Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220952913> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W4220952913 endingPage "1862" @default.
- W4220952913 startingPage "1856" @default.
- W4220952913 abstract "Abstract Background Donor and other differences mean understanding drivers of transplant survival for type 1 diabetics is challenging. We aimed to compare outcomes of simultaneous pancreas‐kidney transplant over kidney transplant alone for people with end‐stage kidney disease (ESKD) and type 1 diabetes. Methods We performed a population‐based cohort study comparing outcomes from kidney alone and kidney‐pancreas transplants using registry data. Our study population was people in Australia and New Zealand with type 1 diabetes and ESKD who received a kidney transplant in 1984–2016. Primary outcomes were time to kidney transplant failure and all‐cause death. Secondary outcomes were time to cardiovascular and non‐cardiovascular death. We compared adjusted survival using Cox regression (hazard ratio HR and 95% confidence intervals CI). Results Of 1295 type 1 diabetics receiving a transplant, 430 (33%) received deceased donor kidney, 172 (13%) received living donor kidney, and 693 (54%) received pancreas‐kidney transplant. Compared to deceased donor kidney, pancreas‐kidney recipients had 40% lower rate of kidney transplant failure (adjusted HR 0.60; 95% CI 0.45–0.81; p = 0.001) and 34% lower mortality (adjusted HR 0.66; 95% CI 0.53–0.83; p < 0.001), driven by 49% reduction in cardiovascular mortality (adjusted HR 0.51; 95% CI 0.36–0.72; p < 0.001). Pancreas‐kidney recipients had similar reductions in transplant failure and mortality compared to living kidney recipients, after adjusting for transplant timing. Conclusions For people with type 1 diabetes, pancreas‐kidney transplant provides improved transplant and overall survival compared to deceased donor kidney alone. Living donor kidneys may perform just as well as pancreas‐kidney transplant if waiting times are short." @default.
- W4220952913 created "2022-04-03" @default.
- W4220952913 creator A5039834479 @default.
- W4220952913 creator A5053547123 @default.
- W4220952913 creator A5058991365 @default.
- W4220952913 date "2022-03-30" @default.
- W4220952913 modified "2023-09-27" @default.
- W4220952913 title "Patient and kidney transplant survival in type 1 diabetics after kidney transplant alone compared to simultaneous pancreas‐kidney transplant" @default.
- W4220952913 cites W2017917282 @default.
- W4220952913 cites W2038981426 @default.
- W4220952913 cites W2059758156 @default.
- W4220952913 cites W2106271279 @default.
- W4220952913 cites W2753467455 @default.
- W4220952913 cites W3037342112 @default.
- W4220952913 cites W4301724356 @default.
- W4220952913 doi "https://doi.org/10.1111/ans.17663" @default.
- W4220952913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35352447" @default.
- W4220952913 hasPublicationYear "2022" @default.
- W4220952913 type Work @default.
- W4220952913 citedByCount "1" @default.
- W4220952913 countsByYear W42209529132023 @default.
- W4220952913 crossrefType "journal-article" @default.
- W4220952913 hasAuthorship W4220952913A5039834479 @default.
- W4220952913 hasAuthorship W4220952913A5053547123 @default.
- W4220952913 hasAuthorship W4220952913A5058991365 @default.
- W4220952913 hasBestOaLocation W42209529131 @default.
- W4220952913 hasConcept C126322002 @default.
- W4220952913 hasConcept C126894567 @default.
- W4220952913 hasConcept C134018914 @default.
- W4220952913 hasConcept C207103383 @default.
- W4220952913 hasConcept C2777180221 @default.
- W4220952913 hasConcept C2778653478 @default.
- W4220952913 hasConcept C2778764654 @default.
- W4220952913 hasConcept C2780091579 @default.
- W4220952913 hasConcept C2780303639 @default.
- W4220952913 hasConcept C2908647359 @default.
- W4220952913 hasConcept C44249647 @default.
- W4220952913 hasConcept C50382708 @default.
- W4220952913 hasConcept C555293320 @default.
- W4220952913 hasConcept C71924100 @default.
- W4220952913 hasConcept C99454951 @default.
- W4220952913 hasConceptScore W4220952913C126322002 @default.
- W4220952913 hasConceptScore W4220952913C126894567 @default.
- W4220952913 hasConceptScore W4220952913C134018914 @default.
- W4220952913 hasConceptScore W4220952913C207103383 @default.
- W4220952913 hasConceptScore W4220952913C2777180221 @default.
- W4220952913 hasConceptScore W4220952913C2778653478 @default.
- W4220952913 hasConceptScore W4220952913C2778764654 @default.
- W4220952913 hasConceptScore W4220952913C2780091579 @default.
- W4220952913 hasConceptScore W4220952913C2780303639 @default.
- W4220952913 hasConceptScore W4220952913C2908647359 @default.
- W4220952913 hasConceptScore W4220952913C44249647 @default.
- W4220952913 hasConceptScore W4220952913C50382708 @default.
- W4220952913 hasConceptScore W4220952913C555293320 @default.
- W4220952913 hasConceptScore W4220952913C71924100 @default.
- W4220952913 hasConceptScore W4220952913C99454951 @default.
- W4220952913 hasIssue "7-8" @default.
- W4220952913 hasLocation W42209529131 @default.
- W4220952913 hasLocation W42209529132 @default.
- W4220952913 hasLocation W42209529133 @default.
- W4220952913 hasOpenAccess W4220952913 @default.
- W4220952913 hasPrimaryLocation W42209529131 @default.
- W4220952913 hasRelatedWork W1727188710 @default.
- W4220952913 hasRelatedWork W1972357283 @default.
- W4220952913 hasRelatedWork W2088206352 @default.
- W4220952913 hasRelatedWork W2119154902 @default.
- W4220952913 hasRelatedWork W2133235702 @default.
- W4220952913 hasRelatedWork W2135028155 @default.
- W4220952913 hasRelatedWork W2203903734 @default.
- W4220952913 hasRelatedWork W2917746345 @default.
- W4220952913 hasRelatedWork W4200305071 @default.
- W4220952913 hasRelatedWork W4376871959 @default.
- W4220952913 hasVolume "92" @default.
- W4220952913 isParatext "false" @default.
- W4220952913 isRetracted "false" @default.
- W4220952913 workType "article" @default.