FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220977462> ?p ?o ?g. }

• W4220977462 endingPage "e0265240" @default.
• W4220977462 startingPage "e0265240" @default.
• W4220977462 abstract "Mental disorders are associated with markedly reduced life expectancy, in part due to an increased risk of death due to infection, likely reflecting sepsis-associated mortality. Patients with mental disorders are at an increased risk of sepsis, but data on the prognostic impact of mental disorders in sepsis are sparse, showing conflicting findings.We used statewide data to identify hospitalizations aged ≥18 years with sepsis in Texas during 2014-2017. Mental disorders, including mood, anxiety, psychosis, and personality disorders were identified using Clinical Classification Software codes. Multilevel, multivariable logistic regression with propensity adjustment (primary model), with propensity score matching, and multivariable logistic regression as alternative models, were used to estimate the association between mental disorders and short-term mortality (defined as in-hospital mortality or discharge to hospice). Additional models were fitted for sensitivity analyses and to estimate the prognostic associations of individual categories of mental disorders.Among 283,025 hospitalizations with sepsis, 56,904 (20.1%) had mental disorders. Hospitalizations with vs without mental disorders were younger (age 18-44 years 12.2% vs 10.6%), more commonly white (61.0% vs 49.8%), with lower burden of comorbidities (mean [SD] Deyo comorbidity index 2.53 [2.27] vs 2.73 [2.47]), and with lower need for organ support (mechanical ventilation 32.8% vs 36.0%); p<0.0001 for all comparisons. Crude short-term mortality among sepsis hospitalizations with and without mental disorders was 25.0% vs 32.8%, respectively. On adjusted analyses, mental disorders remained associated with lower odds of short-term mortality (adjusted odds ratio 0.792 [95% CI 0.772-0.812]). This finding was consistent on the alternative modeling approaches, sensitivity analyses, and examination of individual categories of mental disorders.Mental disorders were associated, unexpectedly, with markedly lower risk of short-term mortality in sepsis. Further studies to examine the mechanisms underlying these findings may inform future efforts to improve sepsis outcomes." @default.
• W4220977462 created "2022-04-03" @default.
• W4220977462 creator A5040774952 @default.
• W4220977462 creator A5088652197 @default.
• W4220977462 date "2022-03-10" @default.
• W4220977462 modified "2023-09-26" @default.
• W4220977462 title "Impact of history of mental disorders on short-term mortality among hospitalized patients with sepsis: A population-based cohort study" @default.
• W4220977462 cites W12094253 @default.
• W4220977462 cites W1606893964 @default.
• W4220977462 cites W1763837731 @default.
• W4220977462 cites W177009488 @default.
• W4220977462 cites W1869842011 @default.
• W4220977462 cites W1967278969 @default.
• W4220977462 cites W1972396486 @default.
• W4220977462 cites W1984542705 @default.
• W4220977462 cites W1987785379 @default.
• W4220977462 cites W1992868687 @default.
• W4220977462 cites W1993714448 @default.
• W4220977462 cites W1994289493 @default.
• W4220977462 cites W1997908175 @default.
• W4220977462 cites W2000321839 @default.
• W4220977462 cites W2011944029 @default.
• W4220977462 cites W2015329932 @default.
• W4220977462 cites W2022420916 @default.
• W4220977462 cites W2029670080 @default.
• W4220977462 cites W2049927822 @default.
• W4220977462 cites W2053158626 @default.
• W4220977462 cites W2061326496 @default.
• W4220977462 cites W2075107167 @default.
• W4220977462 cites W2087969867 @default.
• W4220977462 cites W2097572674 @default.
• W4220977462 cites W2102094268 @default.
• W4220977462 cites W2106239116 @default.
• W4220977462 cites W2108344016 @default.
• W4220977462 cites W2111635289 @default.
• W4220977462 cites W2113216986 @default.
• W4220977462 cites W2121656227 @default.
• W4220977462 cites W2127567394 @default.
• W4220977462 cites W2143104764 @default.
• W4220977462 cites W2144387798 @default.
• W4220977462 cites W2145066257 @default.
• W4220977462 cites W2145577370 @default.
• W4220977462 cites W2151101205 @default.
• W4220977462 cites W2154926042 @default.
• W4220977462 cites W2161821256 @default.
• W4220977462 cites W2170285826 @default.
• W4220977462 cites W2186789877 @default.
• W4220977462 cites W2280404143 @default.
• W4220977462 cites W2303203998 @default.
• W4220977462 cites W2399060753 @default.
• W4220977462 cites W2423582068 @default.
• W4220977462 cites W2506702796 @default.
• W4220977462 cites W2512644059 @default.
• W4220977462 cites W2517170026 @default.
• W4220977462 cites W2580206093 @default.
• W4220977462 cites W2584247552 @default.
• W4220977462 cites W2588924761 @default.
• W4220977462 cites W2599076725 @default.
• W4220977462 cites W2617016860 @default.
• W4220977462 cites W2755626276 @default.
• W4220977462 cites W2761422859 @default.
• W4220977462 cites W2789512708 @default.
• W4220977462 cites W2806558699 @default.
• W4220977462 cites W2809244390 @default.
• W4220977462 cites W2889770461 @default.
• W4220977462 cites W2901929987 @default.
• W4220977462 cites W2912654919 @default.
• W4220977462 cites W2913715064 @default.
• W4220977462 cites W2914443670 @default.
• W4220977462 cites W2921715866 @default.
• W4220977462 cites W2924419587 @default.
• W4220977462 cites W2945988913 @default.
• W4220977462 cites W2964215777 @default.
• W4220977462 cites W2969535997 @default.
• W4220977462 cites W2981747116 @default.
• W4220977462 cites W2985316494 @default.
• W4220977462 cites W2994279493 @default.
• W4220977462 cites W2998853022 @default.
• W4220977462 cites W3000602238 @default.
• W4220977462 cites W3005797804 @default.
• W4220977462 cites W3032376321 @default.
• W4220977462 cites W3035005996 @default.
• W4220977462 cites W3039999871 @default.
• W4220977462 cites W3093501122 @default.
• W4220977462 cites W3113940964 @default.
• W4220977462 cites W3159677833 @default.
• W4220977462 cites W4248429808 @default.
• W4220977462 doi "https://doi.org/10.1371/journal.pone.0265240" @default.
• W4220977462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35271683" @default.
• W4220977462 hasPublicationYear "2022" @default.
• W4220977462 type Work @default.
• W4220977462 citedByCount "3" @default.
• W4220977462 countsByYear W42209774622023 @default.
• W4220977462 crossrefType "journal-article" @default.
• W4220977462 hasAuthorship W4220977462A5040774952 @default.
• W4220977462 hasAuthorship W4220977462A5088652197 @default.
• W4220977462 hasBestOaLocation W42209774621 @default.
• W4220977462 hasConcept C118552586 @default.

• next