FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221015649> ?p ?o ?g. }

• W4221015649 abstract "Molecular profile of breast cancer in Latin-American women was studied in five countries: Argentina, Brazil, Chile, Mexico, and Uruguay. Data about socioeconomic characteristics, risk factors, prognostic factors, and molecular subtypes were described, and the 60-month overall cumulative survival probabilities (OS) were estimated. From 2011 to 2013, 1,300 eligible Latin-American women 18 years or older, with a diagnosis of breast cancer in clinical stage II or III, and performance status ≦̸1 were invited to participate in a prospective cohort study. Face-to-face interviews were conducted, and clinical and outcome data, including death, were extracted from medical records. Unadjusted associations were evaluated by Chi-squared and Fisher’s exact tests and the OS by Kaplan–Meier method. Log-rank test was used to determine differences between cumulative probability curves. Multivariable adjustment was carried out by entering potential confounders in the Cox regression model. The OS at 60 months was 83.9%. Multivariable-adjusted death hazard differences were found for women living in Argentina (2.27), Chile (1.95), and Uruguay (2.42) compared with Mexican women, for older (≥60 years) (1.84) compared with younger (≤40 years) women, for basal-like subtype (5.8), luminal B (2.43), and HER2-enriched (2.52) compared with luminal A subtype, and for tumor clinical stages IIB (1.91), IIIA (3.54), and IIIB (3.94) compared with stage IIA women. OS was associated with country of residence, PAM50 intrinsic subtype, age, and tumor stage at diagnosis. While the latter is known to be influenced by access to care, including cancer screening, timely diagnosis and treatment, including access to more effective treatment protocols, it may also influence epigenetic changes that, potentially, impact molecular subtypes. Data derived from heretofore understudied populations with unique geographic ancestry and sociocultural experiences are critical to furthering our understanding of this complexity." @default.
• W4221015649 created "2022-04-03" @default.
• W4221015649 creator A5000578713 @default.
• W4221015649 creator A5000644688 @default.
• W4221015649 creator A5000745622 @default.
• W4221015649 creator A5001072752 @default.
• W4221015649 creator A5001150230 @default.
• W4221015649 creator A5001487695 @default.
• W4221015649 creator A5001845025 @default.
• W4221015649 creator A5002059215 @default.
• W4221015649 creator A5002104438 @default.
• W4221015649 creator A5002200778 @default.
• W4221015649 creator A5002334947 @default.
• W4221015649 creator A5002437307 @default.
• W4221015649 creator A5002548433 @default.
• W4221015649 creator A5002984938 @default.
• W4221015649 creator A5002995320 @default.
• W4221015649 creator A5003676270 @default.
• W4221015649 creator A5003737911 @default.
• W4221015649 creator A5003858753 @default.
• W4221015649 creator A5004737680 @default.
• W4221015649 creator A5005002828 @default.
• W4221015649 creator A5005321474 @default.
• W4221015649 creator A5005751462 @default.
• W4221015649 creator A5006344517 @default.
• W4221015649 creator A5007020947 @default.
• W4221015649 creator A5007142305 @default.
• W4221015649 creator A5008081060 @default.
• W4221015649 creator A5009026621 @default.
• W4221015649 creator A5009161530 @default.
• W4221015649 creator A5009680452 @default.
• W4221015649 creator A5010247784 @default.
• W4221015649 creator A5010594518 @default.
• W4221015649 creator A5010763891 @default.
• W4221015649 creator A5011385272 @default.
• W4221015649 creator A5011492370 @default.
• W4221015649 creator A5011882866 @default.
• W4221015649 creator A5012638489 @default.
• W4221015649 creator A5012684981 @default.
• W4221015649 creator A5012731480 @default.
• W4221015649 creator A5013274805 @default.
• W4221015649 creator A5013400974 @default.
• W4221015649 creator A5013903864 @default.
• W4221015649 creator A5013985862 @default.
• W4221015649 creator A5014213653 @default.
• W4221015649 creator A5014272421 @default.
• W4221015649 creator A5014321403 @default.
• W4221015649 creator A5014423779 @default.
• W4221015649 creator A5014548944 @default.
• W4221015649 creator A5014783593 @default.
• W4221015649 creator A5014825905 @default.
• W4221015649 creator A5015703504 @default.
• W4221015649 creator A5016100299 @default.
• W4221015649 creator A5016208921 @default.
• W4221015649 creator A5016826358 @default.
• W4221015649 creator A5016917063 @default.
• W4221015649 creator A5017389237 @default.
• W4221015649 creator A5017602758 @default.
• W4221015649 creator A5017686615 @default.
• W4221015649 creator A5017726940 @default.
• W4221015649 creator A5017739438 @default.
• W4221015649 creator A5017817876 @default.
• W4221015649 creator A5018305633 @default.
• W4221015649 creator A5018720764 @default.
• W4221015649 creator A5018790940 @default.
• W4221015649 creator A5019212502 @default.
• W4221015649 creator A5019524079 @default.
• W4221015649 creator A5019849014 @default.
• W4221015649 creator A5020242869 @default.
• W4221015649 creator A5020398539 @default.
• W4221015649 creator A5020525223 @default.
• W4221015649 creator A5020637051 @default.
• W4221015649 creator A5021048809 @default.
• W4221015649 creator A5021455109 @default.
• W4221015649 creator A5021655338 @default.
• W4221015649 creator A5022495667 @default.
• W4221015649 creator A5022933882 @default.
• W4221015649 creator A5024561143 @default.
• W4221015649 creator A5024973148 @default.
• W4221015649 creator A5025538352 @default.
• W4221015649 creator A5025582733 @default.
• W4221015649 creator A5026067732 @default.
• W4221015649 creator A5026077271 @default.
• W4221015649 creator A5026301798 @default.
• W4221015649 creator A5026386803 @default.
• W4221015649 creator A5026777870 @default.
• W4221015649 creator A5027111627 @default.
• W4221015649 creator A5027521438 @default.
• W4221015649 creator A5027677885 @default.
• W4221015649 creator A5028123130 @default.
• W4221015649 creator A5028335195 @default.
• W4221015649 creator A5028982208 @default.
• W4221015649 creator A5028998184 @default.
• W4221015649 creator A5029433710 @default.
• W4221015649 creator A5029797801 @default.
• W4221015649 creator A5029875483 @default.
• W4221015649 creator A5030147813 @default.
• W4221015649 creator A5030728347 @default.
• W4221015649 creator A5031074838 @default.
• W4221015649 creator A5031130836 @default.

• next