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- W4220975556 abstract "Nuclear pore complexes (NPCs) embedded within the nuclear envelope mediate rapid, selective, and bidirectional traffic between the cytoplasm and the nucleoplasm. The human NPC scaffold consists of a pair of ∼100 nm diameter rings separated by ∼50 nm. Hundreds of largely intrinsically disordered polypeptides attached to this scaffold generate the permeability barrier and provide binding sites for cargo complexes undergoing transport. Deciphering the mechanism and dynamics of this process is challenged by the need for high spatial and temporal resolution." @default.
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- W4220975556 date "2022-02-01" @default.
- W4220975556 modified "2023-09-26" @default.
- W4220975556 title "Super resolved 3D tracking of cargo transport through nuclear pore complexes" @default.
- W4220975556 doi "https://doi.org/10.1016/j.bpj.2021.11.2030" @default.
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