FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221085280> ?p ?o ?g. }

• W4221085280 abstract "Abstract Background Antidiabetic medications (ADM), especially sulfonylureas (SFU) and basal insulin (BI), are associated with increased risk of hypoglycemia, which is especially concerning among older adults in poor health. The objective of this study was to investigate prescribing patterns of ADM in older adults according to their health status. Methods This case control study analyzed administrative claims between 2013 and 2017 from a large national payer. The study population was derived from a nationwide database of 84,720 U.S. adults aged ≥65, who were enrolled in Medicare Advantage health insurance plans. Participants had type 2 diabetes on metformin monotherapy, and started a second-line ADM during the study period. The exposure was a binary variable for health status, with poor health defined by end-stage medical conditions, dementia, or residence in a long-term nursing facility. The outcome was a variable identifying which second-line ADM class was started, categorized as SFU, BI, or other (i.e. all other ADM classes combined). Results Over half of participants (54%) received SFU as initial second-line ADM, 14% received BI, and 32% received another ADM. In multivariable models, the odds of filling SFU or BI was higher for participants in poor health than those in good or intermediate health [OR 1.13 (95% CI 1.05-1.21) and OR 2.34 (95% CI 2.14-2.55), respectively]. SFU and BI were also more commonly filled by older adults with poor glycemic control. Conclusions Despite clinical consensus to use caution prescribing SFU and BI among older adults in poor health, these medications remain frequently used in this particularly vulnerable population." @default.
• W4221085280 created "2022-04-03" @default.
• W4221085280 creator A5004619468 @default.
• W4221085280 creator A5007288686 @default.
• W4221085280 creator A5014548361 @default.
• W4221085280 creator A5025331388 @default.
• W4221085280 creator A5026841591 @default.
• W4221085280 creator A5039295134 @default.
• W4221085280 creator A5042685051 @default.
• W4221085280 creator A5063037256 @default.
• W4221085280 creator A5071437513 @default.
• W4221085280 creator A5083007854 @default.
• W4221085280 date "2022-02-03" @default.
• W4221085280 modified "2023-10-18" @default.
• W4221085280 title "Initiating second-line antidiabetic medication among older adults with type 2 diabetes on Metformin" @default.
• W4221085280 cites W1529223681 @default.
• W4221085280 cites W1845444019 @default.
• W4221085280 cites W1849521086 @default.
• W4221085280 cites W1907243573 @default.
• W4221085280 cites W1985992465 @default.
• W4221085280 cites W2034471139 @default.
• W4221085280 cites W2046621583 @default.
• W4221085280 cites W2073776654 @default.
• W4221085280 cites W2093295645 @default.
• W4221085280 cites W2110840270 @default.
• W4221085280 cites W2135450314 @default.
• W4221085280 cites W2136432753 @default.
• W4221085280 cites W2199867537 @default.
• W4221085280 cites W2599076725 @default.
• W4221085280 cites W2611203237 @default.
• W4221085280 cites W2612213937 @default.
• W4221085280 cites W2751730132 @default.
• W4221085280 cites W2754097489 @default.
• W4221085280 cites W2754456969 @default.
• W4221085280 cites W2767197971 @default.
• W4221085280 cites W2767408736 @default.
• W4221085280 cites W2797967435 @default.
• W4221085280 cites W2802060224 @default.
• W4221085280 cites W2900316630 @default.
• W4221085280 cites W2913660676 @default.
• W4221085280 cites W2923829929 @default.
• W4221085280 cites W2965424236 @default.
• W4221085280 cites W2967214797 @default.
• W4221085280 cites W3007546177 @default.
• W4221085280 cites W3164837733 @default.
• W4221085280 cites W4294116629 @default.
• W4221085280 doi "https://doi.org/10.1186/s12877-022-02792-3" @default.
• W4221085280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35114955" @default.
• W4221085280 hasPublicationYear "2022" @default.
• W4221085280 type Work @default.
• W4221085280 citedByCount "4" @default.
• W4221085280 countsByYear W42210852802022 @default.
• W4221085280 countsByYear W42210852802023 @default.
• W4221085280 crossrefType "journal-article" @default.
• W4221085280 hasAuthorship W4221085280A5004619468 @default.
• W4221085280 hasAuthorship W4221085280A5007288686 @default.
• W4221085280 hasAuthorship W4221085280A5014548361 @default.
• W4221085280 hasAuthorship W4221085280A5025331388 @default.
• W4221085280 hasAuthorship W4221085280A5026841591 @default.
• W4221085280 hasAuthorship W4221085280A5039295134 @default.
• W4221085280 hasAuthorship W4221085280A5042685051 @default.
• W4221085280 hasAuthorship W4221085280A5063037256 @default.
• W4221085280 hasAuthorship W4221085280A5071437513 @default.
• W4221085280 hasAuthorship W4221085280A5083007854 @default.
• W4221085280 hasBestOaLocation W42210852801 @default.
• W4221085280 hasConcept C126322002 @default.
• W4221085280 hasConcept C134018914 @default.
• W4221085280 hasConcept C143095724 @default.
• W4221085280 hasConcept C151956035 @default.
• W4221085280 hasConcept C156957248 @default.
• W4221085280 hasConcept C2426938 @default.
• W4221085280 hasConcept C2777180221 @default.
• W4221085280 hasConcept C2779306644 @default.
• W4221085280 hasConcept C2780323712 @default.
• W4221085280 hasConcept C2780473172 @default.
• W4221085280 hasConcept C2780668416 @default.
• W4221085280 hasConcept C2908647359 @default.
• W4221085280 hasConcept C555293320 @default.
• W4221085280 hasConcept C71924100 @default.
• W4221085280 hasConcept C74909509 @default.
• W4221085280 hasConcept C98274493 @default.
• W4221085280 hasConcept C99454951 @default.
• W4221085280 hasConceptScore W4221085280C126322002 @default.
• W4221085280 hasConceptScore W4221085280C134018914 @default.
• W4221085280 hasConceptScore W4221085280C143095724 @default.
• W4221085280 hasConceptScore W4221085280C151956035 @default.
• W4221085280 hasConceptScore W4221085280C156957248 @default.
• W4221085280 hasConceptScore W4221085280C2426938 @default.
• W4221085280 hasConceptScore W4221085280C2777180221 @default.
• W4221085280 hasConceptScore W4221085280C2779306644 @default.
• W4221085280 hasConceptScore W4221085280C2780323712 @default.
• W4221085280 hasConceptScore W4221085280C2780473172 @default.
• W4221085280 hasConceptScore W4221085280C2780668416 @default.
• W4221085280 hasConceptScore W4221085280C2908647359 @default.
• W4221085280 hasConceptScore W4221085280C555293320 @default.
• W4221085280 hasConceptScore W4221085280C71924100 @default.
• W4221085280 hasConceptScore W4221085280C74909509 @default.
• W4221085280 hasConceptScore W4221085280C98274493 @default.
• W4221085280 hasConceptScore W4221085280C99454951 @default.
• W4221085280 hasIssue "1" @default.

• next