FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4224089611> ?p ?o ?g. }

• W4224089611 endingPage "421" @default.
• W4224089611 startingPage "421" @default.
• W4224089611 abstract "<ns4:p><ns4:bold>Background: </ns4:bold>Skin disease is the fourth most common disease among all diseases. The number of cases of skin diseases continues to increase, and people commonly use antibiotics to treat these diseases. Nevertheless, overuse of antibiotics can increase the resistance of these pathogens. Hence, the study of novel antibiotic compounds against multi-drug resistant (MDR) skin pathogens is urgently needed.</ns4:p><ns4:p> <ns4:bold>Methods:</ns4:bold> This study describes the antimicrobial diversity of bacteria associated with three species of marine nudibranchs (<ns4:italic>Jorunna funebris</ns4:italic>,<ns4:italic> Gymnodoris rubropapulosa,</ns4:italic> and <ns4:italic>Glossodoris atromarginata</ns4:italic>) sampled from Jepara coastal waters, the North Java Sea in August 2020. A total of 115 bacterial strains were selected for their prospective antipathogenic compounds against the pathogens <ns4:italic>Cutibacterium acnes</ns4:italic>, <ns4:italic>Staphylococcus aureus</ns4:italic>, <ns4:italic>Candida albicans,</ns4:italic> and <ns4:italic>Malassezia furfur</ns4:italic>.</ns4:p><ns4:p> <ns4:bold>Results:</ns4:bold> A total of 24 bacterial isolates (20.87%) exhibited antimicrobial activity against the pathogens that were selected and molecularly identified. Analyses of the gene of 16S rRNA discovered that these 24 isolates were associated with 11 genera of the phyla Firmicutes, Proteobacteria, and Actinobacteria, including <ns4:italic>Bacillus</ns4:italic> as the dominant genus, followed by <ns4:italic>Streptomyces, Gordonia, Salinicola</ns4:italic>, <ns4:italic>Thalassospira</ns4:italic>, <ns4:italic>Halomonas, Dietzia, Brevibacterium, Paracoccus</ns4:italic>, <ns4:italic>Pseudovibrio, Pseudoalteromonas, </ns4:italic>and <ns4:italic>Pseudomonas</ns4:italic>. None of the 24 antimicrobial bacterial strains possessed type-1 polyketide synthases (PKS-I). One strain possessed type II polyketide synthases (PKS-II), and five strains possessed non-ribosomal peptide synthetase (NRPS) genes. The amounts of bacterial genus and strains in the three nudibranchs differed significantly, as did the proportions of antimicrobial strains in each nudibranch species. The antibacterial strains isolated from <ns4:italic>G.</ns4:italic> <ns4:italic>atromarginata</ns4:italic> were the highest number (62.5%), followed by<ns4:italic> J. funebris</ns4:italic> (20.8%) and <ns4:italic>G.</ns4:italic> <ns4:italic>rubropapulosa</ns4:italic> (16.7%).</ns4:p><ns4:p> <ns4:bold>Conclusions:</ns4:bold> These results demonstrate that nudibranch species harbor prominent and varied communities of bacteria and reveal that many nudibranch-associated bacteria have the potential for the advancement of broad-spectrum antibiotics.</ns4:p>" @default.
• W4224089611 created "2022-04-19" @default.
• W4224089611 creator A5030330832 @default.
• W4224089611 creator A5038075124 @default.
• W4224089611 creator A5049637979 @default.
• W4224089611 creator A5051151817 @default.
• W4224089611 creator A5056673292 @default.
• W4224089611 creator A5086954108 @default.
• W4224089611 date "2022-04-13" @default.
• W4224089611 modified "2023-10-14" @default.
• W4224089611 title "Diversity and antimicrobial activity of marine nudibranch associated bacteria against tropical human skin pathogens" @default.
• W4224089611 cites W1009262001 @default.
• W4224089611 cites W2000511588 @default.
• W4224089611 cites W2022047620 @default.
