Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220995794> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4220995794 endingPage "595" @default.
- W4220995794 startingPage "593" @default.
- W4220995794 abstract "Objectives: Tumors of the gastrointestinal tract (GIST) are the most commonly seen tumors of the gut. The current study aimed to evaluate the clinical and pathological features of gastrointestinal stromal tumors presented in our setting. Methodology: A prospective observational study was conducted at a tertiary care center, Pakistan between January 2019 to March 2021. All cases of duodenal and stomach gastrointestinal stromal tumors diagnosed and treated at our center were analyzed in our study. All clinicopathological tumors including patient characteristics, treatments, histological examinations, and Genomic mutation were documented. The clinicopathologic parameters were compared between stomach and duodenal GIST. Results: A total of 221 patients were enrolled in the study. The majority were below the age of sixty years. The male to female ratio was 0.97. The most common presenting symptom was active bleeding or severe anemia with a frequency of 114 (51.6%). The majority of the duodenal GIST were present in the descending portion. 147 (66.5%) patients were offered limited resection while 25.8% were offered pancreaticoduodenectomy, and the remainder were not operated. About 30 (13.6%) patients had genetic mutation. Of these, the majority had a KIT mutation. In four patients, KIT and PDGFRA were both mutated. We stratified the patients with respect to the clinicopathological factors and found that tumor size was significantly associated with duodenal GIST (p<0.001). Tumor size of > 10 cm was more frequently found in duodenum than stomach >10 [26 (11.8%) vs. 21 (6.7%)]. Conclusion: The present study highlights the clinicopathological pattern of GIST in our population. Furthermore, it indicated that the tumor size was significantly greater in patients diagnosed with duodenal GIST as compared to stomach GIST. Keywords: Duodenum, GIST, gastrointestinal stromal tumors, stomach adenocarcinoma" @default.
- W4220995794 created "2022-04-03" @default.
- W4220995794 creator A5003310587 @default.
- W4220995794 creator A5012338315 @default.
- W4220995794 creator A5038667970 @default.
- W4220995794 creator A5051357761 @default.
- W4220995794 creator A5061087180 @default.
- W4220995794 creator A5072883847 @default.
- W4220995794 date "2022-02-26" @default.
- W4220995794 modified "2023-10-01" @default.
- W4220995794 title "Clinicopathological Study of Duodenal Gastrointestinal Stromal Tumors (GIST)" @default.
- W4220995794 doi "https://doi.org/10.53350/pjmhs22162593" @default.
- W4220995794 hasPublicationYear "2022" @default.
- W4220995794 type Work @default.
- W4220995794 citedByCount "1" @default.
- W4220995794 countsByYear W42209957942023 @default.
- W4220995794 crossrefType "journal-article" @default.
- W4220995794 hasAuthorship W4220995794A5003310587 @default.
- W4220995794 hasAuthorship W4220995794A5012338315 @default.
- W4220995794 hasAuthorship W4220995794A5038667970 @default.
- W4220995794 hasAuthorship W4220995794A5051357761 @default.
- W4220995794 hasAuthorship W4220995794A5061087180 @default.
- W4220995794 hasAuthorship W4220995794A5072883847 @default.
- W4220995794 hasBestOaLocation W42209957941 @default.
- W4220995794 hasConcept C126322002 @default.
- W4220995794 hasConcept C16930146 @default.
- W4220995794 hasConcept C2775922572 @default.
- W4220995794 hasConcept C2776809568 @default.
- W4220995794 hasConcept C2777007597 @default.
- W4220995794 hasConcept C2778764654 @default.
- W4220995794 hasConcept C2778975757 @default.
- W4220995794 hasConcept C2779422922 @default.
- W4220995794 hasConcept C2780512811 @default.
- W4220995794 hasConcept C2781357019 @default.
- W4220995794 hasConcept C37307934 @default.
- W4220995794 hasConcept C71924100 @default.
- W4220995794 hasConcept C90924648 @default.
- W4220995794 hasConceptScore W4220995794C126322002 @default.
- W4220995794 hasConceptScore W4220995794C16930146 @default.
- W4220995794 hasConceptScore W4220995794C2775922572 @default.
- W4220995794 hasConceptScore W4220995794C2776809568 @default.
- W4220995794 hasConceptScore W4220995794C2777007597 @default.
- W4220995794 hasConceptScore W4220995794C2778764654 @default.
- W4220995794 hasConceptScore W4220995794C2778975757 @default.
- W4220995794 hasConceptScore W4220995794C2779422922 @default.
- W4220995794 hasConceptScore W4220995794C2780512811 @default.
- W4220995794 hasConceptScore W4220995794C2781357019 @default.
- W4220995794 hasConceptScore W4220995794C37307934 @default.
- W4220995794 hasConceptScore W4220995794C71924100 @default.
- W4220995794 hasConceptScore W4220995794C90924648 @default.
- W4220995794 hasIssue "2" @default.
- W4220995794 hasLocation W42209957941 @default.
- W4220995794 hasOpenAccess W4220995794 @default.
- W4220995794 hasPrimaryLocation W42209957941 @default.
- W4220995794 hasRelatedWork W1757867860 @default.
- W4220995794 hasRelatedWork W1967465354 @default.
- W4220995794 hasRelatedWork W2069892760 @default.
- W4220995794 hasRelatedWork W2401691442 @default.
- W4220995794 hasRelatedWork W2418654049 @default.
- W4220995794 hasRelatedWork W2898279973 @default.
- W4220995794 hasRelatedWork W3032296308 @default.
- W4220995794 hasRelatedWork W4220995794 @default.
- W4220995794 hasRelatedWork W4285244020 @default.
- W4220995794 hasRelatedWork W3093610334 @default.
- W4220995794 hasVolume "16" @default.
- W4220995794 isParatext "false" @default.
- W4220995794 isRetracted "false" @default.
- W4220995794 workType "article" @default.