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- W4221072013 abstract "Purpose: Reduction of activity of daily living by osteoarthritis of the knee (knee OA) is a major factor threatening healthy life expectancy. Thus, clarification of the pathophysiology of knee OA is desired. We reported that the clinical manifestations of knee OA have been shown to correlate with synovitis, but not with cartilage degeneration (Clin Rheumatol 2010;29:1185-1190). We also have shown that deficiency of perlecan expressed in synovium suppresses osteophyte formation in knee OA in mice, indicating that synovitis is involved in osteophyte formation (Matrix Biology 2013;32:178-187)." @default.
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- W4221072013 date "2022-04-01" @default.
- W4221072013 modified "2023-09-27" @default.
- W4221072013 title "OSTEOPHYTE FORMATION PROGRESSES WHEN SYNOVITIS WAS STRONGER IN MIDDLE-AGED POPULATIONS WITH GRADE 0 OF KELLGREN-LAWRENCE CLASSIFICATION -THE OSTEOARTHRITIS INITIATIVE" @default.
- W4221072013 doi "https://doi.org/10.1016/j.joca.2022.02.399" @default.
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