Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223491908> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4223491908 abstract "Abstract Background Radiation-induced nephropathy (RIN) is an impairment of function caused by ionizing radiation which develops after6-12 months as acute or after years as chronic period. Methods This paper aims to clarify, whether L-carnitine has a protective effect in the prevention of RIN in an infant rat model. Results Two-week-old forty male Wistar albino rats were divided into four groups such as control (C), L-carnitine alone (LC), irradiation alone (RT), and L-Carnitine before irradiation (L-carnitine + RT), injected with LC (300 mg/kg) i.p., 30 minutes before the irradiation. The rats in the RT and L-Carnitine + RT groups were irradiated individually with a single dose of 8 Gy. All animals underwent both Tc99m DTPA dynamic renal imaging and Tc99m DMSA static renal imaging at the end of three months follow-up period. Proximal tubular degeneration, tubular atrophy, interstitial fibrosis, and glomerular degeneration were assessed histopathologically. While the kidney damage caused by irradiation was shown in line with both scintigraphy and histopathology findings, it was shown that L-carnitine did not have any negative effects on the kidney. Also, we could not demonstrate the protective effect of L-carnitine on radiation-induced kidney damage, both scintigraphically and histopathologically. Conclusion Although kidney damage due to irradiation was created in infantile rats successfully, the protective effect of L-carnitine could not be demonstrated in our study." @default.
- W4223491908 created "2022-04-15" @default.
- W4223491908 creator A5000011739 @default.
- W4223491908 creator A5001844684 @default.
- W4223491908 creator A5009753212 @default.
- W4223491908 creator A5027248113 @default.
- W4223491908 creator A5036745583 @default.
- W4223491908 creator A5061170390 @default.
- W4223491908 creator A5074928131 @default.
- W4223491908 creator A5083581419 @default.
- W4223491908 creator A5085705572 @default.
- W4223491908 creator A5087090074 @default.
- W4223491908 date "2022-04-11" @default.
- W4223491908 modified "2023-10-16" @default.
- W4223491908 title "Does L-carnitine have a protectiveeffect on the development of radiationinducedkidney damage in infancy?Scintigraphic and histopathologicevaluation" @default.
- W4223491908 doi "https://doi.org/10.21203/rs.3.rs-1531095/v1" @default.
- W4223491908 hasPublicationYear "2022" @default.
- W4223491908 type Work @default.
- W4223491908 citedByCount "0" @default.
- W4223491908 crossrefType "posted-content" @default.
- W4223491908 hasAuthorship W4223491908A5000011739 @default.
- W4223491908 hasAuthorship W4223491908A5001844684 @default.
- W4223491908 hasAuthorship W4223491908A5009753212 @default.
- W4223491908 hasAuthorship W4223491908A5027248113 @default.
- W4223491908 hasAuthorship W4223491908A5036745583 @default.
- W4223491908 hasAuthorship W4223491908A5061170390 @default.
- W4223491908 hasAuthorship W4223491908A5074928131 @default.
- W4223491908 hasAuthorship W4223491908A5083581419 @default.
- W4223491908 hasAuthorship W4223491908A5085705572 @default.
- W4223491908 hasAuthorship W4223491908A5087090074 @default.
- W4223491908 hasBestOaLocation W42234919081 @default.
- W4223491908 hasConcept C111337013 @default.
- W4223491908 hasConcept C121332964 @default.
- W4223491908 hasConcept C126322002 @default.
- W4223491908 hasConcept C126894567 @default.
- W4223491908 hasConcept C134018914 @default.
- W4223491908 hasConcept C142724271 @default.
- W4223491908 hasConcept C185544564 @default.
- W4223491908 hasConcept C2778435403 @default.
- W4223491908 hasConcept C2779354088 @default.
- W4223491908 hasConcept C2779902710 @default.
- W4223491908 hasConcept C2780091579 @default.
- W4223491908 hasConcept C2781172350 @default.
- W4223491908 hasConcept C2989005 @default.
- W4223491908 hasConcept C544855455 @default.
- W4223491908 hasConcept C71924100 @default.
- W4223491908 hasConceptScore W4223491908C111337013 @default.
- W4223491908 hasConceptScore W4223491908C121332964 @default.
- W4223491908 hasConceptScore W4223491908C126322002 @default.
- W4223491908 hasConceptScore W4223491908C126894567 @default.
- W4223491908 hasConceptScore W4223491908C134018914 @default.
- W4223491908 hasConceptScore W4223491908C142724271 @default.
- W4223491908 hasConceptScore W4223491908C185544564 @default.
- W4223491908 hasConceptScore W4223491908C2778435403 @default.
- W4223491908 hasConceptScore W4223491908C2779354088 @default.
- W4223491908 hasConceptScore W4223491908C2779902710 @default.
- W4223491908 hasConceptScore W4223491908C2780091579 @default.
- W4223491908 hasConceptScore W4223491908C2781172350 @default.
- W4223491908 hasConceptScore W4223491908C2989005 @default.
- W4223491908 hasConceptScore W4223491908C544855455 @default.
- W4223491908 hasConceptScore W4223491908C71924100 @default.
- W4223491908 hasLocation W42234919081 @default.
- W4223491908 hasOpenAccess W4223491908 @default.
- W4223491908 hasPrimaryLocation W42234919081 @default.
- W4223491908 hasRelatedWork W1975536848 @default.
- W4223491908 hasRelatedWork W2020959757 @default.
- W4223491908 hasRelatedWork W2042033030 @default.
- W4223491908 hasRelatedWork W2044943066 @default.
- W4223491908 hasRelatedWork W2082456910 @default.
- W4223491908 hasRelatedWork W2127085070 @default.
- W4223491908 hasRelatedWork W2146211406 @default.
- W4223491908 hasRelatedWork W2163591087 @default.
- W4223491908 hasRelatedWork W2400445066 @default.
- W4223491908 hasRelatedWork W76394038 @default.
- W4223491908 isParatext "false" @default.
- W4223491908 isRetracted "false" @default.
- W4223491908 workType "article" @default.