Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223521912> ?p ?o ?g. }
- W4223521912 abstract "Spermatogenesis is an intricate developmental process during which undifferentiated spermatogonia, containing spermatogonial stem cells (SSCs), undergo self-renewal and differentiation to generate eventually mature spermatozoa. Spermatogenesis occurs in seminiferous tubules within the testis, and the seminiferous tubules harbor Sertoli and germ cells. Sertoli cells are an essential somatic cell type within the microenvironment that support and steer male germ cell development, whereas spermatogonia are the primitive male germ cells at the onset of spermatogenesis. While the developmental progression of Sertoli cells and spermatogonia has been well established in mice, much less is known in other mammalian species including pigs.To acquire knowledge of Sertoli cell and spermatogonial development in pigs, here we collected as many as nine ages of Duroc porcine testes from the neonate to sexual maturity, i.e., testes from 7-, 30-, 50-, 70-, 90-, 110-, 130-, 150- and 210-day-old boars, and performed histological and immunohistochemical analyses on testis sections. We first examined the development of spermatogenic cells and seminiferous tubules in porcine testes. Then, by immunofluorescence staining for marker proteins (AMH, SOX9, DBA, UCHL1, VASA, KIT, Ki67 and/or PCNA), we delved into the proliferative activity and development of Sertoli cells and of spermatogonial subtypes (pro-, undifferentiated and differentiating spermatogonia). Besides, by immunostaining for β-catenin and ZO-1, we studied the establishment of the blood-testis barrier in porcine testes.In this longitudinal study, we have systematically investigated the elaborate Sertoli cell and spermatogonial developmental patterns in pigs from the neonate to sexual maturity that have so far remained largely unknown. The findings not only extend the knowledge about spermatogenesis and testicular development in pigs, but also lay the theoretical groundwork for porcine breeding and rearing." @default.
- W4223521912 created "2022-04-15" @default.
- W4223521912 creator A5010675918 @default.
- W4223521912 creator A5016924930 @default.
- W4223521912 creator A5020606182 @default.
- W4223521912 creator A5023135578 @default.
- W4223521912 creator A5033818990 @default.
- W4223521912 creator A5059918486 @default.
- W4223521912 creator A5062825549 @default.
- W4223521912 creator A5067110746 @default.
- W4223521912 creator A5075899436 @default.
- W4223521912 date "2022-04-11" @default.
- W4223521912 modified "2023-10-10" @default.
- W4223521912 title "Sertoli cell and spermatogonial development in pigs" @default.
- W4223521912 cites W1864184149 @default.
- W4223521912 cites W1968074438 @default.
- W4223521912 cites W1970448922 @default.
- W4223521912 cites W1970611407 @default.
- W4223521912 cites W1971711433 @default.
- W4223521912 cites W1975619619 @default.
- W4223521912 cites W1978249879 @default.
- W4223521912 cites W1987159707 @default.
- W4223521912 cites W1993885215 @default.
- W4223521912 cites W1999865455 @default.
- W4223521912 cites W2001241935 @default.
- W4223521912 cites W2011560862 @default.
- W4223521912 cites W2020234109 @default.
- W4223521912 cites W2029507508 @default.
- W4223521912 cites W2036788483 @default.
- W4223521912 cites W2056770467 @default.
- W4223521912 cites W2061759168 @default.
- W4223521912 cites W2064739153 @default.
- W4223521912 cites W2065241939 @default.
- W4223521912 cites W2069290653 @default.
- W4223521912 cites W2071934356 @default.
- W4223521912 cites W2074212982 @default.
- W4223521912 cites W2083248417 @default.
- W4223521912 cites W2097152977 @default.
- W4223521912 cites W2101319977 @default.
- W4223521912 cites W2112080359 @default.
- W4223521912 cites W2124282550 @default.
- W4223521912 cites W2126277966 @default.
- W4223521912 cites W2126486896 @default.
- W4223521912 cites W2136230328 @default.
- W4223521912 cites W2138910028 @default.
- W4223521912 cites W2142658169 @default.
- W4223521912 cites W2144131351 @default.
- W4223521912 cites W2146399757 @default.
- W4223521912 cites W2150030648 @default.
- W4223521912 cites W2167857115 @default.
- W4223521912 cites W2247695881 @default.
- W4223521912 cites W2286124328 @default.
- W4223521912 cites W2323157881 @default.
- W4223521912 cites W2408958865 @default.
- W4223521912 cites W2750969909 @default.
- W4223521912 cites W2763612459 @default.
- W4223521912 cites W2766117922 @default.
- W4223521912 cites W2793928888 @default.
- W4223521912 cites W2794680309 @default.
- W4223521912 cites W2800761804 @default.
- W4223521912 cites W2915193592 @default.
- W4223521912 cites W2920987358 @default.
- W4223521912 cites W2921786012 @default.
- W4223521912 cites W2982826615 @default.
- W4223521912 cites W2989934954 @default.
- W4223521912 cites W3000244730 @default.
- W4223521912 cites W3004046412 @default.
- W4223521912 cites W3023162312 @default.
- W4223521912 cites W3028375401 @default.
- W4223521912 cites W3143714690 @default.
- W4223521912 cites W3161662180 @default.
- W4223521912 cites W3176705332 @default.
- W4223521912 cites W2587143208 @default.
- W4223521912 doi "https://doi.org/10.1186/s40104-022-00687-2" @default.
- W4223521912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35399096" @default.
- W4223521912 hasPublicationYear "2022" @default.
- W4223521912 type Work @default.
- W4223521912 citedByCount "12" @default.
- W4223521912 countsByYear W42235219122022 @default.
- W4223521912 countsByYear W42235219122023 @default.
- W4223521912 crossrefType "journal-article" @default.
- W4223521912 hasAuthorship W4223521912A5010675918 @default.
- W4223521912 hasAuthorship W4223521912A5016924930 @default.
- W4223521912 hasAuthorship W4223521912A5020606182 @default.
- W4223521912 hasAuthorship W4223521912A5023135578 @default.
- W4223521912 hasAuthorship W4223521912A5033818990 @default.
- W4223521912 hasAuthorship W4223521912A5059918486 @default.
- W4223521912 hasAuthorship W4223521912A5062825549 @default.
- W4223521912 hasAuthorship W4223521912A5067110746 @default.
- W4223521912 hasAuthorship W4223521912A5075899436 @default.
- W4223521912 hasBestOaLocation W42235219121 @default.
- W4223521912 hasConcept C104317684 @default.
- W4223521912 hasConcept C123765429 @default.
- W4223521912 hasConcept C126322002 @default.
- W4223521912 hasConcept C134018914 @default.
- W4223521912 hasConcept C134305767 @default.
- W4223521912 hasConcept C16685009 @default.
- W4223521912 hasConcept C192536144 @default.
- W4223521912 hasConcept C203014093 @default.
- W4223521912 hasConcept C204232928 @default.