FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220923786> ?p ?o ?g. }

• W4220923786 abstract "Liver transplantation (LT) is frequently complicated by coagulopathy associated with end-stage liver disease (ESLD), that is, often multifactorial.The objective of this systematic review was to identify evidence based intraoperative transfusion and coagulation management strategies that improve immediate and short-term outcomes after LT.PRISMA-guidelines and GRADE-approach were followed. Three subquestions were formulated. (Q); Q1: transfusion management; Q2: antifibrinolytic therapy; and Q3: coagulation monitoring.Sixteen studies were included for Q1, six for Q2, and 10 for Q3. Q1: PRBC and platelet transfusions were associated with higher mortality. The use of prothrombin complex concentrate (PCC) and fibrinogen concentrate (FC) were not associated with reductions in intraoperative transfusion or increased thrombotic events. The use of cell salvage was not associated with hepatocellular carcinoma (HCC) recurrence or mortality. Cell salvage and transfusion education significantly decreased blood product transfusions. Q2: Epsilon-aminocaproic acid (EACA) and tranexamic acid (TXA) were not associated with decreased blood product transfusion, improvements in patient or graft survival, or increases in thrombotic events. Q3: Viscoelastic testing (VET) was associated with decreased allogeneic blood product transfusion compared to conventional coagulation tests (CCT) and is likely to be cost-effective. Coagulation management guided by VET may be associated with increases in FC and PCC use.Q1: A specific blood product transfusion practice is not recommended (QOE; low | Recommendation; weak). Cell salvage and educational interventions are recommended (QOE: low | Grade of Recommendation: moderate). Q2: The routine use of antifibrinolytics is not recommended (QOE; low | Recommendation; weak). Q3: The use of VET is recommended (QOE; low-moderate | Recommendation; strong)." @default.
• W4220923786 created "2022-04-03" @default.
• W4220923786 creator A5017717954 @default.
• W4220923786 creator A5021700280 @default.
• W4220923786 creator A5030321053 @default.
• W4220923786 creator A5038548099 @default.
• W4220923786 creator A5041092138 @default.
• W4220923786 creator A5043619975 @default.
• W4220923786 creator A5064512877 @default.
• W4220923786 creator A5077960444 @default.
• W4220923786 creator A5078254820 @default.
• W4220923786 creator A9999999999 @default.
• W4220923786 date "2022-10-01" @default.
• W4220923786 modified "2023-10-16" @default.
• W4220923786 title "Intraoperative transfusion management, antifibrinolytic therapy, coagulation monitoring and the impact on short‐term outcomes after liver transplantation—A systematic review of the literature and expert panel recommendations" @default.
• W4220923786 cites W1130343390 @default.
• W4220923786 cites W1562275781 @default.
• W4220923786 cites W1897201389 @default.
• W4220923786 cites W1964888177 @default.
• W4220923786 cites W1980228567 @default.
• W4220923786 cites W1986665218 @default.
• W4220923786 cites W2003549934 @default.
• W4220923786 cites W2022689571 @default.
• W4220923786 cites W2026648151 @default.
• W4220923786 cites W2031164481 @default.
• W4220923786 cites W2031620170 @default.
• W4220923786 cites W2067661817 @default.
• W4220923786 cites W2072279872 @default.
• W4220923786 cites W2074969169 @default.
• W4220923786 cites W2091664212 @default.
• W4220923786 cites W2095567130 @default.
• W4220923786 cites W2096074908 @default.
• W4220923786 cites W2104675861 @default.
• W4220923786 cites W2107522704 @default.
• W4220923786 cites W2112182430 @default.
• W4220923786 cites W2116098784 @default.
• W4220923786 cites W2160759876 @default.
• W4220923786 cites W2171993752 @default.
• W4220923786 cites W2185654166 @default.
• W4220923786 cites W2334764032 @default.
• W4220923786 cites W2363556660 @default.
• W4220923786 cites W2514036270 @default.
• W4220923786 cites W2560342826 @default.
• W4220923786 cites W2587560133 @default.
• W4220923786 cites W2603520596 @default.
• W4220923786 cites W2743774649 @default.
• W4220923786 cites W2756510800 @default.
• W4220923786 cites W2766675625 @default.
• W4220923786 cites W2781575872 @default.
• W4220923786 cites W2790132222 @default.
• W4220923786 cites W2791828149 @default.
• W4220923786 cites W2903782095 @default.
• W4220923786 cites W2904818141 @default.
• W4220923786 cites W2905925403 @default.
• W4220923786 cites W2925855415 @default.
• W4220923786 cites W2953860874 @default.
• W4220923786 cites W2978440414 @default.
• W4220923786 cites W2994970955 @default.
• W4220923786 cites W3005300671 @default.
• W4220923786 cites W3010359653 @default.
• W4220923786 cites W3025718048 @default.
• W4220923786 cites W3093691046 @default.
• W4220923786 cites W3107357219 @default.
• W4220923786 cites W3173312086 @default.
• W4220923786 cites W3196818682 @default.
• W4220923786 doi "https://doi.org/10.1111/ctr.14637" @default.
• W4220923786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35249250" @default.
• W4220923786 hasPublicationYear "2022" @default.
• W4220923786 type Work @default.
• W4220923786 citedByCount "15" @default.
• W4220923786 countsByYear W42209237862022 @default.
• W4220923786 countsByYear W42209237862023 @default.
• W4220923786 crossrefType "journal-article" @default.
• W4220923786 hasAuthorship W4220923786A5017717954 @default.
• W4220923786 hasAuthorship W4220923786A5021700280 @default.
• W4220923786 hasAuthorship W4220923786A5030321053 @default.
• W4220923786 hasAuthorship W4220923786A5038548099 @default.
• W4220923786 hasAuthorship W4220923786A5041092138 @default.
• W4220923786 hasAuthorship W4220923786A5043619975 @default.
• W4220923786 hasAuthorship W4220923786A5064512877 @default.
• W4220923786 hasAuthorship W4220923786A5077960444 @default.
• W4220923786 hasAuthorship W4220923786A5078254820 @default.
• W4220923786 hasAuthorship W4220923786A9999999999 @default.
• W4220923786 hasConcept C126322002 @default.
• W4220923786 hasConcept C141071460 @default.
• W4220923786 hasConcept C177713679 @default.
• W4220923786 hasConcept C2776301958 @default.
• W4220923786 hasConcept C2777075537 @default.
• W4220923786 hasConcept C2777091921 @default.
• W4220923786 hasConcept C2777396833 @default.
• W4220923786 hasConcept C2778382381 @default.
• W4220923786 hasConcept C2779161974 @default.
• W4220923786 hasConcept C2779250428 @default.
• W4220923786 hasConcept C2779609443 @default.
• W4220923786 hasConcept C2779637338 @default.
• W4220923786 hasConcept C2779936836 @default.
• W4220923786 hasConcept C2780434524 @default.
• W4220923786 hasConcept C2781436528 @default.
• W4220923786 hasConcept C2911091166 @default.
• W4220923786 hasConcept C2991743468 @default.

• next