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- W4223484189 abstract "Vascular occlusive events and hemorrhage in the brain affect thousands of lives across the globe every day. Thrombosis and hemostasis impact outcome after cerebrovascular disease, and its prevention and treatment include manipulation of systemic coagulation factors. The brain also has its own unique system for regulation of hemostasis.[1] Local thrombin generation in the brain affects the prognosis in epileptic seizures and multiple sclerosis,[2] while tissue plasminogen activator (tPa) affects blood–brain barrier permeability and is involved in Alzheimer's disease pathology.[3] This issue of Seminars of Thrombosis and Hemostasis will, in three parts, shed light on mechanisms and potential treatment targets in vascular occlusive events, in intracerebral and subarachnoid hemorrhage, and finally in the role of platelets and endogenous tPa in Alzheimer's and Parkinson's diseases." @default.
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- W4223484189 date "2022-04-01" @default.
- W4223484189 modified "2023-09-27" @default.
- W4223484189 title "Hemostasis and Neuroscience—Hemostasis and Fibrinolysis Involved in Brain Pathology and Brain Disorders" @default.
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- W4223484189 doi "https://doi.org/10.1055/s-0042-1742737" @default.
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