FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220992079> ?p ?o ?g. }

• W4220992079 endingPage "1062" @default.
• W4220992079 startingPage "1055" @default.
• W4220992079 abstract "Objective Current generation left ventricular assist devices (LVADs) operate with a fixed rotation speed and no automated speed adjustment function. This study evaluates the concept of physiological pump speed optimisation based on aortic valve opening (AVO) imaging during a cardiopulmonary exercise test (CPET). Methods This prospective crossover study ( NCT05063006 ) enrolled patients with implanted third-generation LVADs with hydrodynamic bearing. After resting speed optimisation, patients were randomised to a fixed-modified speed or modified-fixed speed CPET sequence. Fixed speed CPET maintained baseline pump settings. During the modified speed CPET, the LVAD speed was continuously altered to preserve periodic AVO. Results We included 22 patients, the mean age was 58.4±7 years, 4.5% were women and 54.5% had ischaemic cardiomyopathy. Exertional AVO assessment was feasible in all subjects. Maintaining periodic AVO allowed to safely raise the pump speed from 2900 (IQR 2640–3000) to 3440 revolutions per minute (RPM) (IQR 3100–3700; p<0.001). As a result, peak oxygen consumption increased from 11.1±2.4 to 12.8±2.8 mL/kg/min (p<0.001) and maximum workload from 1.1 (IQR 0.9–1.5) to 1.2 W/kg (IQR 0.9–1.7; p=0.028). The Borg scale exertion level decreased from 15.2±1.5 to 13.5±1.2 (p=0.005). Conclusions Transthoracic AVO imaging is possible during CPETs in patients with LVAD. Dynamic echo-guided pump speed adjustment based on the AVO improves exercise tolerance and augments peak oxygen consumption and maximum workload." @default.
• W4220992079 created "2022-04-03" @default.
• W4220992079 creator A5002726900 @default.
• W4220992079 creator A5007999411 @default.
• W4220992079 creator A5027629334 @default.
• W4220992079 creator A5036997744 @default.
• W4220992079 creator A5038263353 @default.
• W4220992079 creator A5045345143 @default.
• W4220992079 creator A5055249590 @default.
• W4220992079 creator A5056027719 @default.
• W4220992079 creator A5069182559 @default.
• W4220992079 creator A5069437624 @default.
• W4220992079 creator A5086851497 @default.
• W4220992079 date "2022-03-21" @default.
• W4220992079 modified "2023-10-03" @default.
• W4220992079 title "Echo-guided left ventricular assist device speed optimisation for exercise maximisation" @default.
• W4220992079 cites W1540803598 @default.
• W4220992079 cites W1545907120 @default.
• W4220992079 cites W1592743208 @default.
• W4220992079 cites W1621439407 @default.
• W4220992079 cites W1839711436 @default.
• W4220992079 cites W1897246540 @default.
• W4220992079 cites W1972152625 @default.
• W4220992079 cites W1989327827 @default.
• W4220992079 cites W2006096328 @default.
• W4220992079 cites W2021416545 @default.
• W4220992079 cites W2022882519 @default.
• W4220992079 cites W2024859961 @default.
• W4220992079 cites W2094351246 @default.
• W4220992079 cites W2101765353 @default.
• W4220992079 cites W2228121314 @default.
• W4220992079 cites W2264334943 @default.
• W4220992079 cites W2325476221 @default.
• W4220992079 cites W2369073832 @default.
• W4220992079 cites W2398136863 @default.
• W4220992079 cites W2467522255 @default.
• W4220992079 cites W2786400801 @default.
• W4220992079 cites W2889383415 @default.
• W4220992079 cites W2899358703 @default.
• W4220992079 cites W2972779160 @default.
• W4220992079 cites W3005475808 @default.
• W4220992079 cites W3007438931 @default.
• W4220992079 cites W3011369792 @default.
• W4220992079 cites W3108548404 @default.
• W4220992079 cites W3123035356 @default.
• W4220992079 cites W610139672 @default.
• W4220992079 doi "https://doi.org/10.1136/heartjnl-2021-320495" @default.
• W4220992079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35314453" @default.
• W4220992079 hasPublicationYear "2022" @default.
• W4220992079 type Work @default.
• W4220992079 citedByCount "4" @default.
• W4220992079 countsByYear W42209920792022 @default.
• W4220992079 countsByYear W42209920792023 @default.
• W4220992079 crossrefType "journal-article" @default.
• W4220992079 hasAuthorship W4220992079A5002726900 @default.
• W4220992079 hasAuthorship W4220992079A5007999411 @default.
• W4220992079 hasAuthorship W4220992079A5027629334 @default.
• W4220992079 hasAuthorship W4220992079A5036997744 @default.
• W4220992079 hasAuthorship W4220992079A5038263353 @default.
• W4220992079 hasAuthorship W4220992079A5045345143 @default.
• W4220992079 hasAuthorship W4220992079A5055249590 @default.
• W4220992079 hasAuthorship W4220992079A5056027719 @default.
• W4220992079 hasAuthorship W4220992079A5069182559 @default.
• W4220992079 hasAuthorship W4220992079A5069437624 @default.
• W4220992079 hasAuthorship W4220992079A5086851497 @default.
• W4220992079 hasBestOaLocation W42209920791 @default.
• W4220992079 hasConcept C126322002 @default.
• W4220992079 hasConcept C142724271 @default.
• W4220992079 hasConcept C164705383 @default.
• W4220992079 hasConcept C204787440 @default.
• W4220992079 hasConcept C27081682 @default.
• W4220992079 hasConcept C2775932942 @default.
• W4220992079 hasConcept C2778198053 @default.
• W4220992079 hasConcept C2993376042 @default.
• W4220992079 hasConcept C71924100 @default.
• W4220992079 hasConcept C78085059 @default.
• W4220992079 hasConcept C87813604 @default.
• W4220992079 hasConceptScore W4220992079C126322002 @default.
• W4220992079 hasConceptScore W4220992079C142724271 @default.
• W4220992079 hasConceptScore W4220992079C164705383 @default.
• W4220992079 hasConceptScore W4220992079C204787440 @default.
• W4220992079 hasConceptScore W4220992079C27081682 @default.
• W4220992079 hasConceptScore W4220992079C2775932942 @default.
• W4220992079 hasConceptScore W4220992079C2778198053 @default.
• W4220992079 hasConceptScore W4220992079C2993376042 @default.
• W4220992079 hasConceptScore W4220992079C71924100 @default.
• W4220992079 hasConceptScore W4220992079C78085059 @default.
• W4220992079 hasConceptScore W4220992079C87813604 @default.
• W4220992079 hasIssue "13" @default.
• W4220992079 hasLocation W42209920791 @default.
• W4220992079 hasLocation W42209920792 @default.
• W4220992079 hasLocation W42209920793 @default.
• W4220992079 hasOpenAccess W4220992079 @default.
• W4220992079 hasPrimaryLocation W42209920791 @default.
• W4220992079 hasRelatedWork W1971300170 @default.
• W4220992079 hasRelatedWork W2004513006 @default.
• W4220992079 hasRelatedWork W2057388958 @default.
• W4220992079 hasRelatedWork W2082900536 @default.

• next