FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4220998519> ?p ?o ?g. }

• W4220998519 endingPage "11" @default.
• W4220998519 startingPage "1" @default.
• W4220998519 abstract "Background and Aim. The relationship between liver fibrosis scores and clinical outcomes in patients with COVID-19 is not compressively assessed. Methods. We identified relevant cohort studies that assessed the relationship between liver fibrosis scores (e.g., FIB-4, NAFLD fibrosis score (NFS), and aspartate aminotransferase to platelet ratio index (APRI)) and associated prognosis outcomes by searching the PubMed, EMBASE, and medRxiv databases. The potential dose-response effect was performed using a stage robust error meta-regression. Results. Sixteen studies with 8,736 hospitalized patients with COVID-19 were included. One-point score in FIB-4 increase was significantly associated with increased mechanical ventilation (RR: 2.23, 95% CI: 1.37–3.65, <math xmlns=http://www.w3.org/1998/Math/MathML id=M1> <mi>P</mi> <mo>=</mo> <mn>0.001</mn> </math> ), severe COVID-19 (RR: 1.82, 95% CI: 1.53–2.16, <math xmlns=http://www.w3.org/1998/Math/MathML id=M2> <mi>P</mi> <mo><</mo> <mn>0.001</mn> </math> ), and death (RR: 1.47, 95% CI: 1.31–1.65, <math xmlns=http://www.w3.org/1998/Math/MathML id=M3> <mi>P</mi> <mo><</mo> <mn>0.001</mn> </math> ), rather than hospitalization (RR: 1.35, 95% CI: 0.72–2.56, <math xmlns=http://www.w3.org/1998/Math/MathML id=M4> <mi>P</mi> <mo>=</mo> <mn>0.35</mn> </math> ). Furthermore, there is a significant positive linear relationship between FIB-4 and severe COVID-19 ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M5> <msub> <mrow> <mi>P</mi> </mrow> <mrow> <mtext>nonlinearity</mtext> </mrow> </msub> <mo>=</mo> <mn>0.12</mn> </math> ) and mortality ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M6> <msub> <mrow> <mi>P</mi> </mrow> <mrow> <mtext>nonlinearity</mtext> </mrow> </msub> <mo>=</mo> <mn>0.18</mn> </math> ). Regarding other liver scores, one unit elevation in APRI increased the risk of death by 178% (RR: 2.78, 95% CI: 1.10–6.99, <math xmlns=http://www.w3.org/1998/Math/MathML id=M7> <mi>P</mi> <mo>=</mo> <mn>0.03</mn> </math> ). Higher NFS (≥−1.5) and Forns index were associated with increased risk of severe COVID-19 and COVID-19-associated death. Conclusion. Our dose-response meta-analysis suggests high liver fibrosis scores are associated with worse prognosis in patients with COVID-19. For patients with COVID-19 at admission, especially for those with coexisting chronic liver diseases, assessment of liver fibrosis scores might be useful for identifying high risk of developing severe COVID-19 cases and worse outcomes." @default.
• W4220998519 created "2022-04-03" @default.
• W4220998519 creator A5005555710 @default.
• W4220998519 creator A5021905069 @default.
• W4220998519 creator A5031276674 @default.
• W4220998519 creator A5041868590 @default.
• W4220998519 creator A5045909868 @default.
• W4220998519 creator A5069013621 @default.
• W4220998519 creator A5071349641 @default.
• W4220998519 creator A5078990142 @default.
• W4220998519 creator A5083387463 @default.
• W4220998519 date "2022-03-29" @default.
• W4220998519 modified "2023-10-18" @default.
• W4220998519 title "Liver Fibrosis Scores and Hospitalization, Mechanical Ventilation, Severity, and Death in Patients with COVID-19: A Systematic Review and Dose-Response Meta-Analysis" @default.
• W4220998519 cites W1889367418 @default.
• W4220998519 cites W2118655749 @default.
• W4220998519 cites W2529917894 @default.
• W4220998519 cites W2588592564 @default.
• W4220998519 cites W2771459593 @default.
• W4220998519 cites W2771935284 @default.
• W4220998519 cites W2785758228 @default.
• W4220998519 cites W2885825937 @default.
