Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220978312> ?p ?o ?g. }
- W4220978312 abstract "Cortical actin plays a key role in cell movement and division, but has also been implicated in the organisation of cell surface receptors such as G protein-coupled receptors. The actin mesh proximal to the inner membrane forms small fenced regions, or 'corrals', in which receptors can be constrained. Quantification of the actin mesh at the nanoscale has largely been attempted in single molecule datasets and electron micrographs. This work describes the development and validation of workflows for analysis of super resolved fixed cortical actin images obtained by Super Resolved Radial Fluctuations (SRRF), Structured Illumination Microscopy (3D-SIM) and Expansion Microscopy (ExM). SRRF analysis was used to show a significant increase in corral area when treating cells with the actin disrupting agent cytochalasin D (increase of 0.31 µm2 ± 0.04 SEM), and ExM analysis allowed for the quantitation of actin filament densities. Thus, this work allows complex actin networks to be quantified from super-resolved images and is amenable to both fixed and live cell imaging." @default.
- W4220978312 created "2022-04-03" @default.
- W4220978312 creator A5015346833 @default.
- W4220978312 creator A5028272194 @default.
- W4220978312 creator A5042191140 @default.
- W4220978312 creator A5070048387 @default.
- W4220978312 date "2022-02-17" @default.
- W4220978312 modified "2023-10-18" @default.
- W4220978312 title "Simple methods for quantifying super-resolved cortical actin" @default.
- W4220978312 cites W2034713721 @default.
- W4220978312 cites W2035098726 @default.
- W4220978312 cites W2047320699 @default.
- W4220978312 cites W2055862760 @default.
- W4220978312 cites W2109281145 @default.
- W4220978312 cites W2114656957 @default.
- W4220978312 cites W2119632652 @default.
- W4220978312 cites W2122782850 @default.
- W4220978312 cites W2167279371 @default.
- W4220978312 cites W2269415927 @default.
- W4220978312 cites W2299243614 @default.
- W4220978312 cites W2460281481 @default.
- W4220978312 cites W2512505748 @default.
- W4220978312 cites W2575251549 @default.
- W4220978312 cites W2619744772 @default.
- W4220978312 cites W2668309208 @default.
- W4220978312 cites W2766290879 @default.
- W4220978312 cites W2788997417 @default.
- W4220978312 cites W2805577390 @default.
- W4220978312 cites W2811141606 @default.
- W4220978312 cites W2884507765 @default.
- W4220978312 cites W2887081644 @default.
- W4220978312 cites W2966311990 @default.
- W4220978312 cites W2971690534 @default.
- W4220978312 cites W3005450702 @default.
- W4220978312 cites W3007549840 @default.
- W4220978312 cites W3012401333 @default.
- W4220978312 cites W3015871332 @default.
- W4220978312 cites W3025012329 @default.
- W4220978312 cites W3081075888 @default.
- W4220978312 cites W3093822659 @default.
- W4220978312 cites W3151179921 @default.
- W4220978312 doi "https://doi.org/10.1038/s41598-022-06702-w" @default.
- W4220978312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35177729" @default.
- W4220978312 hasPublicationYear "2022" @default.
- W4220978312 type Work @default.
- W4220978312 citedByCount "9" @default.
- W4220978312 countsByYear W42209783122022 @default.
- W4220978312 countsByYear W42209783122023 @default.
- W4220978312 crossrefType "journal-article" @default.
- W4220978312 hasAuthorship W4220978312A5015346833 @default.
- W4220978312 hasAuthorship W4220978312A5028272194 @default.
- W4220978312 hasAuthorship W4220978312A5042191140 @default.
- W4220978312 hasAuthorship W4220978312A5070048387 @default.
- W4220978312 hasBestOaLocation W42209783121 @default.
- W4220978312 hasConcept C120665830 @default.
- W4220978312 hasConcept C121332964 @default.
- W4220978312 hasConcept C12554922 @default.
- W4220978312 hasConcept C125705527 @default.
- W4220978312 hasConcept C14228908 @default.
- W4220978312 hasConcept C142669718 @default.
- W4220978312 hasConcept C147080431 @default.
- W4220978312 hasConcept C1491633281 @default.
- W4220978312 hasConcept C170493617 @default.
- W4220978312 hasConcept C185592680 @default.
- W4220978312 hasConcept C2775995422 @default.
- W4220978312 hasConcept C2776041460 @default.
- W4220978312 hasConcept C2993400109 @default.
- W4220978312 hasConcept C55493867 @default.
- W4220978312 hasConcept C86803240 @default.
- W4220978312 hasConcept C95444343 @default.
- W4220978312 hasConceptScore W4220978312C120665830 @default.
- W4220978312 hasConceptScore W4220978312C121332964 @default.
- W4220978312 hasConceptScore W4220978312C12554922 @default.
- W4220978312 hasConceptScore W4220978312C125705527 @default.
- W4220978312 hasConceptScore W4220978312C14228908 @default.
- W4220978312 hasConceptScore W4220978312C142669718 @default.
- W4220978312 hasConceptScore W4220978312C147080431 @default.
- W4220978312 hasConceptScore W4220978312C1491633281 @default.
- W4220978312 hasConceptScore W4220978312C170493617 @default.
- W4220978312 hasConceptScore W4220978312C185592680 @default.
- W4220978312 hasConceptScore W4220978312C2775995422 @default.
- W4220978312 hasConceptScore W4220978312C2776041460 @default.
- W4220978312 hasConceptScore W4220978312C2993400109 @default.
- W4220978312 hasConceptScore W4220978312C55493867 @default.
- W4220978312 hasConceptScore W4220978312C86803240 @default.
- W4220978312 hasConceptScore W4220978312C95444343 @default.
- W4220978312 hasIssue "1" @default.
- W4220978312 hasLocation W42209783121 @default.
- W4220978312 hasLocation W42209783122 @default.
- W4220978312 hasLocation W42209783123 @default.
- W4220978312 hasLocation W42209783124 @default.
- W4220978312 hasLocation W42209783125 @default.
- W4220978312 hasLocation W42209783126 @default.
- W4220978312 hasLocation W42209783127 @default.
- W4220978312 hasOpenAccess W4220978312 @default.
- W4220978312 hasPrimaryLocation W42209783121 @default.
- W4220978312 hasRelatedWork W1994109845 @default.
- W4220978312 hasRelatedWork W2004952942 @default.
- W4220978312 hasRelatedWork W2018466181 @default.
- W4220978312 hasRelatedWork W2028918491 @default.