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• W4223417659 abstract "We use terahertz (THz) time-domain spectroscopy (TDS) to assess the crystalline state of indomethacin (IM) when loaded in smartFilms®. We found that smartFilms favour the amorphous IM (A-IM) for low loading concentrations. For higher concentrations, IM recrystallizes in its [Formula: see text]- crystalline form and the amount of A-IM in the smartFilms reduces. Both, [Formula: see text]- and A-IM are preferred over the more common [Formula: see text]- crystalline form, as they exhibit better water solubility, which can increase the oral bioavailability of the drug." @default.
• W4223417659 created "2022-04-14" @default.
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• W4223417659 date "2022-04-12" @default.
• W4223417659 modified "2023-09-26" @default.
• W4223417659 title "Non-destructive crystallinity assessment of indomethacin in tablets made from smartFilms® using terahertz time-domain spectroscopy" @default.
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• W4223417659 doi "https://doi.org/10.1038/s41598-022-10041-1" @default.
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