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- W4223923340 abstract "Bilateral macronodular adrenal hyperplasia (BMAH) is typically a computed tomography (CT)-based diagnosis. Patients with multiple endocrine neoplasia type 1 (MEN-1) may present with normal-appearing adrenal glands, solitary adrenal adenomas, or BMAH. When adrenal nodularity is detected in a patient with MEN-1, it is important to determine if it is associated glucocorticoid secretory autonomy—either clinically evident Cushing syndrome or subclinical Cushing syndrome (also referred to as “mild autonomous cortisol excess”). When BMAH is associated with glucocorticoid secretory autonomy, adrenal venous sampling is not needed because, by definition, the disorder is bilateral. Dependent on the degree of symptomatology and comorbidities, management options include observation, unilateral adrenalectomy of the larger adrenal gland, or bilateral adrenalectomy. If the patient has subclinical Cushing syndrome (mild autonomous cortisol excess), then there is the opportunity to resect the larger adrenal gland to debulk the disease. Herein we share such a case." @default.
- W4223923340 created "2022-04-19" @default.
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- W4223923340 date "2023-01-01" @default.
- W4223923340 modified "2023-09-29" @default.
- W4223923340 title "Bilateral Macronodular Adrenal Hyperplasia in the Setting of Multiple Endocrine Neoplasia Type 1" @default.
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- W4223923340 doi "https://doi.org/10.1016/b978-0-323-79285-1.00084-4" @default.
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