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- W4220939901 abstract "To assess the feasibility of a prototype insulin infusion set (IIS) for extended wear in adults with type 1 diabetes.The prototype Capillary Biomedical investigational extended-wear IIS (CBX IIS) incorporates a soft, flexible, reinforced kink-resistant angled nylon-derivative cannula with one distal and three proximal ports to optimize insulin delivery. Twenty adult participants with type 1 diabetes established on insulin pump therapy used the CBX IIS for two 7-day test periods while wearing a Dexcom G5 continuous glucose monitor.Participants were able to wear the CBX IIS for an average of 6.6 ± 1.4 days. Eighty-eight percent (36 of 41) of sets were worn for 7 days. No serious adverse events were reported. Five infusion sets failed prematurely because of: unresolvable hyperglycaemia (three); hyperglycaemia with elevated ketones (one); or infection (one). Median time in range (3.9-10.0 mmol/L) was 62% (54-76). Average glucose levels per day of infusion set wear showed a statistically significant increase over time (p < .001).Our preliminary observations confirm the tolerability of the prototype CBX IIS for extended wear, albeit with a deterioration in glucose control after the third day." @default.
- W4220939901 created "2022-04-03" @default.
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- W4220939901 date "2022-03-18" @default.
- W4220939901 modified "2023-09-27" @default.
- W4220939901 title "Feasibility study of a prototype extended‐wear insulin infusion set in adults with type 1 diabetes" @default.
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- W4220939901 doi "https://doi.org/10.1111/dom.14685" @default.
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