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- W4221025534 abstract "8-Aminoquinolines are the building blocks of many pharmaceutical compounds, which has motivated the scientific community to develop new ways to derivatize these compounds. In this work, we performed a site-selective C5-H and N-H alkylation of 8-aminoquinolines using para-quinone methides under extremely mild conditions. C5-H alkylation was performed using protecting group-free 8-aminoquinolines and in metal-free conditions. N-H alkylations were also carried out under mild conditions. All corresponding alkylation products were obtained in high to excellent yields." @default.
- W4221025534 created "2022-04-03" @default.
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- W4221025534 date "2022-01-01" @default.
- W4221025534 modified "2023-10-11" @default.
- W4221025534 title "Site-selective C5–H and <i>N</i>–H alkylation of unprotected 8-aminoquinolines" @default.
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- W4221025534 doi "https://doi.org/10.1039/d2cc00780k" @default.
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