FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223482020> ?p ?o ?g. }

• W4223482020 endingPage "113864" @default.
• W4223482020 startingPage "113864" @default.
• W4223482020 abstract "Posttraumatic stress disorder (PTSD) is an anxiety disorder that occurs following exposure to somatic or psychotic trauma. Physical activity is known to improve symptoms of certain neuropsychiatric disorders. However, the role of exercise on acquired PTSD-like phenotype was not examined. The present study investigated the effects of prior moderate treadmill exercise on anxiety-like behaviors, serum corticosterone and BDNF levels, hippocampal BDNF and mRNA expression of apoptotic - related proteins in the single prolonged stress (SPS) as an animal model of PTSD in rats. Male and female rats underwent a regular treadmill exercise regimen (4 weeks, 5 days per week). Following the exercise, rats were exposed to SPS (restraint for 2 h, forced swimming for 20 min and ether anesthesia), and then they were kept undisturbed for 14 days. After testing anxiety-like behaviours in the elevated plus maze, the levels of corticosterone and BDNF in serum and BDNF and apoptosis markers (Bax, Bcl-2, and Caspase) in hippocampus were measured. Sedentary male and female SPS rats significantly (Ps ranging <0.05 to <0.0001) exhibited increased anxiety levels in the elevated plus maze, enhanced serum corticosterone, reduced serum and hippocampal BDNF and enhanced hippocampal apoptosis than the corresponding control group. Prior exercise significantly (Ps ranging <0.05 to <0.001) alleviated all SPS-induced behavioral and biochemical alterations as compared with the sedentary SPS rats. There were no significant differences in serum and hippocampal BDNF and serum corticosterone levels and hippocampal apoptotic markers between male and female rats in all of groups. Our findings strongly support that short term prior exercise training can prevent the harmful effects of traumatic events, and the resulting trauma-related disorders in both sexes." @default.
• W4223482020 created "2022-04-15" @default.
• W4223482020 creator A5011941536 @default.
• W4223482020 creator A5017074594 @default.
• W4223482020 creator A5056164561 @default.
• W4223482020 creator A5062089279 @default.
• W4223482020 creator A5071662680 @default.
• W4223482020 creator A5080640690 @default.
• W4223482020 date "2022-06-01" @default.
• W4223482020 modified "2023-09-25" @default.
• W4223482020 title "Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder" @default.
• W4223482020 cites W1964919587 @default.
• W4223482020 cites W1968566223 @default.
• W4223482020 cites W1968619648 @default.
• W4223482020 cites W1974167172 @default.
• W4223482020 cites W1988116691 @default.
• W4223482020 cites W1999871144 @default.
• W4223482020 cites W2001092446 @default.
• W4223482020 cites W2003280610 @default.
• W4223482020 cites W2006256785 @default.
• W4223482020 cites W2012403948 @default.
• W4223482020 cites W2012470325 @default.
• W4223482020 cites W2013990078 @default.
• W4223482020 cites W2022683726 @default.
• W4223482020 cites W2022789965 @default.
• W4223482020 cites W2026021912 @default.
• W4223482020 cites W2026298598 @default.
• W4223482020 cites W2027585389 @default.
• W4223482020 cites W2031156721 @default.
• W4223482020 cites W2032058764 @default.
• W4223482020 cites W2036886147 @default.
• W4223482020 cites W2039047753 @default.
• W4223482020 cites W2041923645 @default.
• W4223482020 cites W2047575176 @default.
• W4223482020 cites W2051996309 @default.
• W4223482020 cites W2058506163 @default.
• W4223482020 cites W2060986800 @default.
• W4223482020 cites W2073927880 @default.
• W4223482020 cites W2074450382 @default.
• W4223482020 cites W2076964952 @default.
• W4223482020 cites W2077084901 @default.
• W4223482020 cites W2078163068 @default.
• W4223482020 cites W2083047412 @default.
• W4223482020 cites W2109309568 @default.
• W4223482020 cites W2123640958 @default.
• W4223482020 cites W2145120190 @default.
• W4223482020 cites W2145152438 @default.
• W4223482020 cites W2150583919 @default.
• W4223482020 cites W2156196889 @default.
• W4223482020 cites W2160848559 @default.
• W4223482020 cites W2161840333 @default.
• W4223482020 cites W2166106170 @default.
• W4223482020 cites W2178723564 @default.
• W4223482020 cites W2185623954 @default.
• W4223482020 cites W2342439729 @default.
• W4223482020 cites W2409367239 @default.
• W4223482020 cites W2502966081 @default.
• W4223482020 cites W2545577063 @default.
• W4223482020 cites W2549761151 @default.
• W4223482020 cites W2581597337 @default.
• W4223482020 cites W2594371116 @default.
• W4223482020 cites W2604520534 @default.
• W4223482020 cites W2605930082 @default.
• W4223482020 cites W2734585321 @default.
• W4223482020 cites W2741520013 @default.
• W4223482020 cites W2753995969 @default.
• W4223482020 cites W2762311171 @default.
• W4223482020 cites W2765629808 @default.
• W4223482020 cites W2771886411 @default.
• W4223482020 cites W2790799698 @default.
• W4223482020 cites W2798596719 @default.
• W4223482020 cites W2799830923 @default.
• W4223482020 cites W2801963774 @default.
• W4223482020 cites W2811111728 @default.
• W4223482020 cites W2850067418 @default.
• W4223482020 cites W2895935284 @default.
• W4223482020 cites W2901536671 @default.
• W4223482020 cites W2907115646 @default.
• W4223482020 cites W2918724159 @default.
• W4223482020 cites W2925299885 @default.
• W4223482020 cites W2959420749 @default.
• W4223482020 cites W2963936193 @default.
• W4223482020 cites W2990652192 @default.
• W4223482020 cites W3000121801 @default.
• W4223482020 cites W3004609956 @default.
• W4223482020 cites W3009204937 @default.
• W4223482020 cites W3010740795 @default.
• W4223482020 cites W3012125399 @default.
• W4223482020 cites W3025356056 @default.
• W4223482020 cites W3034173219 @default.
• W4223482020 cites W3062350654 @default.
• W4223482020 cites W3208046584 @default.
• W4223482020 cites W4293247451 @default.
• W4223482020 cites W4312310089 @default.
• W4223482020 cites W2538464104 @default.
• W4223482020 doi "https://doi.org/10.1016/j.bbr.2022.113864" @default.
• W4223482020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35405172" @default.
• W4223482020 hasPublicationYear "2022" @default.

• next