Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220927418> ?p ?o ?g. }
- W4220927418 endingPage "100188" @default.
- W4220927418 startingPage "100188" @default.
- W4220927418 abstract "Master transcription factors (TFs) directly regulate present and future cell states by binding DNA regulatory elements and driving gene-expression programs. Their abundance influences epigenetic priming to different cell fates at the chromatin level, especially in the context of differentiation. In order to link TF protein abundance to changes in TF motif accessibility and open chromatin, we developed InTAC-seq, a method for simultaneous quantification of genome-wide chromatin accessibility and intracellular protein abundance in fixed cells. Our method produces high-quality data and is a cost-effective alternative to single-cell techniques. We showcase our method by purifying bone marrow (BM) progenitor cells based on GATA-1 protein levels and establish high GATA-1-expressing BM cells as both epigenetically and functionally similar to erythroid-committed progenitors." @default.
- W4220927418 created "2022-04-03" @default.
- W4220927418 creator A5014019530 @default.
- W4220927418 creator A5026021659 @default.
- W4220927418 creator A5044620954 @default.
- W4220927418 creator A5045383208 @default.
- W4220927418 creator A5046490978 @default.
- W4220927418 creator A5056566361 @default.
- W4220927418 creator A5059036898 @default.
- W4220927418 creator A5066136174 @default.
- W4220927418 creator A5069003224 @default.
- W4220927418 creator A5071618928 @default.
- W4220927418 creator A5078529502 @default.
- W4220927418 date "2022-03-01" @default.
- W4220927418 modified "2023-10-14" @default.
- W4220927418 title "Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment" @default.
- W4220927418 cites W1504158565 @default.
- W4220927418 cites W1508593718 @default.
- W4220927418 cites W1608560430 @default.
- W4220927418 cites W1751344558 @default.
- W4220927418 cites W1886102483 @default.
- W4220927418 cites W1973268693 @default.
- W4220927418 cites W1978683461 @default.
- W4220927418 cites W1984407446 @default.
- W4220927418 cites W1986712427 @default.
- W4220927418 cites W1999705778 @default.
- W4220927418 cites W2007625577 @default.
- W4220927418 cites W2028695285 @default.
- W4220927418 cites W2030628887 @default.
- W4220927418 cites W2031418587 @default.
- W4220927418 cites W2036897871 @default.
- W4220927418 cites W2045362835 @default.
- W4220927418 cites W2049117415 @default.
- W4220927418 cites W2050339753 @default.
- W4220927418 cites W2053577848 @default.
- W4220927418 cites W2064993419 @default.
- W4220927418 cites W2066721422 @default.
- W4220927418 cites W2071151794 @default.
- W4220927418 cites W2073256527 @default.
- W4220927418 cites W2080961105 @default.
- W4220927418 cites W2083682077 @default.
- W4220927418 cites W2084407030 @default.
- W4220927418 cites W2087731236 @default.
- W4220927418 cites W2090786449 @default.
- W4220927418 cites W2098528717 @default.
- W4220927418 cites W2106658907 @default.
- W4220927418 cites W2110981938 @default.
- W4220927418 cites W2113260405 @default.
- W4220927418 cites W2117757143 @default.
- W4220927418 cites W2122438081 @default.
- W4220927418 cites W2128551987 @default.
- W4220927418 cites W2132165075 @default.
- W4220927418 cites W2158333823 @default.
- W4220927418 cites W2170551349 @default.
- W4220927418 cites W2171111703 @default.
- W4220927418 cites W2171172082 @default.
- W4220927418 cites W2177432730 @default.
- W4220927418 cites W2179438025 @default.
- W4220927418 cites W2346768018 @default.
- W4220927418 cites W2406250479 @default.
- W4220927418 cites W2411489146 @default.
- W4220927418 cites W2412674201 @default.
- W4220927418 cites W2418024629 @default.
- W4220927418 cites W2509957998 @default.
- W4220927418 cites W2563914587 @default.
- W4220927418 cites W2750049634 @default.
- W4220927418 cites W2750416916 @default.
- W4220927418 cites W2800392236 @default.
- W4220927418 cites W2804581735 @default.
- W4220927418 cites W2805210233 @default.
- W4220927418 cites W2805619986 @default.
- W4220927418 cites W2806701851 @default.
- W4220927418 cites W2884964182 @default.
- W4220927418 cites W2889236955 @default.
- W4220927418 cites W2920191405 @default.
- W4220927418 cites W2950372712 @default.
- W4220927418 cites W2951516098 @default.
- W4220927418 cites W2965985232 @default.
- W4220927418 cites W2978143021 @default.
- W4220927418 cites W2984472267 @default.
- W4220927418 cites W2989744261 @default.
- W4220927418 cites W2991023348 @default.
- W4220927418 cites W3093858607 @default.
- W4220927418 cites W3106188259 @default.
- W4220927418 cites W3119445506 @default.
- W4220927418 cites W3123014124 @default.
- W4220927418 cites W3125088247 @default.
- W4220927418 cites W3131634425 @default.
- W4220927418 cites W3164692211 @default.
- W4220927418 doi "https://doi.org/10.1016/j.crmeth.2022.100188" @default.
- W4220927418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35463156" @default.
- W4220927418 hasPublicationYear "2022" @default.
- W4220927418 type Work @default.
- W4220927418 citedByCount "7" @default.
- W4220927418 countsByYear W42209274182022 @default.
- W4220927418 countsByYear W42209274182023 @default.
- W4220927418 crossrefType "journal-article" @default.
- W4220927418 hasAuthorship W4220927418A5014019530 @default.