FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221036887> ?p ?o ?g. }

• W4221036887 endingPage "825" @default.
• W4221036887 startingPage "818" @default.
• W4221036887 abstract "Objective Advances in imaging technologies have precipitated uncertainty and inconsistency in the management of neurologically intact patients presenting to the Emergency Department (ED) with non-traumatic sudden onset severe headache with a clinical suspicion of subarachnoid haemorrhage (SAH). The objective of this systematic review was to evaluate diagnostic strategies in these patients. Methods Studies assessing any decision rule or diagnostic test for evaluating neurologically intact adults with a severe headache, reaching maximum intensity within 1 hour, were eligible. Eighteen databases (including MEDLINE and Embase) were searched. Quality was assessed using QUADAS-2. Where appropriate, hierarchical bivariate meta-analysis was used to synthesise diagnostic accuracy results. Results Thirty-seven studies were included. Eight studies assessing the Ottawa SAH clinical decision rule were pooled; sensitivity 99.5% (95% CI 90.8 to 100), specificity 24% (95% CI 15.5 to 34.4). Four studies assessing CT within 6 hours of headache onset were pooled; sensitivity 98.7% (95% CI 96.5 to 100), specificity 100% (95% CI 99.7 to 100). The sensitivity of CT beyond 6 hours was considerably lower (≤90%; 2 studies). Three studies assessing lumbar puncture (LP; spectrophotometric analysis) following negative CT were pooled; sensitivity 100% (95% CI 100 to 100), specificity 95% (95% CI 86.0 to 98.5). Conclusion The Ottawa SAH Rule rules out further investigation in only a small proportion of patients. CT undertaken within 6 hours (with expertise of a neuroradiologist or radiologist who routinely interprets brain images) is highly accurate and likely to be sufficient to rule out SAH; CT beyond 6 hours is much less sensitive. The CT–LP pathway is highly sensitive for detecting SAH and some alternative diagnoses, although LP results in some false positive results." @default.
• W4221036887 created "2022-04-03" @default.
• W4221036887 creator A5008351749 @default.
• W4221036887 creator A5014786882 @default.
• W4221036887 creator A5014871379 @default.
• W4221036887 creator A5018836065 @default.
• W4221036887 creator A5042356904 @default.
• W4221036887 creator A5073128022 @default.
• W4221036887 creator A5077862180 @default.
• W4221036887 creator A5085275264 @default.
• W4221036887 creator A5087069990 @default.
• W4221036887 creator A5090867877 @default.
• W4221036887 date "2022-03-31" @default.
• W4221036887 modified "2023-09-26" @default.
• W4221036887 title "Management of patients presenting to the emergency department with sudden onset severe headache: systematic review of diagnostic accuracy studies" @default.
• W4221036887 cites W1510471886 @default.
• W4221036887 cites W1528652957 @default.
• W4221036887 cites W1602378024 @default.
• W4221036887 cites W1986498500 @default.
• W4221036887 cites W1987735862 @default.
• W4221036887 cites W1998942089 @default.
• W4221036887 cites W2003020304 @default.
• W4221036887 cites W2051094013 @default.
• W4221036887 cites W2055675320 @default.
• W4221036887 cites W2058041925 @default.
• W4221036887 cites W2059448755 @default.
• W4221036887 cites W2062855746 @default.
• W4221036887 cites W2077835927 @default.
• W4221036887 cites W2088721801 @default.
• W4221036887 cites W2107638293 @default.
• W4221036887 cites W2108736386 @default.
• W4221036887 cites W2114344165 @default.
• W4221036887 cites W2116241776 @default.
• W4221036887 cites W2124010614 @default.
• W4221036887 cites W2126727011 @default.
• W4221036887 cites W2142614828 @default.
• W4221036887 cites W2151659049 @default.
• W4221036887 cites W2151958335 @default.
• W4221036887 cites W2153848288 @default.
• W4221036887 cites W2155279177 @default.
• W4221036887 cites W2155587611 @default.
• W4221036887 cites W2155769144 @default.
• W4221036887 cites W2208910311 @default.
• W4221036887 cites W2283332943 @default.
• W4221036887 cites W2335324675 @default.
• W4221036887 cites W2426015378 @default.
• W4221036887 cites W2519404466 @default.
• W4221036887 cites W2522355087 @default.
• W4221036887 cites W2589972487 @default.
• W4221036887 cites W2770498237 @default.
• W4221036887 cites W2772153440 @default.
• W4221036887 cites W2775833086 @default.
• W4221036887 cites W2785704959 @default.
• W4221036887 cites W2809801284 @default.
• W4221036887 cites W2898997974 @default.
• W4221036887 cites W2899614816 @default.
• W4221036887 cites W2914494406 @default.
• W4221036887 cites W2992708768 @default.
• W4221036887 cites W3013681994 @default.
• W4221036887 cites W3121606801 @default.
• W4221036887 cites W4237230349 @default.
• W4221036887 doi "https://doi.org/10.1136/emermed-2021-211900" @default.
• W4221036887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35361627" @default.
• W4221036887 hasPublicationYear "2022" @default.
• W4221036887 type Work @default.
• W4221036887 citedByCount "1" @default.
• W4221036887 countsByYear W42210368872023 @default.
• W4221036887 crossrefType "journal-article" @default.
• W4221036887 hasAuthorship W4221036887A5008351749 @default.
• W4221036887 hasAuthorship W4221036887A5014786882 @default.
• W4221036887 hasAuthorship W4221036887A5014871379 @default.
• W4221036887 hasAuthorship W4221036887A5018836065 @default.
• W4221036887 hasAuthorship W4221036887A5042356904 @default.
• W4221036887 hasAuthorship W4221036887A5073128022 @default.
• W4221036887 hasAuthorship W4221036887A5077862180 @default.
• W4221036887 hasAuthorship W4221036887A5085275264 @default.
• W4221036887 hasAuthorship W4221036887A5087069990 @default.
• W4221036887 hasAuthorship W4221036887A5090867877 @default.
• W4221036887 hasBestOaLocation W42210368871 @default.
• W4221036887 hasConcept C118552586 @default.
• W4221036887 hasConcept C126322002 @default.
• W4221036887 hasConcept C126838900 @default.
• W4221036887 hasConcept C143409427 @default.
• W4221036887 hasConcept C17744445 @default.
• W4221036887 hasConcept C199539241 @default.
• W4221036887 hasConcept C2779473830 @default.
• W4221036887 hasConcept C2779651940 @default.
• W4221036887 hasConcept C2780066322 @default.
• W4221036887 hasConcept C2780724011 @default.
• W4221036887 hasConcept C2909330790 @default.
• W4221036887 hasConcept C3020132585 @default.
• W4221036887 hasConcept C71924100 @default.
• W4221036887 hasConcept C95190672 @default.
• W4221036887 hasConceptScore W4221036887C118552586 @default.
• W4221036887 hasConceptScore W4221036887C126322002 @default.
• W4221036887 hasConceptScore W4221036887C126838900 @default.
• W4221036887 hasConceptScore W4221036887C143409427 @default.
• W4221036887 hasConceptScore W4221036887C17744445 @default.

• next