FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221062021> ?p ?o ?g. }

• W4221062021 abstract "Abstract Background Although some evidence suggests an association between obstructive sleep apnea (OSA) and gestational diabetes mellitus (GDM), its consequences still remain largely unknown. We sought to determine whether OSA is associated with higher inflammation and sympathetic levels in GDM, and to relate them with insulin resistance and perinatal outcomes. Methods OSA was identified by polysomnography and defined as an apnea–hypopnea index of ≥ 5 h −1 . Plasma cytokines (TNF-α, IL-1β, IL-6, IL-8, IL-10), metanephrine, and normetanephrine were determined by immunoassays. Results We included 17 patients with GDM and OSA and 34 without OSA. Women with GDM and OSA had higher normetanephrine concentrations [81 IQR (59–134) vs. 68 (51–81) pg/mL]. No differences in the inflammatory profile were found, while IL-1β was higher in patients with mean nocturnal oxyhemoglobin saturation ≤ 94%. We found positive correlations between increased sympathetic activation and IL-1β, with obstructive apneas, while time in REM showed an inverse relationship with IL-1β and metanephrine. Furthermore, IL-10 was inversely related with time in sleep stages 1–2, and with the arousal index, and it was positively related with time in slow-wave sleep. Significant correlations were also found between IL-1β and insulin resistance. There were no significant differences in neonatal characteristics; however, we found inverse relationships between IL-10 and birth weight (BW), and percentile of BW. Conclusions OSA increased sympathetic activity, and IL-1β concentration was higher in patients with GDM with lower nocturnal oxygenation, all of which were related with obstructive events, and time in REM. Moreover, IL-1β was related with insulin resistance, and IL-10 inversely correlated with neonatal BW." @default.
• W4221062021 created "2022-04-03" @default.
• W4221062021 creator A5001280033 @default.
• W4221062021 creator A5011363413 @default.
• W4221062021 creator A5021389281 @default.
• W4221062021 creator A5027687147 @default.
• W4221062021 creator A5029365566 @default.
• W4221062021 creator A5030313841 @default.
• W4221062021 creator A5031776060 @default.
• W4221062021 creator A5034366619 @default.
• W4221062021 creator A5037896151 @default.
• W4221062021 creator A5042977345 @default.
• W4221062021 creator A5044788607 @default.
• W4221062021 creator A5050878027 @default.
• W4221062021 creator A5057986718 @default.
• W4221062021 creator A5058066132 @default.
• W4221062021 creator A5065740663 @default.
• W4221062021 creator A5078491071 @default.
• W4221062021 creator A5082317714 @default.
• W4221062021 creator A5085228309 @default.
• W4221062021 creator A5085437112 @default.
• W4221062021 creator A5085785517 @default.
• W4221062021 creator A5087262327 @default.
• W4221062021 date "2022-03-18" @default.
• W4221062021 modified "2023-10-18" @default.
• W4221062021 title "Systemic inflammation and sympathetic activation in gestational diabetes mellitus with obstructive sleep apnea" @default.
• W4221062021 cites W1514813699 @default.
• W4221062021 cites W1545241942 @default.
• W4221062021 cites W1592674309 @default.
• W4221062021 cites W1603508213 @default.
• W4221062021 cites W1918196193 @default.
• W4221062021 cites W1993951911 @default.
• W4221062021 cites W2014810003 @default.
• W4221062021 cites W2015634373 @default.
• W4221062021 cites W2023651646 @default.
• W4221062021 cites W2041102049 @default.
• W4221062021 cites W2045433518 @default.
• W4221062021 cites W2081149633 @default.
• W4221062021 cites W2118968774 @default.
• W4221062021 cites W2119275218 @default.
• W4221062021 cites W2137926933 @default.
• W4221062021 cites W2139496586 @default.
• W4221062021 cites W2150723339 @default.
• W4221062021 cites W2163904778 @default.
• W4221062021 cites W2280346248 @default.
• W4221062021 cites W2306103306 @default.
• W4221062021 cites W2526707786 @default.
• W4221062021 cites W2560250901 @default.
• W4221062021 cites W2751731692 @default.
• W4221062021 cites W2765662534 @default.
• W4221062021 cites W2795097012 @default.
• W4221062021 cites W2884670748 @default.
• W4221062021 cites W2905565355 @default.
• W4221062021 cites W2948283619 @default.
• W4221062021 cites W2990058330 @default.
• W4221062021 cites W2992639448 @default.
• W4221062021 cites W3002356766 @default.
• W4221062021 cites W3006163254 @default.
• W4221062021 cites W3048623931 @default.
• W4221062021 cites W3136064813 @default.
• W4221062021 cites W3165228201 @default.
• W4221062021 cites W4211075899 @default.
• W4221062021 doi "https://doi.org/10.1186/s12890-022-01888-1" @default.
• W4221062021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35303833" @default.
• W4221062021 hasPublicationYear "2022" @default.
• W4221062021 type Work @default.
• W4221062021 citedByCount "4" @default.
• W4221062021 countsByYear W42210620212022 @default.
• W4221062021 countsByYear W42210620212023 @default.
• W4221062021 crossrefType "journal-article" @default.
• W4221062021 hasAuthorship W4221062021A5001280033 @default.
• W4221062021 hasAuthorship W4221062021A5011363413 @default.
• W4221062021 hasAuthorship W4221062021A5021389281 @default.
• W4221062021 hasAuthorship W4221062021A5027687147 @default.
• W4221062021 hasAuthorship W4221062021A5029365566 @default.
• W4221062021 hasAuthorship W4221062021A5030313841 @default.
• W4221062021 hasAuthorship W4221062021A5031776060 @default.
• W4221062021 hasAuthorship W4221062021A5034366619 @default.
• W4221062021 hasAuthorship W4221062021A5037896151 @default.
• W4221062021 hasAuthorship W4221062021A5042977345 @default.
• W4221062021 hasAuthorship W4221062021A5044788607 @default.
• W4221062021 hasAuthorship W4221062021A5050878027 @default.
• W4221062021 hasAuthorship W4221062021A5057986718 @default.
• W4221062021 hasAuthorship W4221062021A5058066132 @default.
• W4221062021 hasAuthorship W4221062021A5065740663 @default.
• W4221062021 hasAuthorship W4221062021A5078491071 @default.
• W4221062021 hasAuthorship W4221062021A5082317714 @default.
• W4221062021 hasAuthorship W4221062021A5085228309 @default.
• W4221062021 hasAuthorship W4221062021A5085437112 @default.
• W4221062021 hasAuthorship W4221062021A5085785517 @default.
• W4221062021 hasAuthorship W4221062021A5087262327 @default.
• W4221062021 hasBestOaLocation W42210620211 @default.
• W4221062021 hasConcept C126322002 @default.
• W4221062021 hasConcept C134018914 @default.
• W4221062021 hasConcept C2776006263 @default.
• W4221062021 hasConcept C2776252253 @default.
• W4221062021 hasConcept C2776377968 @default.
• W4221062021 hasConcept C2776914184 @default.
• W4221062021 hasConcept C2777391703 @default.
• W4221062021 hasConcept C2778205975 @default.

• next