 × 106 mol−1 dm3. The proximity of the protons of the conjugate and Berberine with those of the internal cavity of β-cyclodextrin in the conjugate is confirmed by two-dimensional rotating-frame Overhauser effect spectroscopy. The conjugate displays a quenching of fluorescence selectively to the quadruplex kit22 and telo24 that contrasts the spectral characteristics of the ligand-bound complexes of myc22 and ctDNA. The Stern-Volmer quenching constants are 1.08 × 106 mol−1 dm3 and 1.6 × 106 mol−1 dm3, respectively for binding to kit22 and telo24. The duplex ctDNA exhibits an enhanced fluorescence in the absence and the presence of Berberine complex, whereas the quadrulex DNAs exhibit dissimilar emission profiles when the eosin yellow-CD encapsulates Berberine. We report the differences in the binding constants and the mode of binding of free- and Berberine-loaded eosin yellow-CD to the duplex and quadruplex DNAs." @default.
• W4220897798 created "2022-04-03" @default.
• W4220897798 creator A5003162293 @default.
• W4220897798 creator A5010515340 @default.
• W4220897798 creator A5024838157 @default.
• W4220897798 creator A5042489908 @default.
• W4220897798 creator A5049220314 @default.
• W4220897798 creator A5057596928 @default.
• W4220897798 date "2022-07-01" @default.
• W4220897798 modified "2023-10-16" @default.
• W4220897798 title "Molecular encapsulation by eosin yellow-β-cyclodextrin conjugate: Differential binding to quadruplex and duplex DNA" @default.
• W4220897798 cites W1936894426 @default.
• W4220897798 cites W1946594578 @default.
• W4220897798 cites W1970623750 @default.
• W4220897798 cites W2001855322 @default.
• W4220897798 cites W2010675785 @default.
• W4220897798 cites W2036754777 @default.
• W4220897798 cites W2038871984 @default.
• W4220897798 cites W2068122257 @default.
• W4220897798 cites W2083740742 @default.
• W4220897798 cites W2093248801 @default.
• W4220897798 cites W2101309212 @default.
• W4220897798 cites W2137500638 @default.
• W4220897798 cites W2171830519 @default.
• W4220897798 cites W2290989326 @default.
• W4220897798 cites W2555276918 @default.
• W4220897798 cites W2769520992 @default.
• W4220897798 cites W2769533173 @default.
• W4220897798 cites W2781995983 @default.
• W4220897798 cites W2885844771 @default.
• W4220897798 cites W2946935067 @default.
• W4220897798 cites W2992882537 @default.
• W4220897798 cites W3003540629 @default.
• W4220897798 cites W3020046462 @default.
• W4220897798 cites W3027168057 @default.
• W4220897798 cites W3045727469 @default.
• W4220897798 cites W3097469518 @default.
• W4220897798 doi "https://doi.org/10.1016/j.molstruc.2022.132838" @default.
• W4220897798 hasPublicationYear "2022" @default.
• W4220897798 type Work @default.
• W4220897798 citedByCount "4" @default.
• W4220897798 countsByYear W42208977982022 @default.
• W4220897798 countsByYear W42208977982023 @default.
• W4220897798 crossrefType "journal-article" @default.
• W4220897798 hasAuthorship W4220897798A5003162293 @default.
• W4220897798 hasAuthorship W4220897798A5010515340 @default.
• W4220897798 hasAuthorship W4220897798A5024838157 @default.
• W4220897798 hasAuthorship W4220897798A5042489908 @default.
• W4220897798 hasAuthorship W4220897798A5049220314 @default.
• W4220897798 hasAuthorship W4220897798A5057596928 @default.
• W4220897798 hasConcept C107824862 @default.
• W4220897798 hasConcept C121332964 @default.
• W4220897798 hasConcept C121745418 @default.
• W4220897798 hasConcept C134306372 @default.
• W4220897798 hasConcept C142724271 @default.
• W4220897798 hasConcept C185592680 @default.
• W4220897798 hasConcept C197336794 @default.
• W4220897798 hasConcept C2779433975 @default.
• W4220897798 hasConcept C2779751288 @default.
• W4220897798 hasConcept C2780116568 @default.
• W4220897798 hasConcept C32786932 @default.
• W4220897798 hasConcept C33923547 @default.
• W4220897798 hasConcept C43617362 @default.
• W4220897798 hasConcept C552990157 @default.
• W4220897798 hasConcept C55493867 @default.
• W4220897798 hasConcept C62520636 @default.
• W4220897798 hasConcept C71240020 @default.
• W4220897798 hasConcept C71924100 @default.
• W4220897798 hasConcept C74864618 @default.
• W4220897798 hasConcept C75473681 @default.
• W4220897798 hasConcept C83762044 @default.
• W4220897798 hasConcept C91881484 @default.
• W4220897798 hasConcept C99611785 @default.
• W4220897798 hasConceptScore W4220897798C107824862 @default.
• W4220897798 hasConceptScore W4220897798C121332964 @default.
• W4220897798 hasConceptScore W4220897798C121745418 @default.
• W4220897798 hasConceptScore W4220897798C134306372 @default.
• W4220897798 hasConceptScore W4220897798C142724271 @default.
• W4220897798 hasConceptScore W4220897798C185592680 @default.
• W4220897798 hasConceptScore W4220897798C197336794 @default.
• W4220897798 hasConceptScore W4220897798C2779433975 @default.
• W4220897798 hasConceptScore W4220897798C2779751288 @default.
• W4220897798 hasConceptScore W4220897798C2780116568 @default.
• W4220897798 hasConceptScore W4220897798C32786932 @default.
• W4220897798 hasConceptScore W4220897798C33923547 @default.
• W4220897798 hasConceptScore W4220897798C43617362 @default.
• W4220897798 hasConceptScore W4220897798C552990157 @default.
• W4220897798 hasConceptScore W4220897798C55493867 @default.
• W4220897798 hasConceptScore W4220897798C62520636 @default.
• W4220897798 hasConceptScore W4220897798C71240020 @default.
• W4220897798 hasConceptScore W4220897798C71924100 @default.
• W4220897798 hasConceptScore W4220897798C74864618 @default.
• W4220897798 hasConceptScore W4220897798C75473681 @default.
• W4220897798 hasConceptScore W4220897798C83762044 @default.
• W4220897798 hasConceptScore W4220897798C91881484 @default.
• W4220897798 hasConceptScore W4220897798C99611785 @default.
• W4220897798 hasFunder F4320335179 @default.
• W4220897798 hasLocation W42208977981 @default.

• next