Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220956890> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4220956890 endingPage "751" @default.
- W4220956890 startingPage "750" @default.
- W4220956890 abstract "Influenza A viruses pose a challenge for vaccinology in their surface antigenic diversity; however, conserved internal proteins could be used to bolster cellular immunity to provide heterosubtypic immunity. Current influenza vaccines are founded on haemagglutinin antigenic match, and vaccine efficacy can be high when well matched, but more often the matching is subpar and unable to anticipate pandemic and outbreak strains. This shortfall has led to a call for the development of a universal influenza vaccine, 1 Erbelding EJ Post DJ Stemmy EJ et al. A universal influenza vaccine: the strategic plan for the National Institute of Allergy and Infectious Diseases. J Infect Dis. 2018; 218: 347-354 Crossref PubMed Scopus (232) Google Scholar which is proving difficult to accomplish. Efficacy and safety of a universal influenza A vaccine (MVA-NP+M1) in adults when given after seasonal quadrivalent influenza vaccine immunisation (FLU009): a phase 2b, randomised, double-blind trialMVA-NP+M1 was well tolerated with no vaccine-associated serious adverse events. A vaccine designed to induce moderate T-cell responses to the cross-reactive internal proteins of influenza A did not lead to improved incidence when given within 28 days after standard QIV immunisation. A greater magnitude of T-cell response with a different vaccine or regimen, or localisation in the lungs via alternative delivery, such as intranasal or aerosol, might be successful and require further investigation. Full-Text PDF" @default.
- W4220956890 created "2022-04-03" @default.
- W4220956890 creator A5036046953 @default.
- W4220956890 creator A5054554979 @default.
- W4220956890 date "2022-06-01" @default.
- W4220956890 modified "2023-10-14" @default.
- W4220956890 title "Universal influenza vaccines are futile when benchmarked against seasonal influenza vaccines" @default.
- W4220956890 cites W2072546058 @default.
- W4220956890 cites W2098337510 @default.
- W4220956890 cites W2105898497 @default.
- W4220956890 cites W2790722089 @default.
- W4220956890 cites W2966320012 @default.
- W4220956890 cites W2991314653 @default.
- W4220956890 cites W3011288462 @default.
- W4220956890 cites W3136996287 @default.
- W4220956890 cites W3187523027 @default.
- W4220956890 cites W4220793885 @default.
- W4220956890 doi "https://doi.org/10.1016/s1473-3099(21)00749-0" @default.
- W4220956890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35305315" @default.
- W4220956890 hasPublicationYear "2022" @default.
- W4220956890 type Work @default.
- W4220956890 citedByCount "1" @default.
- W4220956890 countsByYear W42209568902022 @default.
- W4220956890 crossrefType "journal-article" @default.
- W4220956890 hasAuthorship W4220956890A5036046953 @default.
- W4220956890 hasAuthorship W4220956890A5054554979 @default.
- W4220956890 hasConcept C133239900 @default.
- W4220956890 hasConcept C142724271 @default.
- W4220956890 hasConcept C159047783 @default.
- W4220956890 hasConcept C22070199 @default.
- W4220956890 hasConcept C2779134260 @default.
- W4220956890 hasConcept C2780689484 @default.
- W4220956890 hasConcept C3008058167 @default.
- W4220956890 hasConcept C3018751465 @default.
- W4220956890 hasConcept C524204448 @default.
- W4220956890 hasConcept C71924100 @default.
- W4220956890 hasConceptScore W4220956890C133239900 @default.
- W4220956890 hasConceptScore W4220956890C142724271 @default.
- W4220956890 hasConceptScore W4220956890C159047783 @default.
- W4220956890 hasConceptScore W4220956890C22070199 @default.
- W4220956890 hasConceptScore W4220956890C2779134260 @default.
- W4220956890 hasConceptScore W4220956890C2780689484 @default.
- W4220956890 hasConceptScore W4220956890C3008058167 @default.
- W4220956890 hasConceptScore W4220956890C3018751465 @default.
- W4220956890 hasConceptScore W4220956890C524204448 @default.
- W4220956890 hasConceptScore W4220956890C71924100 @default.
- W4220956890 hasIssue "6" @default.
- W4220956890 hasLocation W42209568901 @default.
- W4220956890 hasLocation W42209568902 @default.
- W4220956890 hasOpenAccess W4220956890 @default.
- W4220956890 hasPrimaryLocation W42209568901 @default.
- W4220956890 hasRelatedWork W2044687575 @default.
- W4220956890 hasRelatedWork W2048194595 @default.
- W4220956890 hasRelatedWork W2150125212 @default.
- W4220956890 hasRelatedWork W2767955000 @default.
- W4220956890 hasRelatedWork W2890492715 @default.
- W4220956890 hasRelatedWork W3198048121 @default.
- W4220956890 hasRelatedWork W4229375071 @default.
- W4220956890 hasRelatedWork W4231849058 @default.
- W4220956890 hasRelatedWork W4293102569 @default.
- W4220956890 hasRelatedWork W4318814642 @default.
- W4220956890 hasVolume "22" @default.
- W4220956890 isParatext "false" @default.
- W4220956890 isRetracted "false" @default.
- W4220956890 workType "article" @default.