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- W4221065103 abstract "Casimiroa edulis La Llave is known to contain unusual 5,6-dimethoxyflavones bearing a variously oxygenated B-ring. Phytochemical investigation of the leaves and the roots of C. edulis achieved the isolation of two new methoxylated flavones, named casedulones A (1) and B (2), together with 12 known analogues. Their unique structures were established with the aid of spectral analyses and total syntheses. Pre-treatment with 20 µM of 1 and 2 suppressed MMP-9 expression in LPS-mediated THP-1 cells, indicating that the characteristic flavonoids in C. edulis could be potential anti-angiogenics for cancer prevention." @default.
- W4221065103 created "2022-04-03" @default.
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- W4221065103 date "2022-03-04" @default.
- W4221065103 modified "2023-09-28" @default.
- W4221065103 title "Two new methoxylated flavones isolated from <i>Casimiroa edulis</i> La Llave and their MMP-9 inhibitory activity" @default.
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- W4221065103 doi "https://doi.org/10.1080/14786419.2022.2048300" @default.
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