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- W4223914894 abstract "Abstract Background To date, extensive experience in transcatheter closure of fenestrated atrial septal aneurysm (ASA) in the pediatric population is limited. Methods To report on procedural feasibility, efficacy, and long‐term outcome, we enrolled all children submitted to an attempt of transcatheter closure of fenestrated ASA at two, large volume, pediatric cardiology units (Naples and Massa, Italy) between April 2000 to May 2020. Results This retrospective study included 139 patients (median age 9 years [range 2–18] and weight 36 kg [range 10–102]); 19 (13.7%) children were ≤20 kg (range 10–20) and 14 (10.1%) were ≤5 years old. Single perforation was observed in 28 patients (20.1%), while 111 patients (79.9%) had multifenestrated ASA. The median size of the main defect was 15 mm (range 6–34) and 25 patients (18%) had a defect ≥20 mm. The procedural success rate was 99% (95% confidence interval [CI]: 94.9–99.8) using a single device in 75 (69%), two devices in 31 (28%), and three devices in 3 (3%) cases. Early minor adverse events (AEs) occurred in four patients (2.8%). Late minor AEs were recorded in one patient (0.7%) over a median follow‐up of 5 years ([range 0–18 years; total 890.2 person‐years, and with 30 patients (22%) followed ≥10 years). Neither mortality nor major AEs were recorded. Freedom from AEs was 99.1% at 10–15 years (95% CI: 93.5–99.8%), without any difference according to atrial septum anatomy or patient age and weight. Conclusion Transcatheter closure of fenestrated ASA is technically feasible and effective in children with excellent long‐term outcomes." @default.
- W4223914894 created "2022-04-19" @default.
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- W4223914894 date "2022-04-14" @default.
- W4223914894 modified "2023-09-26" @default.
- W4223914894 title "Transcatheter closure of fenestrated atrial septal aneurysm in children: Feasibility and long‐term results" @default.
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- W4223914894 doi "https://doi.org/10.1002/ccd.30191" @default.
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