Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220952161> ?p ?o ?g. }
- W4220952161 endingPage "850" @default.
- W4220952161 startingPage "835" @default.
- W4220952161 abstract "Identifying right ventricle (RV) abnormalities is important to stratifying pulmonary embolism (PE) severity. Disposition decisions are influenced by concerns about early deterioration. Triaging strategies, like the Simplified Pulmonary Embolism Severity Index (sPESI), do not include RV assessments as predictors or early deterioration as outcome(s). We aimed to (1) determine if RV assessment variables add prognostic accuracy for 5-day clinical deterioration in patients classified low risk by sPESI, and (2) determine the prognostic importance of RV assessments compared to other variables and to each other.We identified low risk sPESI patients (sPESI = 0) from a prospective PE registry. From a large field of candidate variables, we developed, and compared prognostic accuracy of, full and reduced random forest models (with and without RV assessment variables, respectively) on a validation database. We reported variable importance plots from full random forest and provided odds ratios for statistical inference of importance from multivariable logistic regression. Outcomes were death, cardiac arrest, hypotension, dysrhythmia, or respiratory failure within 5 days of PE.Of 1736 patients, 610 (35.1%) were low risk by sPESI and 72 (11.8%) experienced early deterioration. Of the 610, RV abnormality was present in 157 (25.7%) by CT, 121 (19.8%) by echocardiography, 132 (21.6%) by natriuretic peptide, and 107 (17.5%) by troponin. For deterioration, the receiver operating characteristics for full and reduced random forest prognostic models were 0.80 (0.77-0.82) and 0.71 (0.68-0.73), respectively. RV assessments were the top four in the variable importance plot for the random forest model. Echocardiography and CT significantly increased predicted probability of 5-day clinical deterioration by the multivariable logistic regression.A PE triaging strategy with RV imaging assessments had superior prognostic performance at classifying low risk for 5-day clinical deterioration versus one without." @default.
- W4220952161 created "2022-04-03" @default.
- W4220952161 creator A5007253076 @default.
- W4220952161 creator A5009004962 @default.
- W4220952161 creator A5011908317 @default.
- W4220952161 creator A5014494071 @default.
- W4220952161 creator A5016588269 @default.
- W4220952161 creator A5017799890 @default.
- W4220952161 creator A5018219007 @default.
- W4220952161 creator A5020148815 @default.
- W4220952161 creator A5021359596 @default.
- W4220952161 creator A5032236930 @default.
- W4220952161 creator A5056830894 @default.
- W4220952161 creator A5073008459 @default.
- W4220952161 creator A5078996791 @default.
- W4220952161 creator A5080383302 @default.
- W4220952161 creator A5082873606 @default.
- W4220952161 creator A5088490505 @default.
- W4220952161 date "2022-04-23" @default.
- W4220952161 modified "2023-10-07" @default.
- W4220952161 title "Can right ventricular assessments improve triaging of low risk pulmonary embolism?" @default.
- W4220952161 cites W1510311228 @default.
- W4220952161 cites W1606031635 @default.
- W4220952161 cites W1877085272 @default.
- W4220952161 cites W1963546277 @default.
- W4220952161 cites W1965400455 @default.
- W4220952161 cites W1976590154 @default.
- W4220952161 cites W1988254611 @default.
- W4220952161 cites W2023916064 @default.
- W4220952161 cites W2030571897 @default.
- W4220952161 cites W2064186732 @default.
- W4220952161 cites W2093274439 @default.
- W4220952161 cites W2102380178 @default.
- W4220952161 cites W2104207336 @default.
- W4220952161 cites W2117117885 @default.
- W4220952161 cites W2125707367 @default.
- W4220952161 cites W2131500858 @default.
- W4220952161 cites W2136576273 @default.
- W4220952161 cites W2140819416 @default.
- W4220952161 cites W2156917466 @default.
- W4220952161 cites W2233316475 @default.
- W4220952161 cites W2293336824 @default.
- W4220952161 cites W2328176404 @default.
- W4220952161 cites W2343249964 @default.
- W4220952161 cites W2400240907 @default.
- W4220952161 cites W2526809960 @default.
- W4220952161 cites W2534972948 @default.
- W4220952161 cites W2773645510 @default.
- W4220952161 cites W2774071133 @default.
- W4220952161 cites W2803777566 @default.
- W4220952161 cites W2897596918 @default.
- W4220952161 cites W2901061123 @default.
- W4220952161 cites W2905920407 @default.
- W4220952161 cites W2908088689 @default.
- W4220952161 cites W2971121646 @default.
- W4220952161 cites W2989714602 @default.
- W4220952161 cites W2991137419 @default.
- W4220952161 cites W3097454961 @default.
- W4220952161 cites W3173936357 @default.
- W4220952161 cites W3187989103 @default.
- W4220952161 cites W3189638887 @default.
- W4220952161 cites W3213577625 @default.
- W4220952161 cites W4205751478 @default.
- W4220952161 cites W4361868971 @default.
- W4220952161 doi "https://doi.org/10.1111/acem.14484" @default.
- W4220952161 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35289978" @default.
- W4220952161 hasPublicationYear "2022" @default.
- W4220952161 type Work @default.
- W4220952161 citedByCount "4" @default.
- W4220952161 countsByYear W42209521612022 @default.
- W4220952161 countsByYear W42209521612023 @default.
- W4220952161 crossrefType "journal-article" @default.
- W4220952161 hasAuthorship W4220952161A5007253076 @default.
- W4220952161 hasAuthorship W4220952161A5009004962 @default.
- W4220952161 hasAuthorship W4220952161A5011908317 @default.
- W4220952161 hasAuthorship W4220952161A5014494071 @default.
- W4220952161 hasAuthorship W4220952161A5016588269 @default.
- W4220952161 hasAuthorship W4220952161A5017799890 @default.
- W4220952161 hasAuthorship W4220952161A5018219007 @default.
- W4220952161 hasAuthorship W4220952161A5020148815 @default.
- W4220952161 hasAuthorship W4220952161A5021359596 @default.
- W4220952161 hasAuthorship W4220952161A5032236930 @default.
- W4220952161 hasAuthorship W4220952161A5056830894 @default.
- W4220952161 hasAuthorship W4220952161A5073008459 @default.
- W4220952161 hasAuthorship W4220952161A5078996791 @default.
- W4220952161 hasAuthorship W4220952161A5080383302 @default.
- W4220952161 hasAuthorship W4220952161A5082873606 @default.
- W4220952161 hasAuthorship W4220952161A5088490505 @default.
- W4220952161 hasConcept C126322002 @default.
- W4220952161 hasConcept C151956035 @default.
- W4220952161 hasConcept C156957248 @default.
- W4220952161 hasConcept C164705383 @default.
- W4220952161 hasConcept C194828623 @default.
- W4220952161 hasConcept C2776265017 @default.
- W4220952161 hasConcept C58471807 @default.
- W4220952161 hasConcept C71924100 @default.
- W4220952161 hasConceptScore W4220952161C126322002 @default.
- W4220952161 hasConceptScore W4220952161C151956035 @default.