Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223603363> ?p ?o ?g. }
- W4223603363 endingPage "287" @default.
- W4223603363 startingPage "276" @default.
- W4223603363 abstract "The work assesses the performance of nanocarriers from amphiphilic block copolymers with functional azobenzene or coumarin moieties for delivery of paclitaxel. Placlitaxel was encapsulated by the nanoprecipitation method. Characterisations were performed by DLS, TEM, Zeta potential and HPLC. Cell viability was investigated in HeLa and Huh-5-2-cell lines. Coumarin-containing polymeric micelles (Dh = 26 ± 2 nm, PDI = 0.28, ζ = ‒22.9 ± 3.6 mV) with 11.2 ± 0.5%w/w drug loading showed enhanced cytotoxicity in HeLa cells (IC50 < 0.02 nM) compared to free paclitaxel (IC50 = 0.17 ± 0.02 nM). Azobenzene-containing polymeric vesicles (Dh = 390 ± 20 nm, PDI = 0.24, ζ = ‒33.2 ± 5.0 mV) with a 6.8 ± 0.4%w/w drug loading showed increased cytotoxicity under 530 nm light (IC50 = 0.0114 ± 0.00033 nM) in HeLa cells due to a stimulated delivery of paclitaxel. Effectivity of these block copolymers as paclitaxel nanovectors and light stimulated release has been demonstrated." @default.
- W4223603363 created "2022-04-15" @default.
- W4223603363 creator A5009361877 @default.
- W4223603363 creator A5023134670 @default.
- W4223603363 creator A5024501066 @default.
- W4223603363 creator A5025937104 @default.
- W4223603363 creator A5077706027 @default.
- W4223603363 creator A5088985185 @default.
- W4223603363 date "2022-04-03" @default.
- W4223603363 modified "2023-10-02" @default.
- W4223603363 title "Evaluation of PEG-<i>b</i>-polycarbonates self-assemblies containing azobenzene or coumarin moieties as nanocarriers using paclitaxel as a model hydrophobic drug" @default.
- W4223603363 cites W1946685615 @default.
- W4223603363 cites W1967104248 @default.
- W4223603363 cites W1983408077 @default.
- W4223603363 cites W2000957918 @default.
- W4223603363 cites W2003633578 @default.
- W4223603363 cites W2005419668 @default.
- W4223603363 cites W2013971224 @default.
- W4223603363 cites W2016722302 @default.
- W4223603363 cites W2023699389 @default.
- W4223603363 cites W2025291821 @default.
- W4223603363 cites W2036337806 @default.
- W4223603363 cites W2053613167 @default.
- W4223603363 cites W2069224110 @default.
- W4223603363 cites W2069394521 @default.
- W4223603363 cites W2070840273 @default.
- W4223603363 cites W2095976477 @default.
- W4223603363 cites W2115109524 @default.
- W4223603363 cites W2122245300 @default.
- W4223603363 cites W2167011671 @default.
- W4223603363 cites W2172186953 @default.
- W4223603363 cites W2181548792 @default.
- W4223603363 cites W2232308294 @default.
- W4223603363 cites W2324386494 @default.
- W4223603363 cites W2462921259 @default.
- W4223603363 cites W2556103485 @default.
- W4223603363 cites W2612502936 @default.
- W4223603363 cites W2701840719 @default.
- W4223603363 cites W2767282152 @default.
- W4223603363 cites W2783404219 @default.
- W4223603363 cites W2806032555 @default.
- W4223603363 cites W2889711951 @default.
- W4223603363 cites W2893450414 @default.
- W4223603363 cites W2900822292 @default.
- W4223603363 cites W2903907159 @default.
- W4223603363 cites W2996254071 @default.
- W4223603363 cites W3006549696 @default.
- W4223603363 cites W3008933977 @default.
- W4223603363 cites W3047728651 @default.
- W4223603363 cites W3088981963 @default.
- W4223603363 cites W3125500203 @default.
- W4223603363 cites W3137127863 @default.
- W4223603363 doi "https://doi.org/10.1080/02652048.2022.2061621" @default.
- W4223603363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35384769" @default.
- W4223603363 hasPublicationYear "2022" @default.
- W4223603363 type Work @default.
- W4223603363 citedByCount "1" @default.
- W4223603363 countsByYear W42236033632023 @default.
- W4223603363 crossrefType "journal-article" @default.
- W4223603363 hasAuthorship W4223603363A5009361877 @default.
- W4223603363 hasAuthorship W4223603363A5023134670 @default.
- W4223603363 hasAuthorship W4223603363A5024501066 @default.
- W4223603363 hasAuthorship W4223603363A5025937104 @default.
- W4223603363 hasAuthorship W4223603363A5077706027 @default.
- W4223603363 hasAuthorship W4223603363A5088985185 @default.
- W4223603363 hasConcept C109316439 @default.
- W4223603363 hasConcept C11268172 @default.
- W4223603363 hasConcept C12554922 @default.
- W4223603363 hasConcept C13965031 @default.
- W4223603363 hasConcept C141071460 @default.
- W4223603363 hasConcept C155672457 @default.
- W4223603363 hasConcept C15920480 @default.
- W4223603363 hasConcept C171250308 @default.
- W4223603363 hasConcept C178790620 @default.
- W4223603363 hasConcept C18150654 @default.
- W4223603363 hasConcept C184651966 @default.
- W4223603363 hasConcept C185592680 @default.
- W4223603363 hasConcept C192562407 @default.
- W4223603363 hasConcept C202751555 @default.
- W4223603363 hasConcept C21951064 @default.
- W4223603363 hasConcept C2776694085 @default.
- W4223603363 hasConcept C2777292972 @default.
- W4223603363 hasConcept C2777366897 @default.
- W4223603363 hasConcept C2778150588 @default.
- W4223603363 hasConcept C2779820397 @default.
- W4223603363 hasConcept C521977710 @default.
- W4223603363 hasConcept C55493867 @default.
- W4223603363 hasConcept C67407626 @default.
- W4223603363 hasConcept C71924100 @default.
- W4223603363 hasConcept C86181022 @default.
- W4223603363 hasConcept C86803240 @default.
- W4223603363 hasConceptScore W4223603363C109316439 @default.
- W4223603363 hasConceptScore W4223603363C11268172 @default.
- W4223603363 hasConceptScore W4223603363C12554922 @default.
- W4223603363 hasConceptScore W4223603363C13965031 @default.
- W4223603363 hasConceptScore W4223603363C141071460 @default.
- W4223603363 hasConceptScore W4223603363C155672457 @default.
- W4223603363 hasConceptScore W4223603363C15920480 @default.