Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223899377> ?p ?o ?g. }
- W4223899377 endingPage "339841" @default.
- W4223899377 startingPage "339841" @default.
- W4223899377 abstract "Herein, an antifouling electrochemical biosensor based on designed multifunctional peptides with two recognizing branches specific for one target was proposed to improve the target recognition efficiency and sensitivity. The designed multifunctional peptide contains two different recognizing branches (with sequences FYWHCLDE and FYCHTIDE) for immunoglobulin G (IgG), an antifouling sequence (EKEKEK) and an anchoring sequence (CPPPP), which can be immobilized onto the gold nanoparticles (AuNPs) and poly(3,4-ethylenedioxythiophene) (PEDOT) modified electrode surface. Owing to the synergistic effect of the two recognizing branches, the dual-recognizing peptide-based biosensor exhibited significantly enhanced sensitivity. Under the optimal experimental conditions, the biosensor for IgG exhibited a linear response range of 0.1 pg/mL to 0.1 μg/mL, with a limit of detection of 0.031 pg/mL (about 2 orders of magnitude lower than that of the normal biosensor). Moreover, the biosensor was also capable of assaying IgG in real biological samples such as human serum without suffering from significant biofouling. This strategy for biosensor construction not only ensures the ultra-sensitivity for target detection, but also effectively avoids biofouling on sensing interfaces in complex biological media." @default.
- W4223899377 created "2022-04-19" @default.
- W4223899377 creator A5006190424 @default.
- W4223899377 creator A5012718640 @default.
- W4223899377 creator A5035386529 @default.
- W4223899377 creator A5042896976 @default.
- W4223899377 creator A5053683203 @default.
- W4223899377 creator A5056448190 @default.
- W4223899377 creator A5090418115 @default.
- W4223899377 date "2022-05-01" @default.
- W4223899377 modified "2023-09-23" @default.
- W4223899377 title "Designed multifunctional peptides with two recognizing branches specific for one target to achieve highly sensitive and low fouling electrochemical protein assay in human serum" @default.
- W4223899377 cites W1994076870 @default.
- W4223899377 cites W1994350577 @default.
- W4223899377 cites W2032641808 @default.
- W4223899377 cites W2122330055 @default.
- W4223899377 cites W2147015275 @default.
- W4223899377 cites W2502992426 @default.
- W4223899377 cites W2601646782 @default.
- W4223899377 cites W2749877875 @default.
- W4223899377 cites W2900844982 @default.
- W4223899377 cites W2908190446 @default.
- W4223899377 cites W2911293488 @default.
- W4223899377 cites W2919954141 @default.
- W4223899377 cites W2946344716 @default.
- W4223899377 cites W2951008812 @default.
- W4223899377 cites W2967335838 @default.
- W4223899377 cites W2986077039 @default.
- W4223899377 cites W3005645631 @default.
- W4223899377 cites W3011656331 @default.
- W4223899377 cites W3022170256 @default.
- W4223899377 cites W3045417176 @default.
- W4223899377 cites W3048369991 @default.
- W4223899377 cites W3087754391 @default.
- W4223899377 cites W3089507474 @default.
- W4223899377 cites W3112193977 @default.
- W4223899377 cites W3126705116 @default.
- W4223899377 cites W3131667085 @default.
- W4223899377 cites W3158854644 @default.
- W4223899377 cites W3174802992 @default.
- W4223899377 cites W3193589416 @default.
- W4223899377 cites W3203073177 @default.
- W4223899377 cites W3216066996 @default.
- W4223899377 cites W3217320024 @default.
- W4223899377 cites W4361774076 @default.
- W4223899377 cites W3149406944 @default.
- W4223899377 doi "https://doi.org/10.1016/j.aca.2022.339841" @default.
- W4223899377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35525592" @default.
- W4223899377 hasPublicationYear "2022" @default.
- W4223899377 type Work @default.
- W4223899377 citedByCount "2" @default.
- W4223899377 countsByYear W42238993772023 @default.
- W4223899377 crossrefType "journal-article" @default.
- W4223899377 hasAuthorship W4223899377A5006190424 @default.
- W4223899377 hasAuthorship W4223899377A5012718640 @default.
- W4223899377 hasAuthorship W4223899377A5035386529 @default.
- W4223899377 hasAuthorship W4223899377A5042896976 @default.
- W4223899377 hasAuthorship W4223899377A5053683203 @default.
- W4223899377 hasAuthorship W4223899377A5056448190 @default.
- W4223899377 hasAuthorship W4223899377A5090418115 @default.
- W4223899377 hasConcept C10349863 @default.
- W4223899377 hasConcept C10390740 @default.
- W4223899377 hasConcept C104819515 @default.
- W4223899377 hasConcept C119128265 @default.
- W4223899377 hasConcept C155672457 @default.
- W4223899377 hasConcept C160756335 @default.
- W4223899377 hasConcept C171250308 @default.
- W4223899377 hasConcept C185592680 @default.
- W4223899377 hasConcept C192562407 @default.
- W4223899377 hasConcept C21951064 @default.
- W4223899377 hasConcept C2779281246 @default.
- W4223899377 hasConcept C41625074 @default.
- W4223899377 hasConcept C43617362 @default.
- W4223899377 hasConcept C55493867 @default.
- W4223899377 hasConcept C6047279 @default.
- W4223899377 hasConceptScore W4223899377C10349863 @default.
- W4223899377 hasConceptScore W4223899377C10390740 @default.
- W4223899377 hasConceptScore W4223899377C104819515 @default.
- W4223899377 hasConceptScore W4223899377C119128265 @default.
- W4223899377 hasConceptScore W4223899377C155672457 @default.
- W4223899377 hasConceptScore W4223899377C160756335 @default.
- W4223899377 hasConceptScore W4223899377C171250308 @default.
- W4223899377 hasConceptScore W4223899377C185592680 @default.
- W4223899377 hasConceptScore W4223899377C192562407 @default.
- W4223899377 hasConceptScore W4223899377C21951064 @default.
- W4223899377 hasConceptScore W4223899377C2779281246 @default.
- W4223899377 hasConceptScore W4223899377C41625074 @default.
- W4223899377 hasConceptScore W4223899377C43617362 @default.
- W4223899377 hasConceptScore W4223899377C55493867 @default.
- W4223899377 hasConceptScore W4223899377C6047279 @default.
- W4223899377 hasFunder F4320321001 @default.
- W4223899377 hasLocation W42238993771 @default.
- W4223899377 hasLocation W42238993772 @default.
- W4223899377 hasOpenAccess W4223899377 @default.
- W4223899377 hasPrimaryLocation W42238993771 @default.
- W4223899377 hasRelatedWork W133679337 @default.
- W4223899377 hasRelatedWork W1950305724 @default.
- W4223899377 hasRelatedWork W2007544241 @default.