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• W4221088022 abstract "Cardiac rehabilitation (CR) following acute myocardial infarction (AMI) improves physical capacities and decreases hospitalizations and cardiovascular mortality. L-arginine is the substrate used by nitric oxide (NO) synthase to generate NO and it has been shown to exert its beneficial effects on endothelium driving vasodilatation, reducing inflammation, and ameliorating physical function. We hypothesized that L-arginine could enhance physical capacities in patients who underwent CR after AMI. We designed a study aimed to assess the effects of L-arginine administration on the physical capacity of patients who underwent coronary revascularization after AMI. The trial was carried out amid the COVID-19 pandemic. Patients were assigned, with a 2:1 ratio, to add to their standard therapy one bottle containing 1.66 g of L-arginine or one bottle of identical aspect apart from not containing L-arginine, twice a day orally for 3 weeks. Patients performed a 6-minute walking test (6MWT), and their Borg modified 0-10 rating of perceived exertion (BRPE) was assessed before starting and at the end of the treatment. Seventy-five patients receiving L-arginine, and 35 receiving placebo successfully completed the study. The 6MWT distance increased significantly in the L-arginine group compared with both baseline and placebo (P < 0.0001). Additionally, we observed a significant improvement in the BRPE in patients treated with L-arginine but not in the placebo group. Taken together, our data indicate that L-arginine potentiates the response to CR independently of age, sex, baseline functional capacity, and comorbid conditions. SIGNIFICANCE STATEMENT: This study shows for the first time that oral supplementation of L-arginine potentiates the response to cardiac rehabilitation after myocardial infarction and cardiac revascularization. Indeed, we observed a significant improvement in two fundamental parameters, namely, the 6-minute walking test and the Borg modified 0-10 rating of perceived exertion. Strikingly, the beneficial effects of L-arginine were independent of age, sex, comorbid conditions, and baseline functional capacity." @default.
• W4221088022 created "2022-04-03" @default.
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• W4221088022 date "2022-03-26" @default.
• W4221088022 modified "2023-10-12" @default.
• W4221088022 title "L-Arginine Enhances the Effects of Cardiac Rehabilitation on Physical Performance: New Insights for Managing Cardiovascular Patients During the COVID-19 Pandemic" @default.
• W4221088022 cites W1580052517 @default.
• W4221088022 cites W1580452814 @default.
• W4221088022 cites W1585653590 @default.
• W4221088022 cites W1966356997 @default.
• W4221088022 cites W1970580387 @default.
• W4221088022 cites W1972660743 @default.
• W4221088022 cites W1981594365 @default.
• W4221088022 cites W1988513614 @default.
• W4221088022 cites W1997407699 @default.
• W4221088022 cites W2004008756 @default.
• W4221088022 cites W2004145281 @default.
• W4221088022 cites W2014055624 @default.
• W4221088022 cites W2020699218 @default.
• W4221088022 cites W2025268843 @default.
• W4221088022 cites W2075333691 @default.
• W4221088022 cites W2086313546 @default.
• W4221088022 cites W2103815234 @default.
• W4221088022 cites W2109708615 @default.
• W4221088022 cites W2118652077 @default.
• W4221088022 cites W2122844888 @default.
• W4221088022 cites W2127527138 @default.
• W4221088022 cites W2131295867 @default.
• W4221088022 cites W2133040999 @default.
• W4221088022 cites W2140044661 @default.
• W4221088022 cites W2140157550 @default.
• W4221088022 cites W2165753570 @default.
• W4221088022 cites W2165901717 @default.
• W4221088022 cites W2290322993 @default.
• W4221088022 cites W2303236807 @default.
• W4221088022 cites W2402599050 @default.
• W4221088022 cites W2427094903 @default.
• W4221088022 cites W2464928704 @default.
• W4221088022 cites W2509729378 @default.
• W4221088022 cites W2560722665 @default.
• W4221088022 cites W2583663683 @default.
• W4221088022 cites W2739709612 @default.
• W4221088022 cites W2754054868 @default.
• W4221088022 cites W2798243705 @default.
• W4221088022 cites W2801490718 @default.
• W4221088022 cites W2883683957 @default.
• W4221088022 cites W2899848815 @default.
• W4221088022 cites W2905584148 @default.
• W4221088022 cites W2911726521 @default.
• W4221088022 cites W2937782282 @default.
• W4221088022 cites W2951345394 @default.
• W4221088022 cites W2980098657 @default.
• W4221088022 cites W2999373306 @default.
• W4221088022 cites W3016730950 @default.
• W4221088022 cites W3021842026 @default.
• W4221088022 cites W3031988160 @default.
• W4221088022 cites W3037173725 @default.
• W4221088022 cites W3042344365 @default.
• W4221088022 cites W3047529020 @default.
• W4221088022 cites W3109410822 @default.
• W4221088022 cites W3109650823 @default.
• W4221088022 cites W3117699317 @default.
• W4221088022 cites W3122398453 @default.
• W4221088022 cites W3139088610 @default.
• W4221088022 cites W3143399112 @default.
• W4221088022 cites W3166720317 @default.
• W4221088022 cites W3184966341 @default.
• W4221088022 cites W3190857150 @default.
• W4221088022 cites W3198065839 @default.
• W4221088022 cites W3199328058 @default.
• W4221088022 cites W3199627549 @default.
• W4221088022 cites W3200184376 @default.
• W4221088022 cites W3206868142 @default.
• W4221088022 cites W3209071110 @default.
• W4221088022 cites W3211020625 @default.
• W4221088022 cites W3211702775 @default.
• W4221088022 cites W3215337085 @default.
• W4221088022 cites W4200052023 @default.
• W4221088022 cites W4200161638 @default.
• W4221088022 cites W4200340499 @default.
• W4221088022 cites W4200446398 @default.
• W4221088022 cites W4200609415 @default.
• W4221088022 cites W4205317318 @default.
• W4221088022 cites W4205584341 @default.
• W4221088022 cites W4207066960 @default.
• W4221088022 cites W4213365713 @default.
• W4221088022 cites W4220804056 @default.

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