Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221009615> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4221009615 endingPage "304" @default.
- W4221009615 startingPage "301" @default.
- W4221009615 abstract "The published results of the post-marketing ORAL Surveillance study, which compared the Janus kinase (JAK) inhibitor tofacitinib with anti-TNF therapy in older patients with rheumatoid arthritis who have cardiovascular risk factors, have led to changes in the recommendations for the use of JAK inhibitors. Although new safety signals have emerged for tofacitinib, namely malignancy and cardiovascular disease, it should be noted that these signals are relative to those seen with TNF blockers. The new data further raise our intrigue that venous thromboembolism might be a true risk related to JAK inhibition. Reassuringly, the totality of the findings from this newly published study and the other data collected to date suggest that JAK inhibitors can be used safely at approved doses by many patients with rheumatoid arthritis. In this Perspective article, the authors discuss the results of the post-marketing ORAL Surveillance study comparing the safety of the JAK inhibitor tofacitinib and TNF inhibition in patients with rheumatoid arthritis, as well as the potential implications for clinical practice." @default.
- W4221009615 created "2022-04-03" @default.
- W4221009615 creator A5006070255 @default.
- W4221009615 creator A5057538503 @default.
- W4221009615 date "2022-03-22" @default.
- W4221009615 modified "2023-10-10" @default.
- W4221009615 title "Oral surveillance and JAK inhibitor safety: the theory of relativity" @default.
- W4221009615 cites W1599185368 @default.
- W4221009615 cites W2114872119 @default.
- W4221009615 cites W2218477436 @default.
- W4221009615 cites W2921889468 @default.
- W4221009615 cites W2971086071 @default.
- W4221009615 cites W2982670354 @default.
- W4221009615 cites W3030828222 @default.
- W4221009615 cites W3094882380 @default.
- W4221009615 cites W3097773625 @default.
- W4221009615 cites W3126579487 @default.
- W4221009615 cites W3135932408 @default.
- W4221009615 cites W3139515949 @default.
- W4221009615 cites W3167197477 @default.
- W4221009615 cites W3210178764 @default.
- W4221009615 cites W4205998736 @default.
- W4221009615 cites W4210529991 @default.
- W4221009615 cites W4226280844 @default.
- W4221009615 doi "https://doi.org/10.1038/s41584-022-00767-7" @default.
- W4221009615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35318462" @default.
- W4221009615 hasPublicationYear "2022" @default.
- W4221009615 type Work @default.
- W4221009615 citedByCount "55" @default.
- W4221009615 countsByYear W42210096152022 @default.
- W4221009615 countsByYear W42210096152023 @default.
- W4221009615 crossrefType "journal-article" @default.
- W4221009615 hasAuthorship W4221009615A5006070255 @default.
- W4221009615 hasAuthorship W4221009615A5057538503 @default.
- W4221009615 hasBestOaLocation W42210096151 @default.
- W4221009615 hasConcept C112392421 @default.
- W4221009615 hasConcept C126322002 @default.
- W4221009615 hasConcept C12713177 @default.
- W4221009615 hasConcept C143998085 @default.
- W4221009615 hasConcept C154945302 @default.
- W4221009615 hasConcept C16005928 @default.
- W4221009615 hasConcept C177713679 @default.
- W4221009615 hasConcept C2776233030 @default.
- W4221009615 hasConcept C2777077863 @default.
- W4221009615 hasConcept C2777575956 @default.
- W4221009615 hasConcept C2778690821 @default.
- W4221009615 hasConcept C2778886723 @default.
- W4221009615 hasConcept C41008148 @default.
- W4221009615 hasConcept C71924100 @default.
- W4221009615 hasConceptScore W4221009615C112392421 @default.
- W4221009615 hasConceptScore W4221009615C126322002 @default.
- W4221009615 hasConceptScore W4221009615C12713177 @default.
- W4221009615 hasConceptScore W4221009615C143998085 @default.
- W4221009615 hasConceptScore W4221009615C154945302 @default.
- W4221009615 hasConceptScore W4221009615C16005928 @default.
- W4221009615 hasConceptScore W4221009615C177713679 @default.
- W4221009615 hasConceptScore W4221009615C2776233030 @default.
- W4221009615 hasConceptScore W4221009615C2777077863 @default.
- W4221009615 hasConceptScore W4221009615C2777575956 @default.
- W4221009615 hasConceptScore W4221009615C2778690821 @default.
- W4221009615 hasConceptScore W4221009615C2778886723 @default.
- W4221009615 hasConceptScore W4221009615C41008148 @default.
- W4221009615 hasConceptScore W4221009615C71924100 @default.
- W4221009615 hasIssue "5" @default.
- W4221009615 hasLocation W42210096151 @default.
- W4221009615 hasLocation W42210096152 @default.
- W4221009615 hasLocation W42210096153 @default.
- W4221009615 hasOpenAccess W4221009615 @default.
- W4221009615 hasPrimaryLocation W42210096151 @default.
- W4221009615 hasRelatedWork W142197995 @default.
- W4221009615 hasRelatedWork W1948265060 @default.
- W4221009615 hasRelatedWork W2132809463 @default.
- W4221009615 hasRelatedWork W2333162414 @default.
- W4221009615 hasRelatedWork W2340001399 @default.
- W4221009615 hasRelatedWork W2752345645 @default.
- W4221009615 hasRelatedWork W2755978387 @default.
- W4221009615 hasRelatedWork W2916556513 @default.
- W4221009615 hasRelatedWork W3085086630 @default.
- W4221009615 hasRelatedWork W3145529239 @default.
- W4221009615 hasVolume "18" @default.
- W4221009615 isParatext "false" @default.
- W4221009615 isRetracted "false" @default.
- W4221009615 workType "article" @default.