Matches in SemOpenAlex for { <https://semopenalex.org/work/W4223937645> ?p ?o ?g. }
- W4223937645 endingPage "272" @default.
- W4223937645 startingPage "265" @default.
- W4223937645 abstract "A polycystic ovarian syndrome (PCOS) is the most common endocrine disorder affecting females. Furthermore, it is a heterogeneous disease with a variety of etiologies and outcomes. Patients frequently complain about infertility, irregular menstruation, acne, seborrheic dermatitis, hirsutism, and obesity. PCOS can be caused by hypothalamic-pituitary-ovarian axis dysfunction, heredity, or metabolic abnormalities. PCOS is characterized by chronic low-level inflammation, which includes an imbalance in pro-inflammatory factor secretion, endothelial cell dysfunction, and leukocytosis. PCOS is also distinguished by hormonal and immune dysregulation. During PCOS, immune cells and immune regulatory molecules play critical roles in maintaining metabolic homeostasis and regulating immune responses. Because of oligo/anovulation, patients with PCOS have low progesterone levels. Therefore, low progesterone levels in PCOS overstimulate the immune system, causing it to produce more estrogen, which leads to a variety of autoantibodies. This review aims to summarize the immune regulation involved in the pathogenesis of PCOS and pave the way for the development of better PCOS treatment options in the near future." @default.
- W4223937645 created "2022-04-19" @default.
- W4223937645 creator A5042169426 @default.
- W4223937645 creator A5050702153 @default.
- W4223937645 creator A5071798264 @default.
- W4223937645 creator A5077682260 @default.
- W4223937645 creator A5079286679 @default.
- W4223937645 creator A5084897152 @default.
- W4223937645 date "2022-06-01" @default.
- W4223937645 modified "2023-10-17" @default.
- W4223937645 title "Immune regulation in polycystic ovary syndrome" @default.
- W4223937645 cites W1530652841 @default.
- W4223937645 cites W1972238434 @default.
- W4223937645 cites W1981827774 @default.
- W4223937645 cites W1982664805 @default.
- W4223937645 cites W1992772931 @default.
- W4223937645 cites W1993060519 @default.
- W4223937645 cites W1999906527 @default.
- W4223937645 cites W2002638967 @default.
- W4223937645 cites W2006977640 @default.
- W4223937645 cites W2007856912 @default.
- W4223937645 cites W2008882618 @default.
- W4223937645 cites W2018924501 @default.
- W4223937645 cites W2021017358 @default.
- W4223937645 cites W2026513092 @default.
- W4223937645 cites W2029329880 @default.
- W4223937645 cites W2034142534 @default.
- W4223937645 cites W2044160710 @default.
- W4223937645 cites W2047285762 @default.
- W4223937645 cites W2050957540 @default.
- W4223937645 cites W2053442897 @default.
- W4223937645 cites W2054148469 @default.
- W4223937645 cites W2079189416 @default.
- W4223937645 cites W2090371418 @default.
- W4223937645 cites W2090597210 @default.
- W4223937645 cites W2090942716 @default.
- W4223937645 cites W2093715225 @default.
- W4223937645 cites W2100687604 @default.
- W4223937645 cites W2106941637 @default.
- W4223937645 cites W2120489942 @default.
- W4223937645 cites W2126003141 @default.
- W4223937645 cites W2132302427 @default.
- W4223937645 cites W2137883218 @default.
- W4223937645 cites W2142114143 @default.
- W4223937645 cites W2151322992 @default.
- W4223937645 cites W2154248317 @default.
- W4223937645 cites W2156628653 @default.
- W4223937645 cites W2159984837 @default.
- W4223937645 cites W2282353418 @default.
- W4223937645 cites W2409413400 @default.
- W4223937645 cites W2417730212 @default.
- W4223937645 cites W2536917087 @default.
- W4223937645 cites W2590654260 @default.
- W4223937645 cites W2605126433 @default.
- W4223937645 cites W2611391119 @default.
- W4223937645 cites W2621472976 @default.
- W4223937645 cites W2783349442 @default.
- W4223937645 cites W2793519018 @default.
- W4223937645 cites W2799913711 @default.
- W4223937645 cites W2805739535 @default.
- W4223937645 cites W2886311168 @default.
- W4223937645 cites W2886548594 @default.
- W4223937645 cites W2901717410 @default.
- W4223937645 cites W291617465 @default.
- W4223937645 cites W2916262950 @default.
- W4223937645 cites W2941801625 @default.
- W4223937645 cites W2942352281 @default.
- W4223937645 cites W2951128772 @default.
- W4223937645 cites W2953073283 @default.
- W4223937645 cites W2971810055 @default.
- W4223937645 cites W2973007867 @default.
- W4223937645 cites W2977041418 @default.
- W4223937645 cites W2986900631 @default.
- W4223937645 cites W3015478916 @default.
- W4223937645 cites W3021737588 @default.
- W4223937645 cites W3036491423 @default.
- W4223937645 cites W3036640353 @default.
- W4223937645 cites W3039136404 @default.
- W4223937645 cites W3041010056 @default.
- W4223937645 cites W3045632928 @default.
- W4223937645 cites W3046697336 @default.
- W4223937645 cites W3048990418 @default.
- W4223937645 cites W3081822878 @default.
- W4223937645 cites W3105312674 @default.
- W4223937645 cites W3121369406 @default.
- W4223937645 cites W3126865766 @default.
- W4223937645 cites W3145310045 @default.
- W4223937645 cites W3152501265 @default.
- W4223937645 cites W3164771981 @default.
- W4223937645 cites W3168289851 @default.
- W4223937645 cites W3178833546 @default.
- W4223937645 cites W3191809995 @default.
- W4223937645 cites W3198773296 @default.
- W4223937645 cites W3202275076 @default.
- W4223937645 cites W4256605237 @default.
- W4223937645 doi "https://doi.org/10.1016/j.cca.2022.04.234" @default.
- W4223937645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35447143" @default.
- W4223937645 hasPublicationYear "2022" @default.