• W4220998519 cites W2889014241 @default.
• W4220998519 cites W2893835498 @default.
• W4220998519 cites W2951531415 @default.
• W4220998519 cites W2987595848 @default.
• W4220998519 cites W2996552247 @default.
• W4220998519 cites W3016151265 @default.
• W4220998519 cites W3021302768 @default.
• W4220998519 cites W3024577853 @default.
• W4220998519 cites W3024773709 @default.
• W4220998519 cites W3029819826 @default.
• W4220998519 cites W3036289929 @default.
• W4220998519 cites W3038175434 @default.
• W4220998519 cites W3041099585 @default.
• W4220998519 cites W3042070402 @default.
• W4220998519 cites W3045671639 @default.
• W4220998519 cites W3047375053 @default.
• W4220998519 cites W3080686928 @default.
• W4220998519 cites W3085434206 @default.
• W4220998519 cites W3087677084 @default.
• W4220998519 cites W3092361867 @default.
• W4220998519 cites W3093974232 @default.
• W4220998519 cites W3095484986 @default.
• W4220998519 cites W3096009574 @default.
• W4220998519 cites W3097013616 @default.
• W4220998519 cites W3100097255 @default.
• W4220998519 cites W3103539547 @default.
• W4220998519 cites W3114703458 @default.
• W4220998519 cites W3115240882 @default.
• W4220998519 cites W3118615836 @default.
• W4220998519 cites W3131381393 @default.
• W4220998519 cites W3132595318 @default.
• W4220998519 cites W3158693961 @default.
• W4220998519 cites W3158809374 @default.
• W4220998519 cites W3168008035 @default.
• W4220998519 cites W3174381542 @default.
• W4220998519 cites W3174763534 @default.
• W4220998519 cites W3183820984 @default.
• W4220998519 cites W4225646929 @default.
• W4220998519 cites W4226464530 @default.
• W4220998519 doi "https://doi.org/10.1155/2022/7235860" @default.
• W4220998519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35369116" @default.
• W4220998519 hasPublicationYear "2022" @default.
• W4220998519 type Work @default.
• W4220998519 citedByCount "10" @default.
• W4220998519 countsByYear W42209985192022 @default.
• W4220998519 countsByYear W42209985192023 @default.
• W4220998519 crossrefType "journal-article" @default.
• W4220998519 hasAuthorship W4220998519A5005555710 @default.
• W4220998519 hasAuthorship W4220998519A5021905069 @default.
• W4220998519 hasAuthorship W4220998519A5031276674 @default.
• W4220998519 hasAuthorship W4220998519A5041868590 @default.
• W4220998519 hasAuthorship W4220998519A5045909868 @default.
• W4220998519 hasAuthorship W4220998519A5069013621 @default.
• W4220998519 hasAuthorship W4220998519A5071349641 @default.
• W4220998519 hasAuthorship W4220998519A5078990142 @default.
• W4220998519 hasAuthorship W4220998519A5083387463 @default.
• W4220998519 hasBestOaLocation W42209985191 @default.
• W4220998519 hasConcept C11413529 @default.
• W4220998519 hasConcept C126322002 @default.
• W4220998519 hasConcept C2777080012 @default.
• W4220998519 hasConcept C2779134260 @default.
• W4220998519 hasConcept C2780559512 @default.
• W4220998519 hasConcept C3008058167 @default.
• W4220998519 hasConcept C33923547 @default.
• W4220998519 hasConcept C44249647 @default.
• W4220998519 hasConcept C524204448 @default.
• W4220998519 hasConcept C71924100 @default.
• W4220998519 hasConcept C90924648 @default.
• W4220998519 hasConcept C95190672 @default.
• W4220998519 hasConceptScore W4220998519C11413529 @default.
• W4220998519 hasConceptScore W4220998519C126322002 @default.
• W4220998519 hasConceptScore W4220998519C2777080012 @default.
• W4220998519 hasConceptScore W4220998519C2779134260 @default.
• W4220998519 hasConceptScore W4220998519C2780559512 @default.
• W4220998519 hasConceptScore W4220998519C3008058167 @default.
• W4220998519 hasConceptScore W4220998519C33923547 @default.

• next