Matches in SemOpenAlex for { <https://semopenalex.org/work/W4221103923> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W4221103923 endingPage "36" @default.
- W4221103923 startingPage "28" @default.
- W4221103923 abstract "This study investigated the ameliorating potential of Annona muricata on Testosterone Propionate-Induced Benign prostatic hyperplasia (BPH) in male Wistar rats. Sixty (60) adult rats weighing 150 to 250g were grouped into six (6) of ten (10) rats. Group 1 (positive control) was fed with regular rat feeds and water. Group 2 (negative control), and Groups 3 - 6 were given regular feeds, water, and 3 mg/kg propionate for 28 days to induce benign prostatic hyperplasia. Group 3 to 6 were treated with 500, 1000, 1500, and 2000 mg/kg A. muricata extract respectively for 28 more days. Semen quality, Benign prostatic hyperplasia biomarkers, oxidative stress enzymes, Biomarkers of cardiac, renal, and hepatic function, Haematological indices as well as testis histology were investigated in treatment groups relative to controls. Results of Groups 3 to 6 show a significant (p<0.05) increase in sperm motility, viability, and count, with a significant decrease (p<0.05) in dead and abnormal sperm cells relative to the negative control. Prostate-specific antigen (PSA), a BPH indicator, showed a decrease and Carcinoembryonic antigen (CEA) an increase, however, both changes were non-significant (p>0.05). Cardiac biomarkers creatinine kinase MB (CKMB), D-dimer, and myoglobin, as well as liver, were not affected. The photomicrographs showing lesion in negative control were ameliorated by different concentrations of A. muricata extract and the tissues were restored to normal in treatment Groups 3 to 6. Annona muricata possesses ameliorative potentials on testosterone propionate-induced benign prostate hyperplasia. It has a positive effect on spermatogenesis and therefore, can boost semen quality." @default.
- W4221103923 created "2022-04-03" @default.
- W4221103923 creator A5006746766 @default.
- W4221103923 creator A5041785329 @default.
- W4221103923 creator A5066524881 @default.
- W4221103923 creator A5076447414 @default.
- W4221103923 date "2022-02-10" @default.
- W4221103923 modified "2023-09-26" @default.
- W4221103923 title "Ameliorating Potential of Annona muricata on Testosterone Propionate-Induced benign Prostatic Hyperplasia in Male Wistar Rats" @default.
- W4221103923 doi "https://doi.org/10.36348/sijb.2022.v05i02.001" @default.
- W4221103923 hasPublicationYear "2022" @default.
- W4221103923 type Work @default.
- W4221103923 citedByCount "1" @default.
- W4221103923 countsByYear W42211039232023 @default.
- W4221103923 crossrefType "journal-article" @default.
- W4221103923 hasAuthorship W4221103923A5006746766 @default.
- W4221103923 hasAuthorship W4221103923A5041785329 @default.
- W4221103923 hasAuthorship W4221103923A5066524881 @default.
- W4221103923 hasAuthorship W4221103923A5076447414 @default.
- W4221103923 hasBestOaLocation W42211039231 @default.
- W4221103923 hasConcept C121608353 @default.
- W4221103923 hasConcept C126322002 @default.
- W4221103923 hasConcept C134018914 @default.
- W4221103923 hasConcept C16685009 @default.
- W4221103923 hasConcept C2776235491 @default.
- W4221103923 hasConcept C2777562237 @default.
- W4221103923 hasConcept C2777911890 @default.
- W4221103923 hasConcept C2781087480 @default.
- W4221103923 hasConcept C2781115071 @default.
- W4221103923 hasConcept C71315377 @default.
- W4221103923 hasConcept C71924100 @default.
- W4221103923 hasConceptScore W4221103923C121608353 @default.
- W4221103923 hasConceptScore W4221103923C126322002 @default.
- W4221103923 hasConceptScore W4221103923C134018914 @default.
- W4221103923 hasConceptScore W4221103923C16685009 @default.
- W4221103923 hasConceptScore W4221103923C2776235491 @default.
- W4221103923 hasConceptScore W4221103923C2777562237 @default.
- W4221103923 hasConceptScore W4221103923C2777911890 @default.
- W4221103923 hasConceptScore W4221103923C2781087480 @default.
- W4221103923 hasConceptScore W4221103923C2781115071 @default.
- W4221103923 hasConceptScore W4221103923C71315377 @default.
- W4221103923 hasConceptScore W4221103923C71924100 @default.
- W4221103923 hasIssue "2" @default.
- W4221103923 hasLocation W42211039231 @default.
- W4221103923 hasOpenAccess W4221103923 @default.
- W4221103923 hasPrimaryLocation W42211039231 @default.
- W4221103923 hasRelatedWork W1977970588 @default.
- W4221103923 hasRelatedWork W2005311770 @default.
- W4221103923 hasRelatedWork W2013644072 @default.
- W4221103923 hasRelatedWork W2036602837 @default.
- W4221103923 hasRelatedWork W2070704005 @default.
- W4221103923 hasRelatedWork W2073069579 @default.
- W4221103923 hasRelatedWork W2142667461 @default.
- W4221103923 hasRelatedWork W2146554192 @default.
- W4221103923 hasRelatedWork W2152437371 @default.
- W4221103923 hasRelatedWork W2165434804 @default.
- W4221103923 hasVolume "5" @default.
- W4221103923 isParatext "false" @default.
- W4221103923 isRetracted "false" @default.
- W4221103923 workType "article" @default.