Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221003025> ?p ?o ?g. }
- W4221003025 endingPage "251" @default.
- W4221003025 startingPage "251" @default.
- W4221003025 abstract "The neurotoxic alkaloid β-N-methyl-amino-l-alanine (BMAA) and related isomers, including N-(2-aminoethyl glycine) (AEG), β-amino-N-methyl alanine (BAMA), and 2,4-diaminobutyric acid (DAB), have been reported previously in cyanobacterial samples. However, there are conflicting reports regarding their occurrence in surface waters. In this study, we evaluated the impact of amending lake water samples with trichloroacetic acid (0.1 M TCA) on the detection of BMAA isomers, compared with pre-existing protocols. A sensitive instrumental method was enlisted for the survey, with limits of detection in the range of 5−10 ng L−1. Higher detection rates and significantly greater levels (paired Wilcoxon’s signed-rank tests, p < 0.001) of BMAA isomers were observed in TCA-amended samples (method B) compared to samples without TCA (method A). The overall range of B/A ratios was 0.67−8.25 for AEG (up to +725%) and 0.69−15.5 for DAB (up to +1450%), with absolute concentration increases in TCA-amended samples of up to +15,000 ng L−1 for AEG and +650 ng L−1 for DAB. We also documented the trends in the occurrence of BMAA isomers for a large breadth of field-collected lakes from Brazil, Canada, France, Mexico, and the United Kingdom. Data gathered during this overarching campaign (overall, n = 390 within 45 lake sampling sites) indicated frequent detections of AEG and DAB isomers, with detection rates of 30% and 43% and maximum levels of 19,000 ng L−1 and 1100 ng L−1, respectively. In contrast, BAMA was found in less than 8% of the water samples, and BMAA was not found in any sample. These results support the analyses of free-living cyanobacteria, wherein BMAA was often reported at concentrations of 2−4 orders of magnitude lower than AEG and DAB. Seasonal measurements conducted at two bloom-impacted lakes indicated limited correlations of BMAA isomers with total microcystins or chlorophyll-a, which deserves further investigation." @default.
- W4221003025 created "2022-04-03" @default.
- W4221003025 creator A5003172054 @default.
- W4221003025 creator A5006414792 @default.
- W4221003025 creator A5008480394 @default.
- W4221003025 creator A5020050392 @default.
- W4221003025 creator A5020150244 @default.
- W4221003025 creator A5023632838 @default.
- W4221003025 creator A5027642064 @default.
- W4221003025 creator A5030670440 @default.
- W4221003025 creator A5032585874 @default.
- W4221003025 creator A5039124661 @default.
- W4221003025 creator A5042570468 @default.
- W4221003025 creator A5043898068 @default.
- W4221003025 creator A5055218047 @default.
- W4221003025 creator A5059636038 @default.
- W4221003025 creator A5062352659 @default.
- W4221003025 creator A5077764215 @default.
- W4221003025 creator A5088869333 @default.
- W4221003025 date "2022-03-31" @default.
- W4221003025 modified "2023-10-18" @default.
- W4221003025 title "Occurrence of BMAA Isomers in Bloom-Impacted Lakes and Reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom" @default.
- W4221003025 cites W1125015531 @default.
- W4221003025 cites W1971449188 @default.
- W4221003025 cites W1983820834 @default.
- W4221003025 cites W1992114982 @default.
- W4221003025 cites W1995883365 @default.
- W4221003025 cites W1998626588 @default.
- W4221003025 cites W2017159295 @default.
- W4221003025 cites W2017798140 @default.
- W4221003025 cites W2017958497 @default.
- W4221003025 cites W2023109480 @default.
- W4221003025 cites W2025842590 @default.
- W4221003025 cites W2035246073 @default.
- W4221003025 cites W2049255279 @default.
- W4221003025 cites W2060281968 @default.
- W4221003025 cites W2070995531 @default.
- W4221003025 cites W2073230346 @default.
- W4221003025 cites W2131101804 @default.
- W4221003025 cites W2139217432 @default.
- W4221003025 cites W2141651003 @default.
- W4221003025 cites W2256966024 @default.
- W4221003025 cites W2281619210 @default.
- W4221003025 cites W2342419965 @default.
- W4221003025 cites W2406562495 @default.
- W4221003025 cites W2607043746 @default.
- W4221003025 cites W2684200317 @default.
- W4221003025 cites W2740819879 @default.
- W4221003025 cites W2742524206 @default.
- W4221003025 cites W2758246424 @default.
- W4221003025 cites W2773293697 @default.
- W4221003025 cites W2788125551 @default.
- W4221003025 cites W2790635258 @default.
- W4221003025 cites W2794863648 @default.
- W4221003025 cites W2800165160 @default.
- W4221003025 cites W2886440472 @default.
- W4221003025 cites W2895587316 @default.
- W4221003025 cites W2899476493 @default.
- W4221003025 cites W2912831478 @default.
- W4221003025 cites W2964733322 @default.
- W4221003025 cites W2966522617 @default.
- W4221003025 cites W2974876980 @default.
- W4221003025 cites W2990276589 @default.
- W4221003025 cites W2995445062 @default.
- W4221003025 cites W3004653076 @default.
- W4221003025 cites W3038335573 @default.
- W4221003025 cites W3105953276 @default.
- W4221003025 cites W3110151170 @default.
- W4221003025 cites W3124354971 @default.
- W4221003025 cites W4211010233 @default.
- W4221003025 doi "https://doi.org/10.3390/toxins14040251" @default.
- W4221003025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35448860" @default.
- W4221003025 hasPublicationYear "2022" @default.
- W4221003025 type Work @default.
- W4221003025 citedByCount "4" @default.
- W4221003025 countsByYear W42210030252022 @default.
- W4221003025 countsByYear W42210030252023 @default.
- W4221003025 crossrefType "journal-article" @default.
- W4221003025 hasAuthorship W4221003025A5003172054 @default.
- W4221003025 hasAuthorship W4221003025A5006414792 @default.
- W4221003025 hasAuthorship W4221003025A5008480394 @default.
- W4221003025 hasAuthorship W4221003025A5020050392 @default.
- W4221003025 hasAuthorship W4221003025A5020150244 @default.
- W4221003025 hasAuthorship W4221003025A5023632838 @default.
- W4221003025 hasAuthorship W4221003025A5027642064 @default.
- W4221003025 hasAuthorship W4221003025A5030670440 @default.
- W4221003025 hasAuthorship W4221003025A5032585874 @default.
- W4221003025 hasAuthorship W4221003025A5039124661 @default.
- W4221003025 hasAuthorship W4221003025A5042570468 @default.
- W4221003025 hasAuthorship W4221003025A5043898068 @default.
- W4221003025 hasAuthorship W4221003025A5055218047 @default.
- W4221003025 hasAuthorship W4221003025A5059636038 @default.
- W4221003025 hasAuthorship W4221003025A5062352659 @default.
- W4221003025 hasAuthorship W4221003025A5077764215 @default.
- W4221003025 hasAuthorship W4221003025A5088869333 @default.
- W4221003025 hasBestOaLocation W42210030251 @default.
- W4221003025 hasConcept C107872376 @default.
- W4221003025 hasConcept C119128265 @default.