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- W4223484773 abstract "Angiogenesis is one of the hallmarks of cancer and plays a crucial role in carcinogenesis and progression of epithelial ovarian cancer. Antiangiogenic agent is the first approved targeted agent in ovarian cancer. Anti-angiogenic agents mainly include agents target VEGF/VEGFR pathway, such as bevacizumab and agents target receptor tyrosine kinase, and non-VEGF/VEGFR targets of angiogenesis. Antiangiogenic agents demonstrate certain effects in ovarian cancer treatment either as monotherapy or combined with chemotherapy. Unfortunately, antiangiogenic agents, such as bevacizumab, integrated into the ovarian cancer treatment paradigm do not increase cures. Thus, the benefits of anti-angiogenic agents must be carefully weighed against the cost and associated toxicities. Antiangiogenic agents drug resistance and short of predictive biomarkers are main obstacles in ovarian cancer treatment. A combination of poly (ADP-ribose) polymerase inhibitors or immune checkpoint inhibitors might be great strategies to overcome resistance as well as enhance anti-tumor activity of anti-angiogenic drugs. Predictive biomarkers of antiangiogenic agents are in urgent need." @default.
- W4223484773 created "2022-04-15" @default.
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- W4223484773 creator A5049709453 @default.
- W4223484773 date "2022-04-12" @default.
- W4223484773 modified "2023-09-26" @default.
- W4223484773 title "Antiangiogenic Strategies in Epithelial Ovarian Cancer: Mechanism, Resistance, and Combination Therapy" @default.
- W4223484773 cites W1781764024 @default.
- W4223484773 cites W1793338775 @default.
- W4223484773 cites W1866961778 @default.
- W4223484773 cites W1968209756 @default.
- W4223484773 cites W1972099322 @default.
- W4223484773 cites W1973268287 @default.
- W4223484773 cites W1976448012 @default.
- W4223484773 cites W1983150990 @default.
- W4223484773 cites W1985604577 @default.
- W4223484773 cites W1993944960 @default.
- W4223484773 cites W1997761243 @default.
- W4223484773 cites W2002419036 @default.
- W4223484773 cites W2009007206 @default.
- W4223484773 cites W2011264584 @default.
- W4223484773 cites W2012063336 @default.
- W4223484773 cites W2014935555 @default.
- W4223484773 cites W2017176305 @default.
- W4223484773 cites W2017414151 @default.
- W4223484773 cites W2018889021 @default.
- W4223484773 cites W2026256230 @default.
- W4223484773 cites W2034158072 @default.
- W4223484773 cites W2039195665 @default.
- W4223484773 cites W2044835625 @default.
- W4223484773 cites W2060982698 @default.
- W4223484773 cites W2076415360 @default.
- W4223484773 cites W2091206206 @default.
- W4223484773 cites W2098757775 @default.
- W4223484773 cites W2101653483 @default.
- W4223484773 cites W2102195694 @default.
- W4223484773 cites W2104607769 @default.
- W4223484773 cites W2109400578 @default.
- W4223484773 cites W2111658171 @default.
- W4223484773 cites W2113122060 @default.
- W4223484773 cites W2113467627 @default.
- W4223484773 cites W2116183806 @default.
- W4223484773 cites W2117692326 @default.
- W4223484773 cites W2123363005 @default.
- W4223484773 cites W2125853921 @default.
- W4223484773 cites W2128178813 @default.
- W4223484773 cites W2132193955 @default.
- W4223484773 cites W2133537644 @default.
- W4223484773 cites W2135525536 @default.
- W4223484773 cites W2135947389 @default.
- W4223484773 cites W2136689090 @default.
- W4223484773 cites W2147622445 @default.
- W4223484773 cites W2150654881 @default.
- W4223484773 cites W2150683293 @default.
- W4223484773 cites W2151509048 @default.
- W4223484773 cites W2153262774 @default.
- W4223484773 cites W2154056804 @default.
- W4223484773 cites W2156268500 @default.
- W4223484773 cites W2162645859 @default.
- W4223484773 cites W2170928115 @default.
- W4223484773 cites W2171658624 @default.
- W4223484773 cites W2173026051 @default.
- W4223484773 cites W2199159118 @default.
- W4223484773 cites W2200887263 @default.
- W4223484773 cites W2289502345 @default.
- W4223484773 cites W2293618284 @default.
- W4223484773 cites W2311097689 @default.
- W4223484773 cites W2318409487 @default.
- W4223484773 cites W2324967303 @default.
- W4223484773 cites W2340636398 @default.
- W4223484773 cites W2344322811 @default.
- W4223484773 cites W2403815535 @default.
- W4223484773 cites W2412434883 @default.
- W4223484773 cites W2518249527 @default.
- W4223484773 cites W2528228811 @default.
- W4223484773 cites W2541714644 @default.
- W4223484773 cites W2558389544 @default.
- W4223484773 cites W2578528809 @default.
- W4223484773 cites W2587481375 @default.
- W4223484773 cites W2593027991 @default.
- W4223484773 cites W2605456582 @default.
- W4223484773 cites W2620065392 @default.
- W4223484773 cites W2725398806 @default.
- W4223484773 cites W2728169914 @default.
- W4223484773 cites W2737389832 @default.
- W4223484773 cites W2760162359 @default.
- W4223484773 cites W2769616494 @default.
- W4223484773 cites W2791328450 @default.
- W4223484773 cites W2807649309 @default.
- W4223484773 cites W2809966743 @default.
- W4223484773 cites W2810464703 @default.
- W4223484773 cites W2885351886 @default.
- W4223484773 cites W2889646458 @default.
- W4223484773 cites W2897430921 @default.
- W4223484773 cites W2901570052 @default.
- W4223484773 cites W2903353464 @default.