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- W4220990553 startingPage "1650" @default.
- W4220990553 abstract "Anaplastic large cell lymphoma (ALCL) is an uncommon type of non-Hodgkin's lymphoma (NHL), as well as one of the subtypes of T cell lymphoma, accounting for 1 to 3% of non-Hodgkin's lymphomas and around 15% of T cell lymphomas. In 2016, the World Health Organization (WHO) classified anaplastic large cell lymphoma into four categories: ALK-positive ALCL (ALK+ALCL), ALK-negative ALCL (ALK-ALCL), primary cutaneous ALCL (pcALCL), and breast-implant-associated ALCL (BIA-ALCL), respectively. Clinical symptoms, gene changes, prognoses, and therapy differ among the four types. Large lymphoid cells with copious cytoplasm and pleomorphic characteristics with horseshoe-shaped or reniform nuclei, for example, are found in both ALK+ and ALK-ALCL. However, their epidemiology and pathogenetic origins are distinct. BIA-ALCL is currently recognized as a new provisional entity, which is a noninvasive disease with favorable results. In this review, we focus on molecular pathogenesis and management of anaplastic large cell lymphoma." @default.
- W4220990553 created "2022-04-03" @default.
- W4220990553 creator A5008452010 @default.
- W4220990553 creator A5040120871 @default.
- W4220990553 creator A5064382500 @default.
- W4220990553 creator A5085803998 @default.
- W4220990553 date "2022-03-24" @default.
- W4220990553 modified "2023-10-01" @default.
- W4220990553 title "Anaplastic Large Cell Lymphoma: Molecular Pathogenesis and Treatment" @default.
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