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• W4223543204 startingPage "759" @default.
• W4223543204 abstract "Plasmodium vivax malaria causes significant disease burden worldwide, especially in Latin America, Southeast Asia, and Oceania. P. vivax is characterized by the production of liver hypnozoites that cause clinical relapses upon periodic activation. Primaquine, an 8-aminoquinoline drug, has been the standard of care for decades to treat liver-stage P. vivax malaria; however, it requires long treatment regimens (one to two weeks) that lead to poor adherence and thus clinical relapses. Tafenoquine (TFQ), a newly available and efficacious single-dose 8-aminoquinoline, aims to address this challenge. Safe administration is possible when paired with the use of glucose-6-phosphate dehydrogenase (G6PD) diagnostics to prevent 8-aminoquinoline-induced hemolysis in patients with underlying G6PD deficiency (G6PDd).In this review, the authors present the recent literature regarding the pharmacology, efficacy, safety, and tolerability of TFQ and highlight regional differences in these areas. The authors also discuss the potential for TFQ, complemented with primaquine PQ and effective screening for G6PDd, to improve P. vivax clinical management and facilitate targeted mass drug administration in communities to decrease transmission.Clinical studies show therapeutic efficacy of TFQ as well as a good performance in terms of safety and tolerability. Additional research regarding the effectiveness and safety TFQ in malaria elimination strategies, such as targeted or mass drug administration, are needed." @default.
• W4223543204 created "2022-04-15" @default.
• W4223543204 creator A5014261294 @default.
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• W4223543204 creator A5078345762 @default.
• W4223543204 creator A5080802234 @default.
• W4223543204 creator A5088599431 @default.
• W4223543204 date "2022-04-13" @default.
• W4223543204 modified "2023-10-04" @default.
• W4223543204 title "Tafenoquine for the treatment of <i>Plasmodium vivax</i> malaria" @default.
• W4223543204 cites W1519586906 @default.
• W4223543204 cites W1551766403 @default.
• W4223543204 cites W1572475141 @default.
• W4223543204 cites W1623229978 @default.
• W4223543204 cites W1926568043 @default.
• W4223543204 cites W1966459680 @default.
• W4223543204 cites W196795570 @default.
• W4223543204 cites W1970778145 @default.
• W4223543204 cites W2010245350 @default.
• W4223543204 cites W2010940726 @default.
• W4223543204 cites W2023031926 @default.
• W4223543204 cites W2028585506 @default.
• W4223543204 cites W2082525341 @default.
• W4223543204 cites W2103205254 @default.
• W4223543204 cites W2104058573 @default.
• W4223543204 cites W2107071499 @default.
• W4223543204 cites W2113635277 @default.
• W4223543204 cites W2113932936 @default.
• W4223543204 cites W2117767554 @default.
• W4223543204 cites W2119444121 @default.
• W4223543204 cites W2120772405 @default.
• W4223543204 cites W2122753628 @default.
• W4223543204 cites W2123001877 @default.
• W4223543204 cites W2124740902 @default.
• W4223543204 cites W2125089473 @default.
• W4223543204 cites W2130272097 @default.
• W4223543204 cites W2132909764 @default.
• W4223543204 cites W2134845482 @default.
• W4223543204 cites W2145280379 @default.
• W4223543204 cites W2146952198 @default.
• W4223543204 cites W2154316070 @default.
• W4223543204 cites W2157838912 @default.
• W4223543204 cites W2159276995 @default.
• W4223543204 cites W2160959000 @default.
• W4223543204 cites W2161252729 @default.
• W4223543204 cites W2161535656 @default.
• W4223543204 cites W2165325867 @default.
• W4223543204 cites W2165686006 @default.
• W4223543204 cites W2169585492 @default.
• W4223543204 cites W2170788161 @default.
• W4223543204 cites W2178707295 @default.
• W4223543204 cites W2188194909 @default.
• W4223543204 cites W2312580379 @default.
• W4223543204 cites W2505536769 @default.
• W4223543204 cites W2507296118 @default.
• W4223543204 cites W2528317666 @default.
• W4223543204 cites W2556599517 @default.
• W4223543204 cites W2739361295 @default.
• W4223543204 cites W2749887661 @default.
• W4223543204 cites W2767584895 @default.
• W4223543204 cites W2789933043 @default.
• W4223543204 cites W2794349929 @default.
• W4223543204 cites W2799783118 @default.
• W4223543204 cites W2805525768 @default.
• W4223543204 cites W2888113435 @default.
• W4223543204 cites W2888723305 @default.
• W4223543204 cites W2891104345 @default.
• W4223543204 cites W2891817575 @default.
• W4223543204 cites W2891945121 @default.
• W4223543204 cites W2893387317 @default.
• W4223543204 cites W2896820459 @default.
• W4223543204 cites W2899429083 @default.
• W4223543204 cites W2899439484 @default.
• W4223543204 cites W2909040196 @default.
• W4223543204 cites W2910452042 @default.
• W4223543204 cites W2910820964 @default.
• W4223543204 cites W2950607694 @default.
• W4223543204 cites W2953222482 @default.
• W4223543204 cites W2962409343 @default.
• W4223543204 cites W2966712295 @default.
• W4223543204 cites W2980304360 @default.
• W4223543204 cites W3004280183 @default.
• W4223543204 cites W3009489858 @default.
• W4223543204 cites W3011146532 @default.
• W4223543204 cites W3025805667 @default.
• W4223543204 cites W3032969502 @default.
• W4223543204 cites W3096673836 @default.
• W4223543204 cites W3112217731 @default.
• W4223543204 cites W3136586043 @default.
• W4223543204 cites W3137782981 @default.
• W4223543204 cites W3154999102 @default.
• W4223543204 cites W3159735167 @default.
• W4223543204 cites W3165525129 @default.
• W4223543204 cites W3179610386 @default.
• W4223543204 cites W3189431822 @default.
• W4223543204 cites W3201850297 @default.
• W4223543204 cites W3209675340 @default.
• W4223543204 cites W4200220137 @default.

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