Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223558078> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4223558078 endingPage "127111" @default.
- W4223558078 startingPage "127111" @default.
- W4223558078 abstract "Medium-chain-length α, ω-diols (mcl-diols) are versatile compounds widely used as building blocks of coating materials and polymers. Mcl-diols are currently synthesized through energy intensive chemical process. Recently, esterified diols have been produced from n-alkanes in E. coli by co-expression of the alkane monooxygenase module (AlkBGTL) and the esterification module (Atf1), thereby establishing the technical feasibility of the process. However, esterified diols need to be hydrolyzed for further applications. In this study, we developed bio-catalysts for mcl-diol production from n-alkanes under mild conditions. The engineered P. putida KT2440 with overexpression of Est12 can efficiently hydrolyze esterified diols (C6-C10). Later, the engineered strain was co-cultured with an E. coli strain (AlkBGTL-Atf1) to produce mcl-diols. In a two-stage approach, 5 mM 1,6-hexanediol was produced, 61.5 times of one-stage test, from n-hexane by biocatalysts for the first time. In conclusion, the present work indicates that bio-catalysis offers a green biobased alternative for synthesis of mcl-diols." @default.
- W4223558078 created "2022-04-15" @default.
- W4223558078 creator A5003688889 @default.
- W4223558078 creator A5039324414 @default.
- W4223558078 creator A5053570180 @default.
- W4223558078 creator A5080008667 @default.
- W4223558078 creator A5081531718 @default.
- W4223558078 date "2022-05-01" @default.
- W4223558078 modified "2023-09-26" @default.
- W4223558078 title "Microbial production of medium-chain-length α, ω-diols via two-stage process under mild conditions" @default.
- W4223558078 cites W1535326178 @default.
- W4223558078 cites W1761632173 @default.
- W4223558078 cites W1972918463 @default.
- W4223558078 cites W1973633010 @default.
- W4223558078 cites W1977722568 @default.
- W4223558078 cites W2000485935 @default.
- W4223558078 cites W2023433267 @default.
- W4223558078 cites W2044814686 @default.
- W4223558078 cites W2044894294 @default.
- W4223558078 cites W2053618304 @default.
- W4223558078 cites W2056009551 @default.
- W4223558078 cites W2073499207 @default.
- W4223558078 cites W2076656429 @default.
- W4223558078 cites W2122254595 @default.
- W4223558078 cites W2144203019 @default.
- W4223558078 cites W2159010530 @default.
- W4223558078 cites W2263727947 @default.
- W4223558078 cites W2319219885 @default.
- W4223558078 cites W2528968705 @default.
- W4223558078 cites W2732691723 @default.
- W4223558078 cites W2762881569 @default.
- W4223558078 cites W2951067737 @default.
- W4223558078 cites W2961469667 @default.
- W4223558078 cites W3010972153 @default.
- W4223558078 cites W3011438738 @default.
- W4223558078 cites W3020576131 @default.
- W4223558078 cites W3045468480 @default.
- W4223558078 cites W3082605714 @default.
- W4223558078 cites W3089043784 @default.
- W4223558078 cites W3091957836 @default.
- W4223558078 cites W3093844660 @default.
- W4223558078 cites W3111323366 @default.
- W4223558078 cites W3126265139 @default.
- W4223558078 cites W3139329310 @default.
- W4223558078 cites W3210966112 @default.
- W4223558078 cites W3215068754 @default.
- W4223558078 cites W4200472089 @default.
- W4223558078 doi "https://doi.org/10.1016/j.biortech.2022.127111" @default.
- W4223558078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35381336" @default.
- W4223558078 hasPublicationYear "2022" @default.
- W4223558078 type Work @default.
- W4223558078 citedByCount "3" @default.
- W4223558078 countsByYear W42235580782023 @default.
- W4223558078 crossrefType "journal-article" @default.
- W4223558078 hasAuthorship W4223558078A5003688889 @default.
- W4223558078 hasAuthorship W4223558078A5039324414 @default.
- W4223558078 hasAuthorship W4223558078A5053570180 @default.
- W4223558078 hasAuthorship W4223558078A5080008667 @default.
- W4223558078 hasAuthorship W4223558078A5081531718 @default.
- W4223558078 hasBestOaLocation W42235580781 @default.
- W4223558078 hasConcept C161790260 @default.
- W4223558078 hasConcept C178790620 @default.
- W4223558078 hasConcept C181199279 @default.
- W4223558078 hasConcept C185592680 @default.
- W4223558078 hasConcept C191503008 @default.
- W4223558078 hasConcept C2779515768 @default.
- W4223558078 hasConcept C2780543182 @default.
- W4223558078 hasConcept C2781327020 @default.
- W4223558078 hasConcept C65024703 @default.
- W4223558078 hasConcept C94412978 @default.
- W4223558078 hasConceptScore W4223558078C161790260 @default.
- W4223558078 hasConceptScore W4223558078C178790620 @default.
- W4223558078 hasConceptScore W4223558078C181199279 @default.
- W4223558078 hasConceptScore W4223558078C185592680 @default.
- W4223558078 hasConceptScore W4223558078C191503008 @default.
- W4223558078 hasConceptScore W4223558078C2779515768 @default.
- W4223558078 hasConceptScore W4223558078C2780543182 @default.
- W4223558078 hasConceptScore W4223558078C2781327020 @default.
- W4223558078 hasConceptScore W4223558078C65024703 @default.
- W4223558078 hasConceptScore W4223558078C94412978 @default.
- W4223558078 hasLocation W42235580781 @default.
- W4223558078 hasLocation W42235580782 @default.
- W4223558078 hasOpenAccess W4223558078 @default.
- W4223558078 hasPrimaryLocation W42235580781 @default.
- W4223558078 hasRelatedWork W1966919070 @default.
- W4223558078 hasRelatedWork W2051972381 @default.
- W4223558078 hasRelatedWork W2058024767 @default.
- W4223558078 hasRelatedWork W2085747199 @default.
- W4223558078 hasRelatedWork W2110923675 @default.
- W4223558078 hasRelatedWork W2319030288 @default.
- W4223558078 hasRelatedWork W2748939376 @default.
- W4223558078 hasRelatedWork W2775796849 @default.
- W4223558078 hasRelatedWork W2950486392 @default.
- W4223558078 hasRelatedWork W2951316381 @default.
- W4223558078 hasVolume "352" @default.
- W4223558078 isParatext "false" @default.
- W4223558078 isRetracted "false" @default.
- W4223558078 workType "article" @default.