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• W4223482153 abstract "Low levels of serum calcium, elevated levels of serum phosphorus and absent or abnormally low levels of serum parathyroid hormone characterize hypoparathyroidism, a rare endocrine deficiency illness. Hypoparathyroidism is caused by injury to the parathyroid gland as a result of surgery or autoimmune disease. In addition, hypoparathyroidism may develop due to genetic causes or infiltrative diseases. Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection is characterized by multi‑organ involvement, including the dysfunction of endocrine glands. Previous studies have demonstrated that SARS‑CoV‑2 infection induces endocrine tissue damage via various mechanisms, including direct cell damage from viral entry to the glands by binding to the angiotensin converting enzyme 2 receptors and replication, vasculitis, arterial and venous thrombosis, hypoxic cell damage, immune response and the cytokine storm. The effects of the new coronavirus, coronavirus disease 2019 (COVID‑19) on the parathyroid glands have received limited attention. Hypoparathyroidism has been observed in a small number of individuals as a result of SARS‑CoV‑2 infection. The present study describes the case of a patient with primary hypoparathyroidism induced by COVID‑19. Clinicians should also keep in mind that, despite the fact that SARS‑CoV‑2 has no known tropism for the parathyroid glands, it can result in primary hypoparathyroidism and decompensation of old primary hypoparathyroidism." @default.
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• W4223482153 date "2022-03-23" @default.
• W4223482153 modified "2023-10-14" @default.
• W4223482153 title "COVID‑19 induced hypoparathyroidism: A case report" @default.
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• W4223482153 doi "https://doi.org/10.3892/etm.2022.11276" @default.
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