• W4224089611 cites W2022884417 @default.
• W4224089611 cites W2039813270 @default.
• W4224089611 cites W2044688672 @default.
• W4224089611 cites W2088956091 @default.
• W4224089611 cites W2097382368 @default.
• W4224089611 cites W2141668953 @default.
• W4224089611 cites W2152555393 @default.
• W4224089611 cites W2172321569 @default.
• W4224089611 cites W2185564569 @default.
• W4224089611 cites W2202622350 @default.
• W4224089611 cites W2594455611 @default.
• W4224089611 cites W2624727754 @default.
• W4224089611 cites W2626112736 @default.
• W4224089611 cites W2726683946 @default.
• W4224089611 cites W2766928849 @default.
• W4224089611 cites W2767031614 @default.
• W4224089611 cites W2902636114 @default.
• W4224089611 cites W2903518495 @default.
• W4224089611 cites W2954903399 @default.
• W4224089611 cites W2957761752 @default.
• W4224089611 cites W2970193442 @default.
• W4224089611 cites W2985037021 @default.
• W4224089611 cites W2998168579 @default.
• W4224089611 cites W3000302299 @default.
• W4224089611 cites W3007886540 @default.
• W4224089611 cites W3012632193 @default.
• W4224089611 cites W3035354883 @default.
• W4224089611 cites W3038985367 @default.
• W4224089611 cites W3101114207 @default.
• W4224089611 cites W3116803898 @default.
• W4224089611 cites W3120265928 @default.
• W4224089611 cites W3126909395 @default.
• W4224089611 cites W3200766687 @default.
• W4224089611 doi "https://doi.org/10.12688/f1000research.108857.1" @default.
• W4224089611 hasPublicationYear "2022" @default.
• W4224089611 type Work @default.
• W4224089611 citedByCount "2" @default.
• W4224089611 countsByYear W42240896112022 @default.
• W4224089611 countsByYear W42240896112023 @default.
• W4224089611 crossrefType "journal-article" @default.
• W4224089611 hasAuthorship W4224089611A5030330832 @default.
• W4224089611 hasAuthorship W4224089611A5038075124 @default.
• W4224089611 hasAuthorship W4224089611A5049637979 @default.
• W4224089611 hasAuthorship W4224089611A5051151817 @default.
• W4224089611 hasAuthorship W4224089611A5056673292 @default.
• W4224089611 hasAuthorship W4224089611A5086954108 @default.
• W4224089611 hasBestOaLocation W42240896111 @default.
• W4224089611 hasConcept C202751555 @default.
• W4224089611 hasConcept C2776635100 @default.
• W4224089611 hasConcept C54355233 @default.
• W4224089611 hasConcept C86803240 @default.
• W4224089611 hasConceptScore W4224089611C202751555 @default.
• W4224089611 hasConceptScore W4224089611C2776635100 @default.
• W4224089611 hasConceptScore W4224089611C54355233 @default.
• W4224089611 hasConceptScore W4224089611C86803240 @default.
• W4224089611 hasLocation W42240896111 @default.
• W4224089611 hasOpenAccess W4224089611 @default.
• W4224089611 hasPrimaryLocation W42240896111 @default.
• W4224089611 hasRelatedWork W154464832 @default.
• W4224089611 hasRelatedWork W1706786352 @default.
• W4224089611 hasRelatedWork W2010962910 @default.
• W4224089611 hasRelatedWork W2017763696 @default.
• W4224089611 hasRelatedWork W2026654669 @default.
• W4224089611 hasRelatedWork W2066595253 @default.
• W4224089611 hasRelatedWork W2088329399 @default.
• W4224089611 hasRelatedWork W3121605926 @default.
• W4224089611 hasRelatedWork W1582258830 @default.
• W4224089611 hasRelatedWork W2338506910 @default.
• W4224089611 hasVolume "11" @default.
• W4224089611 isParatext "false" @default.
• W4224089611 isRetracted "false" @default.
• W4224089611 workType "article" @default.