FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220966977> ?p ?o ?g. }

• W4220966977 abstract "Coccidioidomycosis (Valley fever) is a disease caused by the fungal pathogens Coccidioides immitis and Coccidioides posadasii that are endemic to the southwestern United States and parts of Mexico and South America. Throughout the range where the pathogens are endemic, there are seasonal patterns of infection rates that are associated with certain climatic variables. Previous studies that looked at annual and monthly relationships of coccidioidomycosis and climate suggest that infection numbers are linked with precipitation and temperature fluctuations; however, these analytic methods may miss important nonlinear, nonmonotonic seasonal relationships between the response (Valley fever cases) and explanatory variables (climate) influencing disease outbreaks. To improve our current knowledge and to retest relationships, we used case data from three counties of high endemicity in southern Arizona paired with climate data to construct a generalized additive statistical model that explores which meteorological parameters are most useful in predicting Valley fever incidence throughout the year. We then use our model to forecast the pattern of Valley fever cases by month. Our model shows that maximum monthly temperature, average PM10, and total precipitation 1 month prior to reported cases (lagged model) were all significant in predicting Valley fever cases. Our model fits Valley fever case data in the region of endemicity of southern Arizona and captures the seasonal relationships that predict when the public is at higher risk of being infected. This study builds on and retests relationships described by previous studies regarding climate variables that are important for predicting risk of infection and understanding this fungal pathogen. IMPORTANCE The inhalation of environmental infectious propagules from the fungal pathogens Coccidioides immitis and Coccidioides posadasii by susceptible mammals can result in coccidioidomycosis (Valley fever). Arizona is known to be a region where the pathogen is hyperendemic, and reported cases are increasing throughout the western United States. Coccidioides spp. are naturally occurring fungi in arid soils. Little is known about ecological factors that influence the growth of these fungi, and a higher environmental burden may result in increases in human exposure and therefore case rates. By examining case and climate data from Arizona and using generalized additive statistical models, we were able to examine the relationship between disease outbreaks and climatic variables and predict seasonal time points of increased infection risk." @default.
• W4220966977 created "2022-04-03" @default.
• W4220966977 creator A5026470931 @default.
• W4220966977 creator A5029380534 @default.
• W4220966977 creator A5057134973 @default.
• W4220966977 date "2022-04-27" @default.
• W4220966977 modified "2023-09-26" @default.
• W4220966977 title "PM10 and Other Climatic Variables Are Important Predictors of Seasonal Variability of Coccidioidomycosis in Arizona" @default.
• W4220966977 cites W1572165214 @default.
• W4220966977 cites W1674880983 @default.
• W4220966977 cites W1813020586 @default.
• W4220966977 cites W1935547708 @default.
• W4220966977 cites W1979269769 @default.
• W4220966977 cites W1980078612 @default.
• W4220966977 cites W1982364996 @default.
• W4220966977 cites W2012303500 @default.
• W4220966977 cites W2019045964 @default.
• W4220966977 cites W2024355140 @default.
• W4220966977 cites W2025656342 @default.
• W4220966977 cites W2046906763 @default.
• W4220966977 cites W2066726286 @default.
• W4220966977 cites W2076132189 @default.
• W4220966977 cites W2081710608 @default.
• W4220966977 cites W2110747928 @default.
• W4220966977 cites W2113606869 @default.
• W4220966977 cites W2143083649 @default.
• W4220966977 cites W2150212288 @default.
• W4220966977 cites W2163777184 @default.
• W4220966977 cites W2170086004 @default.
• W4220966977 cites W2314078446 @default.
• W4220966977 cites W2341210203 @default.
• W4220966977 cites W2418182601 @default.
• W4220966977 cites W2571560814 @default.
• W4220966977 cites W2587328382 @default.
• W4220966977 cites W2606775993 @default.
• W4220966977 cites W2694401886 @default.
• W4220966977 cites W2743131688 @default.
• W4220966977 cites W2790899727 @default.
• W4220966977 cites W2792699090 @default.
• W4220966977 cites W2794190707 @default.
• W4220966977 cites W2884596317 @default.
• W4220966977 cites W2888481271 @default.
• W4220966977 cites W2889768818 @default.
• W4220966977 cites W2894870793 @default.
• W4220966977 cites W2913091535 @default.
• W4220966977 cites W2918555427 @default.
• W4220966977 cites W2947802409 @default.
• W4220966977 cites W2971719447 @default.
• W4220966977 cites W2973810576 @default.
• W4220966977 cites W2977947215 @default.
• W4220966977 cites W3002375224 @default.
• W4220966977 cites W3003348863 @default.
• W4220966977 cites W3041358129 @default.
• W4220966977 cites W3160076531 @default.
• W4220966977 cites W4226115197 @default.
• W4220966977 cites W4226145765 @default.
• W4220966977 cites W4251264506 @default.
• W4220966977 cites W4252506812 @default.
• W4220966977 doi "https://doi.org/10.1128/spectrum.01483-21" @default.
• W4220966977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35319247" @default.
• W4220966977 hasPublicationYear "2022" @default.
• W4220966977 type Work @default.
• W4220966977 citedByCount "5" @default.
• W4220966977 countsByYear W42209669772022 @default.
• W4220966977 countsByYear W42209669772023 @default.
• W4220966977 crossrefType "journal-article" @default.
• W4220966977 hasAuthorship W4220966977A5026470931 @default.
• W4220966977 hasAuthorship W4220966977A5029380534 @default.
• W4220966977 hasAuthorship W4220966977A5057134973 @default.
• W4220966977 hasBestOaLocation W42209669772 @default.
• W4220966977 hasConcept C107054158 @default.
• W4220966977 hasConcept C116675565 @default.
• W4220966977 hasConcept C125403950 @default.
• W4220966977 hasConcept C127313418 @default.
• W4220966977 hasConcept C144024400 @default.
• W4220966977 hasConcept C149923435 @default.
• W4220966977 hasConcept C153294291 @default.
• W4220966977 hasConcept C159047783 @default.
• W4220966977 hasConcept C18903297 @default.
• W4220966977 hasConcept C203014093 @default.
• W4220966977 hasConcept C205649164 @default.
• W4220966977 hasConcept C2778439347 @default.
• W4220966977 hasConcept C2781030883 @default.
• W4220966977 hasConcept C49204034 @default.
• W4220966977 hasConcept C86803240 @default.
• W4220966977 hasConcept C89423630 @default.
• W4220966977 hasConceptScore W4220966977C107054158 @default.
• W4220966977 hasConceptScore W4220966977C116675565 @default.
• W4220966977 hasConceptScore W4220966977C125403950 @default.
• W4220966977 hasConceptScore W4220966977C127313418 @default.
• W4220966977 hasConceptScore W4220966977C144024400 @default.
• W4220966977 hasConceptScore W4220966977C149923435 @default.
• W4220966977 hasConceptScore W4220966977C153294291 @default.
• W4220966977 hasConceptScore W4220966977C159047783 @default.
• W4220966977 hasConceptScore W4220966977C18903297 @default.
• W4220966977 hasConceptScore W4220966977C203014093 @default.
• W4220966977 hasConceptScore W4220966977C205649164 @default.
• W4220966977 hasConceptScore W4220966977C2778439347 @default.
• W4220966977 hasConceptScore W4220966977C2781030883 @default.
• W4220966977 hasConceptScore W4220966977C49204034 @default.

• next