FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221027466> ?p ?o ?g. }

• W4221027466 abstract "Studies on the association between urinary protein-to-creatinine ratio (UPCR) and chronic kidney disease (CKD) progression are limited. This study aimed to investigate the relationship between UPCR and CKD progression in a Japanese population.The present research was a secondary analysis of a prospective cohort study. Eight hundred and ninety-six subjects from the research of CKD-ROUTE in Japan were included. All the patients were new visitors or first referred to the participating centers of nephrology between October 2010 and December 2011. The target-independent variable was UPCR measured at baseline. The dependent variable was CKD progression and the estimated glomerular filtration rate (eGFR) changes during follow-up. We used Cox proportional hazards regression to investigate the association between UPCR and CKD progression risk. To address UPCR and CKD progression's non-linearity, a multivariate Cox proportional hazards regression analysis with cubic spline functions model and smooth curve fitting (penalized spline method) were conducted. We further used a generalized linear mixed model to explore the relationship between UPCR and the changes of eGFR.The mean age of the included patients was 67.2 ± 13.4 years old. Two hundred and thirty-four people occurred CKD progression during follow-up. The present study showed that UPCR was independently associated with CKD progression in the multivariate analysis [HR = 1.164, 95% CI (1.116, 1.215)]. The non-linear relationship between UPCR and CKD progression was explored in a dose-dependent manner, with an obvious inflection point of 1.699. Furthermore, our findings indicated that the tendency of the effect sizes on both the left and right sides of the inflection point was not consistent [left HR: 4.377, 95% CI (2.956, 6.483); right HR: 1.100, 95% CI (1.049-1.153)]. Using the linear mixed-effects regression model, we found that UPCR was an independent predictor of the longitudinal changes in eGFR (p < 0.001 for the interaction term with time).This study demonstrates a nonlinear positive relationship between UPCR and CKD progression in the Japanese population. UPCR is also an independent predictor of the longitudinal changes in eGFR." @default.
• W4221027466 created "2022-04-03" @default.
• W4221027466 creator A5011331009 @default.
• W4221027466 creator A5024792434 @default.
• W4221027466 creator A5036202917 @default.
• W4221027466 creator A5056053058 @default.
• W4221027466 creator A5057620126 @default.
• W4221027466 creator A5083753979 @default.
• W4221027466 date "2022-03-31" @default.
• W4221027466 modified "2023-10-10" @default.
• W4221027466 title "Association Between Urinary Protein-to-Creatinine Ratio and Chronic Kidney Disease Progression: A Secondary Analysis of a Prospective Cohort Study" @default.
• W4221027466 cites W1544667273 @default.
• W4221027466 cites W1913814900 @default.
• W4221027466 cites W1978593002 @default.
• W4221027466 cites W1983568514 @default.
• W4221027466 cites W1992543573 @default.
• W4221027466 cites W2009826896 @default.
• W4221027466 cites W2041085272 @default.
• W4221027466 cites W2061758692 @default.
• W4221027466 cites W2065497432 @default.
• W4221027466 cites W2068797907 @default.
• W4221027466 cites W2074563683 @default.
• W4221027466 cites W2099838214 @default.
• W4221027466 cites W2103561970 @default.
• W4221027466 cites W2113760558 @default.
• W4221027466 cites W2116149022 @default.
• W4221027466 cites W2116810060 @default.
• W4221027466 cites W2136106925 @default.
• W4221027466 cites W2140317231 @default.
• W4221027466 cites W2145632027 @default.
• W4221027466 cites W2152189242 @default.
• W4221027466 cites W2162013229 @default.
• W4221027466 cites W2171844927 @default.
• W4221027466 cites W2201264930 @default.
• W4221027466 cites W2238633398 @default.
• W4221027466 cites W2277360215 @default.
• W4221027466 cites W2331840080 @default.
• W4221027466 cites W2542623336 @default.
• W4221027466 cites W2792492790 @default.
• W4221027466 cites W2811436780 @default.
• W4221027466 cites W2955593853 @default.
• W4221027466 cites W3215689618 @default.
• W4221027466 cites W4211170672 @default.
• W4221027466 cites W4296024375 @default.
• W4221027466 doi "https://doi.org/10.3389/fmed.2022.854300" @default.
• W4221027466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35433766" @default.
• W4221027466 hasPublicationYear "2022" @default.
• W4221027466 type Work @default.
• W4221027466 citedByCount "4" @default.
• W4221027466 countsByYear W42210274662022 @default.
• W4221027466 countsByYear W42210274662023 @default.
• W4221027466 crossrefType "journal-article" @default.
• W4221027466 hasAuthorship W4221027466A5011331009 @default.
• W4221027466 hasAuthorship W4221027466A5024792434 @default.
• W4221027466 hasAuthorship W4221027466A5036202917 @default.
• W4221027466 hasAuthorship W4221027466A5056053058 @default.
• W4221027466 hasAuthorship W4221027466A5057620126 @default.
• W4221027466 hasAuthorship W4221027466A5083753979 @default.
• W4221027466 hasBestOaLocation W42210274661 @default.
• W4221027466 hasConcept C126322002 @default.
• W4221027466 hasConcept C126894567 @default.
• W4221027466 hasConcept C159641895 @default.
• W4221027466 hasConcept C188816634 @default.
• W4221027466 hasConcept C201903717 @default.
• W4221027466 hasConcept C207103383 @default.
• W4221027466 hasConcept C2778653478 @default.
• W4221027466 hasConcept C2908647359 @default.
• W4221027466 hasConcept C44249647 @default.
• W4221027466 hasConcept C50382708 @default.
• W4221027466 hasConcept C54847362 @default.
• W4221027466 hasConcept C71924100 @default.
• W4221027466 hasConcept C99454951 @default.
• W4221027466 hasConceptScore W4221027466C126322002 @default.
• W4221027466 hasConceptScore W4221027466C126894567 @default.
• W4221027466 hasConceptScore W4221027466C159641895 @default.
• W4221027466 hasConceptScore W4221027466C188816634 @default.
• W4221027466 hasConceptScore W4221027466C201903717 @default.
• W4221027466 hasConceptScore W4221027466C207103383 @default.
• W4221027466 hasConceptScore W4221027466C2778653478 @default.
• W4221027466 hasConceptScore W4221027466C2908647359 @default.
• W4221027466 hasConceptScore W4221027466C44249647 @default.
• W4221027466 hasConceptScore W4221027466C50382708 @default.
• W4221027466 hasConceptScore W4221027466C54847362 @default.
• W4221027466 hasConceptScore W4221027466C71924100 @default.
• W4221027466 hasConceptScore W4221027466C99454951 @default.
• W4221027466 hasLocation W42210274661 @default.
• W4221027466 hasLocation W42210274662 @default.
• W4221027466 hasLocation W42210274663 @default.
• W4221027466 hasOpenAccess W4221027466 @default.
• W4221027466 hasPrimaryLocation W42210274661 @default.
• W4221027466 hasRelatedWork W1971368128 @default.
• W4221027466 hasRelatedWork W2097667855 @default.
• W4221027466 hasRelatedWork W23151206 @default.
• W4221027466 hasRelatedWork W2790532628 @default.
• W4221027466 hasRelatedWork W2994686985 @default.
• W4221027466 hasRelatedWork W3142512143 @default.
• W4221027466 hasRelatedWork W3205964248 @default.
• W4221027466 hasRelatedWork W4281722959 @default.
• W4221027466 hasRelatedWork W4320929188 @default.
• W4221027466 hasRelatedWork W4379796428 @default.

• next