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- W4223497166 abstract "Tick-borne encephalitis virus’ (TBEV) geographic range and the human incidence are increasing throughout Europe, putting a number of non-endemic regions and countries at risk of outbreaks. In spring 2020, there was an outbreak of tick-born encephalitis (TBE) in Ain, Eastern France, where the virus had never been detected before. All patients but one had consumed traditional unpasteurised raw goat cheese from a local producer. We conducted an investigation in the suspected farm using an integrative One Health approach. Our methodology included (i) the detection of virus in cheese and milk products, (ii) serological testing of all animals in the suspected farm and surrounding farms, (iii) an analysis of the landscape and localisation of wooded area, (iv) the capture of questing ticks and small mammals for virus detection and estimating enzootic hazard, and (v) virus isolation and genome sequencing. This approach allowed us to confirm the alimentary origin of the TBE outbreak and witness in real-time the seroconversion of recently exposed individuals and excretion of virus in goat milk. In addition, we identified a wooded focus area where and around which there is a risk of TBEV exposure. We provide the first TBEV isolate responsible for the first alimentary-transmitted TBE in France, obtained its full-length genome sequence, and found that it belongs to the European subtype of TBEV. TBEV is now a notifiable human disease in France, which should facilitate surveillance of its incidence and distribution throughout France." @default.
- W4223497166 created "2022-04-15" @default.
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- W4223497166 date "2022-04-11" @default.
- W4223497166 modified "2023-09-30" @default.
- W4223497166 title "A One-Health Approach to Investigating an Outbreak of Alimentary Tick-Borne Encephalitis in a Non-endemic Area in France (Ain, Eastern France): A Longitudinal Serological Study in Livestock, Detection in Ticks, and the First Tick-Borne Encephalitis Virus Isolation and Molecular Characterisation" @default.
- W4223497166 cites W10605091 @default.
- W4223497166 cites W1520302982 @default.
- W4223497166 cites W17143672 @default.
- W4223497166 cites W1976168424 @default.
- W4223497166 cites W1984390661 @default.
- W4223497166 cites W1992096074 @default.
- W4223497166 cites W1998494157 @default.
- W4223497166 cites W2007510392 @default.
- W4223497166 cites W2013482224 @default.
- W4223497166 cites W2014001082 @default.
- W4223497166 cites W2027071413 @default.
- W4223497166 cites W2029107729 @default.
- W4223497166 cites W2029653373 @default.
- W4223497166 cites W2030735517 @default.
- W4223497166 cites W2041631951 @default.
- W4223497166 cites W2045264817 @default.
- W4223497166 cites W2047715558 @default.
- W4223497166 cites W2056110457 @default.
- W4223497166 cites W2069488864 @default.
- W4223497166 cites W2076636448 @default.
- W4223497166 cites W2099931035 @default.
- W4223497166 cites W2103441770 @default.
- W4223497166 cites W2112044806 @default.
- W4223497166 cites W2128521636 @default.
- W4223497166 cites W2129351827 @default.
- W4223497166 cites W2134729986 @default.
- W4223497166 cites W2140025627 @default.
- W4223497166 cites W2156364234 @default.
- W4223497166 cites W2168163625 @default.
- W4223497166 cites W2168662319 @default.
- W4223497166 cites W2194735419 @default.
- W4223497166 cites W2265015072 @default.
- W4223497166 cites W2336154607 @default.
- W4223497166 cites W235858054 @default.
- W4223497166 cites W235861049 @default.
- W4223497166 cites W2419102206 @default.
- W4223497166 cites W2474282822 @default.
- W4223497166 cites W2509694488 @default.
- W4223497166 cites W2607148452 @default.
- W4223497166 cites W2610994034 @default.
- W4223497166 cites W2616925143 @default.
- W4223497166 cites W2734757580 @default.
- W4223497166 cites W2759511478 @default.
- W4223497166 cites W2789843538 @default.
- W4223497166 cites W2798022761 @default.
- W4223497166 cites W2808186275 @default.
- W4223497166 cites W2884424964 @default.
- W4223497166 cites W2891706746 @default.
- W4223497166 cites W2896247479 @default.
- W4223497166 cites W2900603726 @default.
- W4223497166 cites W2907288783 @default.
- W4223497166 cites W2911619552 @default.
- W4223497166 cites W2920176758 @default.
- W4223497166 cites W2929048798 @default.
- W4223497166 cites W2938574745 @default.
- W4223497166 cites W2940196355 @default.
- W4223497166 cites W2946384917 @default.
- W4223497166 cites W2964141710 @default.
- W4223497166 cites W2971764439 @default.
- W4223497166 cites W2976594286 @default.
- W4223497166 cites W2982371951 @default.
- W4223497166 cites W2984710112 @default.
- W4223497166 cites W2994968453 @default.
- W4223497166 cites W3007081638 @default.
- W4223497166 cites W3007326406 @default.
- W4223497166 cites W3015981079 @default.
- W4223497166 cites W3023128901 @default.