Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220904265> ?p ?o ?g. }
- W4220904265 endingPage "100942" @default.
- W4220904265 startingPage "100942" @default.
- W4220904265 abstract "It is estimated that by 2050 one in every ten people will be suffering from disabling hearing loss. Perforated tympanic membranes (TMs) are the most common injury to the human ear, resulting in a partial or complete hearing loss due to inept sound conduction. Commonly known as the eardrum, the TM is a thin, concave tissue of the middle ear that captures sound pressure waves from the environment and transmits them as mechanical vibrations to the inner ear. Microsurgical placement of autologous tissue graft has been the “gold standard” for treating damaged TMs; however, the incongruent structural and mechanical properties of these autografts often impair an optimal hearing restoration following recovery. Moreover, given the lack of available tissues for transplantations, regenerative medicine has emerged as a promising alternative. Several tissue engineered approaches applying bio-instructive scaffolds and stimuli have been reported for the TM regeneration, which can be broadly classified into TM repair and TM reconstruction. This review evaluates the current advantages and challenges of both strategies with a special focus on the use of recent biofabrication technologies for advancing TM tissue engineering." @default.
- W4220904265 created "2022-04-03" @default.
- W4220904265 creator A5021518456 @default.
- W4220904265 creator A5048764855 @default.
- W4220904265 creator A5058423562 @default.
- W4220904265 creator A5058979303 @default.
- W4220904265 date "2022-06-01" @default.
- W4220904265 modified "2023-09-30" @default.
- W4220904265 title "Regenerative therapies for tympanic membrane" @default.
- W4220904265 cites W114129597 @default.
- W4220904265 cites W1502960530 @default.
- W4220904265 cites W1515355904 @default.
- W4220904265 cites W1586551928 @default.
- W4220904265 cites W1689662055 @default.
- W4220904265 cites W1691690006 @default.
- W4220904265 cites W1845847174 @default.
- W4220904265 cites W1905065343 @default.
- W4220904265 cites W1963717365 @default.
- W4220904265 cites W1964559470 @default.
- W4220904265 cites W1966195578 @default.
- W4220904265 cites W1966887569 @default.
- W4220904265 cites W1969539757 @default.
- W4220904265 cites W1971500643 @default.
- W4220904265 cites W1972804317 @default.
- W4220904265 cites W1973855859 @default.
- W4220904265 cites W1974942131 @default.
- W4220904265 cites W1975138674 @default.
- W4220904265 cites W1975237289 @default.
- W4220904265 cites W1977662606 @default.
- W4220904265 cites W1978158011 @default.
- W4220904265 cites W1978552078 @default.
- W4220904265 cites W1980239455 @default.
- W4220904265 cites W1982736932 @default.
- W4220904265 cites W1983461867 @default.
- W4220904265 cites W1989246215 @default.
- W4220904265 cites W1991672292 @default.
- W4220904265 cites W1993527894 @default.
- W4220904265 cites W1995230762 @default.
- W4220904265 cites W1995698092 @default.
- W4220904265 cites W1996218878 @default.
- W4220904265 cites W1996296734 @default.
- W4220904265 cites W1999278855 @default.
- W4220904265 cites W2000537455 @default.
- W4220904265 cites W2002695868 @default.
- W4220904265 cites W2007532288 @default.
- W4220904265 cites W2015342049 @default.
- W4220904265 cites W2015638950 @default.
- W4220904265 cites W2023166500 @default.
- W4220904265 cites W2024788464 @default.
- W4220904265 cites W2026465838 @default.
- W4220904265 cites W2026975571 @default.
- W4220904265 cites W2030562975 @default.
- W4220904265 cites W2032573939 @default.
- W4220904265 cites W2035361700 @default.
- W4220904265 cites W2035811626 @default.
- W4220904265 cites W2036122797 @default.
- W4220904265 cites W2036728366 @default.
- W4220904265 cites W2043229941 @default.
- W4220904265 cites W2043846971 @default.
- W4220904265 cites W2047043310 @default.
- W4220904265 cites W2047646146 @default.
- W4220904265 cites W2048311976 @default.
- W4220904265 cites W2048392852 @default.
- W4220904265 cites W2048644480 @default.
- W4220904265 cites W2050535601 @default.
- W4220904265 cites W2052318709 @default.
- W4220904265 cites W2055818169 @default.
- W4220904265 cites W2057428911 @default.
- W4220904265 cites W2059593645 @default.
- W4220904265 cites W2060336285 @default.
- W4220904265 cites W2061914961 @default.
- W4220904265 cites W2062501390 @default.
- W4220904265 cites W2068073099 @default.
- W4220904265 cites W2068497715 @default.
- W4220904265 cites W2075870527 @default.
- W4220904265 cites W2080418053 @default.
- W4220904265 cites W2081422049 @default.
- W4220904265 cites W2083901473 @default.
- W4220904265 cites W2084118140 @default.
- W4220904265 cites W2084247413 @default.
- W4220904265 cites W2084535470 @default.
- W4220904265 cites W2086172513 @default.
- W4220904265 cites W2086263913 @default.
- W4220904265 cites W2091596562 @default.
- W4220904265 cites W2094791419 @default.
- W4220904265 cites W2098901994 @default.
- W4220904265 cites W2101601223 @default.
- W4220904265 cites W2102336690 @default.
- W4220904265 cites W2103827209 @default.
- W4220904265 cites W2105271347 @default.
- W4220904265 cites W2106727463 @default.
- W4220904265 cites W2107731137 @default.
- W4220904265 cites W2108371710 @default.
- W4220904265 cites W2109972450 @default.
- W4220904265 cites W2110313479 @default.
- W4220904265 cites W2116489560 @default.
- W4220904265 cites W2119783711 @default.
- W4220904265 cites W2121275713 @default.