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- W4221022280 abstract "Lateral gene transfer (LGT) facilitates many processes in bacterial ecology and pathogenesis, especially regarding pathogen evolution and the spread of antibiotic resistance across species. The obligate intracellular chlamydiae, which cause a range of diseases in humans and animals, were historically thought to be highly deficient in this process. However, research over the past few decades has demonstrated that this was not the case. The first reports of homologous recombination in the Chlamydiaceae family were published in the early 1990s. Later, the advent of whole-genome sequencing uncovered clear evidence for LGT in the evolution of the Chlamydiaceae , although the acquisition of tetracycline resistance in Chlamydia (C.) suis is the only recent instance of interphylum LGT. In contrast, genome and in vitro studies have shown that intraspecies DNA exchange occurs frequently and can even cross species barriers between closely related chlamydiae, such as between C. trachomatis , C. muridarum , and C. suis . Additionally, whole-genome analysis led to the identification of various DNA repair and recombination systems in C. trachomatis , but the exact machinery of DNA uptake and homologous recombination in the chlamydiae has yet to be fully elucidated. Here, we reviewed the current state of knowledge concerning LGT in Chlamydia by focusing on the effect of homologous recombination on the chlamydial genome, the recombination machinery, and its potential as a genetic tool for Chlamydia." @default.
- W4221022280 created "2022-04-03" @default.
- W4221022280 creator A5056061919 @default.
- W4221022280 creator A5081508064 @default.
- W4221022280 creator A5081751244 @default.
- W4221022280 date "2022-03-07" @default.
- W4221022280 modified "2023-09-30" @default.
- W4221022280 title "The Impact of Lateral Gene Transfer in Chlamydia" @default.
- W4221022280 cites W1783779827 @default.
- W4221022280 cites W1911376021 @default.
- W4221022280 cites W1977890732 @default.
- W4221022280 cites W1985068526 @default.
- W4221022280 cites W1993562154 @default.
- W4221022280 cites W1998485402 @default.
- W4221022280 cites W2026850911 @default.
- W4221022280 cites W2032562388 @default.
- W4221022280 cites W2034054997 @default.
- W4221022280 cites W2039978286 @default.
- W4221022280 cites W2042055876 @default.
- W4221022280 cites W2042767778 @default.
- W4221022280 cites W2047326257 @default.
- W4221022280 cites W2053079494 @default.
- W4221022280 cites W2053292987 @default.
- W4221022280 cites W2054120191 @default.
- W4221022280 cites W2054648936 @default.
- W4221022280 cites W2054939407 @default.
- W4221022280 cites W2063062111 @default.
- W4221022280 cites W2066879086 @default.
- W4221022280 cites W2077269211 @default.
- W4221022280 cites W2082499478 @default.
- W4221022280 cites W2085543266 @default.
- W4221022280 cites W2087420229 @default.
- W4221022280 cites W2094235298 @default.
- W4221022280 cites W2106635287 @default.
- W4221022280 cites W2109478863 @default.
- W4221022280 cites W2114593800 @default.
- W4221022280 cites W2115140994 @default.
- W4221022280 cites W2115780677 @default.
- W4221022280 cites W2116052426 @default.
- W4221022280 cites W2118453530 @default.
- W4221022280 cites W2118871658 @default.
- W4221022280 cites W2119864387 @default.
- W4221022280 cites W2120419610 @default.
- W4221022280 cites W2125304134 @default.
- W4221022280 cites W2130634584 @default.
- W4221022280 cites W2141041292 @default.
- W4221022280 cites W2142880699 @default.
- W4221022280 cites W2146288037 @default.
- W4221022280 cites W2153891511 @default.
- W4221022280 cites W2153946434 @default.
- W4221022280 cites W2154541074 @default.
- W4221022280 cites W2155417707 @default.
- W4221022280 cites W2157672734 @default.
- W4221022280 cites W2161339747 @default.
- W4221022280 cites W2161621941 @default.
- W4221022280 cites W2164567662 @default.
- W4221022280 cites W2168896194 @default.
- W4221022280 cites W2170551597 @default.
- W4221022280 cites W2172604359 @default.
- W4221022280 cites W2179708451 @default.
- W4221022280 cites W2259151740 @default.
- W4221022280 cites W2266060744 @default.
- W4221022280 cites W2313418643 @default.
- W4221022280 cites W2321266700 @default.
- W4221022280 cites W2332232022 @default.
- W4221022280 cites W2398964796 @default.
- W4221022280 cites W2417174404 @default.
- W4221022280 cites W2492187830 @default.
- W4221022280 cites W2512427890 @default.
- W4221022280 cites W2524786991 @default.
- W4221022280 cites W2559410061 @default.
- W4221022280 cites W2593666742 @default.
- W4221022280 cites W2610304054 @default.
- W4221022280 cites W2614451828 @default.
- W4221022280 cites W2622934429 @default.
- W4221022280 cites W2623366409 @default.
- W4221022280 cites W2763532277 @default.
- W4221022280 cites W2806412809 @default.
- W4221022280 cites W2895747738 @default.
- W4221022280 cites W2896918722 @default.
- W4221022280 cites W2954881746 @default.
- W4221022280 cites W2966309307 @default.
- W4221022280 cites W2973043909 @default.
- W4221022280 cites W2973063509 @default.
- W4221022280 cites W2981607390 @default.
- W4221022280 cites W2981774759 @default.
- W4221022280 cites W2988237307 @default.
- W4221022280 cites W3080179126 @default.
- W4221022280 cites W3174430459 @default.
- W4221022280 cites W3176627386 @default.
- W4221022280 cites W3211189706 @default.
- W4221022280 cites W4200015580 @default.
- W4221022280 doi "https://doi.org/10.3389/fcimb.2022.861899" @default.
- W4221022280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35321311" @default.
- W4221022280 hasPublicationYear "2022" @default.
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