Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221041115> ?p ?o ?g. }
- W4221041115 endingPage "388" @default.
- W4221041115 startingPage "388" @default.
- W4221041115 abstract "Carried in the nasal passages by up to 30% of humans, Staphylococcus aureus is recognized to be a successful opportunistic pathogen. It is a frequent cause of infections of the upper respiratory tract, including sinusitis, and of the skin, typically abscesses, as well as of food poisoning and medical device contamination. The antimicrobial resistance of such, often chronic, health conditions is underpinned by the unique structure of bacterial biofilm, which is the focus of increasing research to try to overcome this serious public health challenge. Due to the protective barrier of an exopolysaccharide matrix, bacteria that are embedded within biofilm are highly resistant both to an infected individual's immune response and to any treating antibiotics. An in-depth appraisal of the stepwise progression of biofilm formation by S. aureus, used as a model infection for all cases of bacterial antibiotic resistance, has enhanced understanding of this complicated microscopic structure and served to highlight possible intervention targets for both patient cure and community infection control. While antibiotic therapy offers a practical means of treatment and prevention, the most favorable results are achieved in combination with other methods. This review provides an overview of S. aureus biofilm development, outlines the current range of anti-biofilm agents that are used against each stage and summarizes their relative merits." @default.
- W4221041115 created "2022-04-03" @default.
- W4221041115 creator A5036897766 @default.
- W4221041115 creator A5056951761 @default.
- W4221041115 date "2022-03-23" @default.
- W4221041115 modified "2023-10-17" @default.
- W4221041115 title "Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention" @default.
- W4221041115 cites W1543474898 @default.
- W4221041115 cites W1550624813 @default.
- W4221041115 cites W1559607065 @default.
- W4221041115 cites W1570448267 @default.
- W4221041115 cites W1599420007 @default.
- W4221041115 cites W1604061599 @default.
- W4221041115 cites W1604874736 @default.
- W4221041115 cites W1852799255 @default.
- W4221041115 cites W1862098312 @default.
- W4221041115 cites W1878404532 @default.
- W4221041115 cites W1905861186 @default.
- W4221041115 cites W1907600034 @default.
- W4221041115 cites W1940390013 @default.
- W4221041115 cites W1945796226 @default.
- W4221041115 cites W1958721887 @default.
- W4221041115 cites W1964424377 @default.
- W4221041115 cites W1967239401 @default.
- W4221041115 cites W1968046235 @default.
- W4221041115 cites W1973622994 @default.
- W4221041115 cites W1973675012 @default.
- W4221041115 cites W1976704632 @default.
- W4221041115 cites W1976771829 @default.
- W4221041115 cites W1976780773 @default.
- W4221041115 cites W1977408323 @default.
- W4221041115 cites W1978037892 @default.
- W4221041115 cites W1979616917 @default.
- W4221041115 cites W1981369081 @default.
- W4221041115 cites W1982433425 @default.
- W4221041115 cites W1985905860 @default.
- W4221041115 cites W1987400078 @default.
- W4221041115 cites W1990589377 @default.
- W4221041115 cites W1995611257 @default.
- W4221041115 cites W1996064131 @default.
- W4221041115 cites W1996442931 @default.
- W4221041115 cites W1998677332 @default.
- W4221041115 cites W2000812746 @default.
- W4221041115 cites W2001760607 @default.
- W4221041115 cites W2003086561 @default.
- W4221041115 cites W2003208348 @default.
- W4221041115 cites W2005900494 @default.
- W4221041115 cites W2006333863 @default.
- W4221041115 cites W2011596188 @default.
- W4221041115 cites W2018989138 @default.
- W4221041115 cites W2019098068 @default.
- W4221041115 cites W2020556581 @default.
- W4221041115 cites W2020612301 @default.
- W4221041115 cites W2029738070 @default.
- W4221041115 cites W2030596058 @default.
- W4221041115 cites W2031965772 @default.
- W4221041115 cites W2035756601 @default.
- W4221041115 cites W2035815770 @default.
- W4221041115 cites W2036943908 @default.
- W4221041115 cites W2037492976 @default.
- W4221041115 cites W2038329167 @default.
- W4221041115 cites W2038907399 @default.
- W4221041115 cites W2043032580 @default.
- W4221041115 cites W2043263168 @default.
- W4221041115 cites W2043346930 @default.
- W4221041115 cites W2045842947 @default.
- W4221041115 cites W2048787993 @default.
- W4221041115 cites W2049876083 @default.
- W4221041115 cites W2053520315 @default.
- W4221041115 cites W2053524102 @default.
- W4221041115 cites W2055607275 @default.
- W4221041115 cites W2062128984 @default.
- W4221041115 cites W2065608233 @default.
- W4221041115 cites W2065737889 @default.
- W4221041115 cites W2066767199 @default.
- W4221041115 cites W2068294914 @default.
- W4221041115 cites W2070300719 @default.
- W4221041115 cites W2073550483 @default.
- W4221041115 cites W2075353447 @default.
- W4221041115 cites W2075359954 @default.
- W4221041115 cites W2080818083 @default.
- W4221041115 cites W2082111828 @default.
- W4221041115 cites W2082707689 @default.
- W4221041115 cites W2084387253 @default.
- W4221041115 cites W2084783722 @default.
- W4221041115 cites W2086165685 @default.
- W4221041115 cites W2086368575 @default.
- W4221041115 cites W2088137635 @default.
- W4221041115 cites W2090357739 @default.
- W4221041115 cites W2091442022 @default.
- W4221041115 cites W2091813393 @default.
- W4221041115 cites W2096274970 @default.
- W4221041115 cites W2097088367 @default.
- W4221041115 cites W2097480719 @default.
- W4221041115 cites W2098300761 @default.
- W4221041115 cites W2098393621 @default.
- W4221041115 cites W2098785211 @default.
- W4221041115 cites W2103455329 @default.