FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224056817> ?p ?o ?g. }

• W4224056817 endingPage "69" @default.
• W4224056817 startingPage "62" @default.
• W4224056817 abstract "Traditional epitranscriptome profiling approach relies on specific antibodies or chemical treatments to capture modified RNA molecules and then applies high throughput sequencing to identify their transcriptomic locations. However, due to the lack of suitable or high-quality antibodies, only a small proportion of the 170 documented RNA modifications were profiled with those approaches. Direct sequencing of native RNA molecules using Oxford Nanopore Technologies (ONT) enabled straight inspection of RNA modifications and offered a promising alternative solution. N6-methyladenosine (m6A) is known to cause characteristic changes and increased base call errors of ONT signals compared with non-modified adenosines, based on which, the m6A sites can be identified directly from ONT signals. Meanwhile, a number of studies have shown that it is possible to predict m6A sites from RNA primary sequences. Using the m6A sites revealed by Illumina technology as benchmark, we showed that, the accuracy of ONT-based m6A site prediction can be further increased by integrating additional information from the primary sequences of RNA (AUROC of 0.918), compared with using ONT signals only (AUROC 0.878 using Base call error features, and 0.804 using Tombo features), providing a new perspective for more reliable mining of the relatively noisy ONT signals." @default.
• W4224056817 created "2022-04-19" @default.
• W4224056817 creator A5049817947 @default.
• W4224056817 creator A5062284353 @default.
• W4224056817 creator A5066912329 @default.
• W4224056817 creator A5090892714 @default.
• W4224056817 date "2022-07-01" @default.
• W4224056817 modified "2023-09-23" @default.
• W4224056817 title "Primary sequence-assisted prediction of m6A RNA methylation sites from Oxford nanopore direct RNA sequencing data" @default.
• W4224056817 cites W1186776093 @default.
• W4224056817 cites W1566303667 @default.
• W4224056817 cites W1639542273 @default.
• W4224056817 cites W1895681508 @default.
• W4224056817 cites W1933156045 @default.
• W4224056817 cites W1991807334 @default.
• W4224056817 cites W2025496731 @default.
• W4224056817 cites W2039731962 @default.
• W4224056817 cites W2045281368 @default.
• W4224056817 cites W2065847836 @default.
• W4224056817 cites W2078964320 @default.
• W4224056817 cites W2091724447 @default.
• W4224056817 cites W2102872651 @default.
• W4224056817 cites W2126165721 @default.
• W4224056817 cites W2140978723 @default.
• W4224056817 cites W2147329079 @default.
• W4224056817 cites W2175514210 @default.
• W4224056817 cites W2180404227 @default.
• W4224056817 cites W2271995006 @default.
• W4224056817 cites W2287984595 @default.
• W4224056817 cites W2546967042 @default.
• W4224056817 cites W2597375791 @default.
• W4224056817 cites W2632544498 @default.
• W4224056817 cites W2754499625 @default.
• W4224056817 cites W2765620447 @default.
• W4224056817 cites W2769630486 @default.
• W4224056817 cites W2791600746 @default.
• W4224056817 cites W2794797435 @default.
• W4224056817 cites W2803510059 @default.
• W4224056817 cites W2890140563 @default.
• W4224056817 cites W2890517686 @default.
• W4224056817 cites W2891114629 @default.
• W4224056817 cites W2900694973 @default.
• W4224056817 cites W2902945209 @default.
• W4224056817 cites W2906996182 @default.
• W4224056817 cites W2912369228 @default.
• W4224056817 cites W2921763102 @default.
• W4224056817 cites W2953460056 @default.
• W4224056817 cites W2954907383 @default.
• W4224056817 cites W2955930197 @default.
• W4224056817 cites W2962780260 @default.
• W4224056817 cites W2971454256 @default.
• W4224056817 cites W2973421587 @default.
• W4224056817 cites W2980511028 @default.
• W4224056817 cites W2995260704 @default.
• W4224056817 cites W2999689892 @default.
• W4224056817 cites W3010754381 @default.
• W4224056817 cites W3018119582 @default.
• W4224056817 cites W3023127603 @default.
• W4224056817 cites W3034921317 @default.
• W4224056817 cites W3043981686 @default.
• W4224056817 cites W3081143873 @default.
• W4224056817 cites W3090748508 @default.
• W4224056817 cites W3119738125 @default.
• W4224056817 cites W3145946957 @default.
• W4224056817 cites W3159776513 @default.
• W4224056817 cites W3163227633 @default.
• W4224056817 cites W3174760894 @default.
• W4224056817 cites W3174855653 @default.
• W4224056817 cites W3181626680 @default.
• W4224056817 cites W3184504420 @default.
• W4224056817 cites W4206583799 @default.
• W4224056817 cites W776567260 @default.
• W4224056817 doi "https://doi.org/10.1016/j.ymeth.2022.04.003" @default.
• W4224056817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35429629" @default.
• W4224056817 hasPublicationYear "2022" @default.
• W4224056817 type Work @default.
• W4224056817 citedByCount "3" @default.
• W4224056817 countsByYear W42240568172022 @default.
• W4224056817 countsByYear W42240568172023 @default.
• W4224056817 crossrefType "journal-article" @default.
• W4224056817 hasAuthorship W4224056817A5049817947 @default.
• W4224056817 hasAuthorship W4224056817A5062284353 @default.
• W4224056817 hasAuthorship W4224056817A5066912329 @default.
• W4224056817 hasAuthorship W4224056817A5090892714 @default.
• W4224056817 hasConcept C104317684 @default.
• W4224056817 hasConcept C126513998 @default.
• W4224056817 hasConcept C132917006 @default.
• W4224056817 hasConcept C141231307 @default.
• W4224056817 hasConcept C141795571 @default.
• W4224056817 hasConcept C171250308 @default.
• W4224056817 hasConcept C192562407 @default.
• W4224056817 hasConcept C51679486 @default.
• W4224056817 hasConcept C54355233 @default.
• W4224056817 hasConcept C67705224 @default.
• W4224056817 hasConcept C70721500 @default.
• W4224056817 hasConcept C86803240 @default.
• W4224056817 hasConceptScore W4224056817C104317684 @default.
• W4224056817 hasConceptScore W4224056817C126513998 @default.

• next